Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 36086..37803 Replicon plasmid unnamed2
Accession NZ_CP031453
Organism Burkholderia gladioli strain Lv-StA

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag DX980_RS20630 Protein ID WP_160293878.1
Coordinates 36086..36730 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag DX980_RS20635 Protein ID WP_160293879.1
Coordinates 36730..37803 (+) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DX980_RS20615 (DX980_20525) 32285..32554 + 270 WP_160293875.1 hypothetical protein -
DX980_RS20620 (DX980_20530) 32864..33529 - 666 WP_160293876.1 hypothetical protein -
DX980_RS20625 (DX980_20535) 33827..35683 - 1857 WP_160293877.1 site-specific integrase -
DX980_RS20630 (DX980_20540) 36086..36730 + 645 WP_160293878.1 DUF4433 domain-containing protein Toxin
DX980_RS20635 (DX980_20545) 36730..37803 + 1074 WP_160293879.1 macro domain-containing protein Antitoxin
DX980_RS20640 (DX980_20550) 38508..39437 + 930 WP_160293880.1 hypothetical protein -
DX980_RS20645 (DX980_20555) 39434..41290 + 1857 WP_160293881.1 hypothetical protein -
DX980_RS20650 41294..42235 + 942 WP_160293882.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..101882 101882


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(15-214)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24793.51 Da        Isoelectric Point: 7.4398

>T109212 WP_160293878.1 NZ_CP031453:36086-36730 [Burkholderia gladioli]
MANYQRLNAENAYIWRIVHRQNLPWILDHGLVCANSGLLDPNFVPIGNADLISRRRLRVVPVAPGGTLSDYVPFYFTPFS
PMMYNIHTGRTVRQQRNEDICMLVSTLPVLQQMGIPFVFTDRHAYTQLARFFRDLGELGHIDWPLLQARNFKRNPDDPEQ
IERYQAEALVYDHLPVNGLTAIVCYTEQVKVELEQLVAARRLSVTVQALPHWYF

Download         Length: 645 bp

>T109212 NZ_CP031453:36086-36730 [Burkholderia gladioli]
ATGGCGAACTATCAACGGCTCAACGCCGAGAACGCATACATTTGGCGCATCGTTCATCGCCAGAATCTTCCGTGGATCCT
GGACCACGGGCTGGTGTGCGCGAACAGCGGACTCCTCGACCCTAATTTCGTGCCGATCGGCAATGCGGATCTGATCAGCC
GGCGGAGGCTCCGGGTCGTCCCCGTCGCCCCTGGTGGAACATTGAGTGACTACGTGCCATTTTATTTCACGCCGTTTTCG
CCAATGATGTACAACATTCATACTGGACGAACCGTGCGCCAGCAGCGCAACGAGGACATCTGCATGCTCGTCAGCACGTT
GCCGGTCCTTCAGCAAATGGGTATACCGTTTGTCTTTACCGATCGACATGCATACACGCAGTTGGCGCGGTTCTTTCGCG
ATCTGGGGGAGTTGGGCCATATCGACTGGCCATTACTTCAGGCGCGGAACTTTAAGCGCAACCCGGACGATCCCGAGCAA
ATCGAGCGCTATCAAGCCGAGGCACTGGTCTATGATCATCTGCCGGTGAACGGACTCACTGCGATTGTGTGCTATACCGA
ACAGGTGAAAGTTGAACTGGAGCAGTTGGTGGCCGCGCGTCGTCTGAGTGTGACGGTGCAAGCGCTCCCCCACTGGTACT
TCTGA

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40312.35 Da        Isoelectric Point: 6.5077

>AT109212 WP_160293879.1 NZ_CP031453:36730-37803 [Burkholderia gladioli]
MITYTQGNLLDAPAEALVNTVNTVGVMGKGIALMFKEKFPENFRQYALACKEGRVHTGTVFVTERMELIGPKWIVNFPTK
RHWRAPSRLEWIVEGLADLRHFIEKEHIRSIAIPPLGAGNGGLDWPTVKAEIDAALGDMADTEILVYEPTGRYQNVSKRE
GVEKLTPARALIAELVRRYWILGMECTLLEIQKLAWFLERTIERTDAPNPLKLKFVAHTYGPYANRLDHLLNNLDGSYLH
CDKRIADAGPLDVIWFDDRRGDMLAAYLKSGEMRPYLPALEETASLIDGFESPFGLELLASLDWLLARDGRDPNLDSIRA
GFSAWPGGESAGRRKYRLFDERAIQIGLRRLTEHVPA

Download         Length: 1074 bp

>AT109212 NZ_CP031453:36730-37803 [Burkholderia gladioli]
ATGATTACATATACCCAAGGTAACCTGCTCGACGCTCCTGCCGAGGCGCTCGTCAACACGGTCAACACGGTTGGCGTGAT
GGGCAAAGGCATCGCGCTGATGTTTAAAGAAAAGTTTCCTGAGAACTTCCGCCAGTACGCGCTTGCTTGCAAAGAAGGGC
GCGTGCATACCGGCACGGTGTTCGTGACGGAACGCATGGAACTGATTGGGCCAAAGTGGATCGTCAACTTCCCGACTAAA
CGACATTGGCGTGCGCCTTCGCGGCTTGAATGGATTGTCGAGGGACTAGCCGATCTACGCCACTTCATCGAAAAAGAGCA
CATCCGATCGATCGCTATACCGCCGCTCGGCGCGGGCAATGGGGGTTTGGACTGGCCTACCGTGAAGGCCGAAATCGACG
CGGCGCTCGGCGATATGGCGGACACGGAGATTTTGGTCTACGAACCAACTGGCAGGTATCAGAATGTCTCAAAACGTGAG
GGTGTAGAGAAGCTGACTCCCGCCCGGGCGTTGATCGCCGAGCTTGTGCGACGATACTGGATCCTTGGCATGGAATGCAC
GTTGCTTGAGATTCAGAAGCTCGCGTGGTTCCTCGAGCGTACGATCGAGCGGACTGATGCGCCAAACCCGCTCAAGCTCA
AGTTTGTCGCACATACCTATGGGCCGTATGCGAATCGCCTAGATCATCTGTTGAACAACCTTGATGGCAGTTATTTGCAC
TGCGACAAGCGCATCGCCGACGCCGGCCCGCTCGACGTCATTTGGTTCGACGACCGTCGAGGCGACATGCTTGCAGCGTA
CCTCAAGAGCGGCGAGATGAGGCCGTATTTGCCCGCTCTTGAGGAGACCGCCTCTTTAATCGACGGGTTTGAATCACCGT
TCGGGCTTGAGCTTCTCGCGTCGTTAGATTGGTTGTTGGCCCGCGACGGGCGCGATCCCAATCTCGATAGCATTCGTGCG
GGCTTCTCGGCGTGGCCGGGCGGCGAGTCGGCGGGGCGGCGAAAATATCGACTGTTCGACGAGAGGGCAATTCAGATTGG
TTTGAGACGCCTGACCGAGCACGTCCCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References