Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
| Location | 2109975..2110495 | Replicon | chromosome |
| Accession | NZ_CP031454 | ||
| Organism | Burkholderia gladioli strain Lv-StA | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | - |
| Locus tag | DX980_RS29935 | Protein ID | WP_084152421.1 |
| Coordinates | 2110271..2110495 (-) | Length | 75 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | DX980_RS29930 | Protein ID | WP_036032828.1 |
| Coordinates | 2109975..2110274 (-) | Length | 100 a.a. |
Genomic Context
Location: 2108680..2109870 (1191 bp)
Type: Others
Protein ID: WP_160294540.1
Type: Others
Protein ID: WP_160294540.1
Location: 2110783..2112336 (1554 bp)
Type: Others
Protein ID: WP_160294541.1
Type: Others
Protein ID: WP_160294541.1
Location: 2112371..2112826 (456 bp)
Type: Others
Protein ID: WP_160294542.1
Type: Others
Protein ID: WP_160294542.1
Location: 2114754..2115245 (492 bp)
Type: Others
Protein ID: WP_025097476.1
Type: Others
Protein ID: WP_025097476.1
Location: 2105319..2105774 (456 bp)
Type: Others
Protein ID: WP_013689018.1
Type: Others
Protein ID: WP_013689018.1
Location: 2105895..2106179 (285 bp)
Type: Others
Protein ID: WP_172535078.1
Type: Others
Protein ID: WP_172535078.1
Location: 2106351..2106596 (246 bp)
Type: Others
Protein ID: WP_046576040.1
Type: Others
Protein ID: WP_046576040.1
Location: 2106626..2108032 (1407 bp)
Type: Others
Protein ID: WP_105827196.1
Type: Others
Protein ID: WP_105827196.1
Location: 2109975..2110274 (300 bp)
Type: Antitoxin
Protein ID: WP_036032828.1
Type: Antitoxin
Protein ID: WP_036032828.1
Location: 2110271..2110495 (225 bp)
Type: Toxin
Protein ID: WP_084152421.1
Type: Toxin
Protein ID: WP_084152421.1
Location: 2112883..2114307 (1425 bp)
Type: Others
Protein ID: WP_160294543.1
Type: Others
Protein ID: WP_160294543.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DX980_RS29905 (DX980_29560) | 2105319..2105774 | - | 456 | WP_013689018.1 | CesT family type III secretion system chaperone | - |
| DX980_RS29910 (DX980_29565) | 2105895..2106179 | - | 285 | WP_172535078.1 | hypothetical protein | - |
| DX980_RS29915 (DX980_29570) | 2106351..2106596 | - | 246 | WP_046576040.1 | hypothetical protein | - |
| DX980_RS29920 (DX980_29575) | 2106626..2108032 | - | 1407 | WP_105827196.1 | type III secretion protein | - |
| DX980_RS29925 (DX980_29580) | 2108680..2109870 | + | 1191 | WP_160294540.1 | MFS transporter | - |
| DX980_RS29930 (DX980_29585) | 2109975..2110274 | - | 300 | WP_036032828.1 | putative addiction module antidote protein | Antitoxin |
| DX980_RS29935 (DX980_29590) | 2110271..2110495 | - | 225 | WP_084152421.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| DX980_RS29940 (DX980_29595) | 2110783..2112336 | + | 1554 | WP_160294541.1 | hypothetical protein | - |
| DX980_RS29945 (DX980_29600) | 2112371..2112826 | + | 456 | WP_160294542.1 | NUDIX domain-containing protein | - |
| DX980_RS29950 (DX980_29605) | 2112883..2114307 | - | 1425 | WP_160294543.1 | class I SAM-dependent methyltransferase | - |
| DX980_RS29955 (DX980_29610) | 2114754..2115245 | + | 492 | WP_025097476.1 | MarR family transcriptional regulator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 75 a.a. Molecular weight: 8134.38 Da Isoelectric Point: 10.1935
>T109214 WP_084152421.1 NZ_CP031454:c2110495-2110271 [Burkholderia gladioli]
MAFFGYRIPDNRHACARGNGVSELRIDHGPGYRVYYMKRGRVVVILLCGGNKDSQGHDIAVAKAIAAQWKGSTI
MAFFGYRIPDNRHACARGNGVSELRIDHGPGYRVYYMKRGRVVVILLCGGNKDSQGHDIAVAKAIAAQWKGSTI
Download Length: 225 bp
>T109214 NZ_CP031454:c2110495-2110271 [Burkholderia gladioli]
ATGGCTTTTTTCGGATATCGCATCCCGGACAATCGACACGCCTGCGCCCGTGGCAACGGTGTCTCGGAACTGCGAATCGA
CCATGGCCCTGGATATCGGGTCTACTACATGAAGCGAGGCCGCGTCGTGGTCATATTGCTATGCGGCGGCAATAAGGATA
GTCAAGGTCATGACATTGCCGTCGCCAAGGCAATCGCTGCGCAATGGAAGGGGTCCACGATATGA
ATGGCTTTTTTCGGATATCGCATCCCGGACAATCGACACGCCTGCGCCCGTGGCAACGGTGTCTCGGAACTGCGAATCGA
CCATGGCCCTGGATATCGGGTCTACTACATGAAGCGAGGCCGCGTCGTGGTCATATTGCTATGCGGCGGCAATAAGGATA
GTCAAGGTCATGACATTGCCGTCGCCAAGGCAATCGCTGCGCAATGGAAGGGGTCCACGATATGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10596.95 Da Isoelectric Point: 4.7420
>AT109214 WP_036032828.1 NZ_CP031454:c2110274-2109975 [Burkholderia gladioli]
MKAVKFSRYDTVDYLQTEEEIAAYLDAAVEDGDPALIAAALGDIARARNISQLARDTGMSREGIYRALSGDGNPSFATVM
KIANALGLRISFRPATSSP
MKAVKFSRYDTVDYLQTEEEIAAYLDAAVEDGDPALIAAALGDIARARNISQLARDTGMSREGIYRALSGDGNPSFATVM
KIANALGLRISFRPATSSP
Download Length: 300 bp
>AT109214 NZ_CP031454:c2110274-2109975 [Burkholderia gladioli]
ATGAAAGCCGTGAAGTTCAGTCGATACGATACCGTCGACTATCTGCAGACCGAGGAGGAGATTGCCGCCTACCTCGACGC
TGCGGTCGAAGACGGCGATCCGGCCTTGATCGCCGCAGCCCTTGGTGACATCGCGCGTGCGCGAAATATCAGCCAACTCG
CGCGCGATACCGGCATGAGTCGCGAAGGCATTTATCGGGCCCTGTCGGGTGACGGCAATCCGAGTTTTGCTACCGTGATG
AAAATTGCGAATGCGCTTGGGCTACGGATATCCTTTCGACCCGCGACATCGAGCCCATGA
ATGAAAGCCGTGAAGTTCAGTCGATACGATACCGTCGACTATCTGCAGACCGAGGAGGAGATTGCCGCCTACCTCGACGC
TGCGGTCGAAGACGGCGATCCGGCCTTGATCGCCGCAGCCCTTGGTGACATCGCGCGTGCGCGAAATATCAGCCAACTCG
CGCGCGATACCGGCATGAGTCGCGAAGGCATTTATCGGGCCCTGTCGGGTGACGGCAATCCGAGTTTTGCTACCGTGATG
AAAATTGCGAATGCGCTTGGGCTACGGATATCCTTTCGACCCGCGACATCGAGCCCATGA