Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 61453..62102 Replicon plasmid unnamed1
Accession NZ_CP031451
Organism Burkholderia gladioli strain Lv-StA

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DX980_RS00305 Protein ID WP_160292568.1
Coordinates 61692..62102 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DX980_RS00300 Protein ID WP_160292567.1
Coordinates 61453..61695 (+) Length 81 a.a.

Genomic Context

DX980_RS00275DX980_RS00280DX980_RS00290DX980_RS00295DX980_RS00300DX980_RS00305DX980_RS00310DX980_RS00315DX980_RS00320DX980_RS00325DX980_RS00330DX980_RS00335DX980_RS00340DX980_RS00345DX980_RS00350DX980_RS00270DX980_RS00285
Location: 59105..59440 (336 bp)
Type: Others
Protein ID: WP_236669213.1
Location: 59567..59789 (223 bp)
Type: Others
Protein ID: Protein_55
Location: 60840..61031 (192 bp)
Type: Others
Protein ID: Protein_57
Location: 61112..61213 (102 bp)
Type: Others
Protein ID: Protein_58
Location: 61453..61695 (243 bp)
Type: Antitoxin
Protein ID: WP_160292567.1
Location: 61692..62102 (411 bp)
Type: Toxin
Protein ID: WP_160292568.1
Location: 62520..62705 (186 bp)
Type: Others
Protein ID: WP_160292569.1
Location: 62846..63091 (246 bp)
Type: Others
Protein ID: WP_160292666.1
Location: 63081..63380 (300 bp)
Type: Others
Protein ID: WP_160292570.1
Location: 63400..63651 (252 bp)
Type: Others
Protein ID: WP_160292571.1
Location: 64058..64315 (258 bp)
Type: Others
Protein ID: WP_160292572.1
Location: 64974..65429 (456 bp)
Type: Others
Protein ID: WP_160292573.1
Location: 65433..65714 (282 bp)
Type: Others
Protein ID: WP_160292574.1
Location: 65901..66314 (414 bp)
Type: Others
Protein ID: WP_160292575.1
Location: 66542..66811 (270 bp)
Type: Others
Protein ID: WP_160292576.1
Location: 56546..56941 (396 bp)
Type: Others
Protein ID: WP_236669212.1
Location: 59764..60714 (951 bp)
Type: Others
Protein ID: WP_160292565.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DX980_RS00270 (DX980_00265)56546..56941-396WP_236669212.1hypothetical protein-
DX980_RS0027559105..59440+336WP_236669213.1DUF4400 domain-containing protein-
DX980_RS00280 (DX980_00280)59567..59789+223Protein_55IS5/IS1182 family transposase-
DX980_RS00285 (DX980_00285)59764..60714-951WP_160292565.1site-specific integrase-
DX980_RS00290 (DX980_00290)60840..61031+192Protein_57DUF2384 domain-containing protein-
DX980_RS00295 (DX980_00295)61112..61213+102Protein_58GNAT family N-acetyltransferase-
DX980_RS00300 (DX980_00300)61453..61695+243WP_160292567.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
DX980_RS00305 (DX980_00305)61692..62102+411WP_160292568.1type II toxin-antitoxin system VapC family toxinToxin
DX980_RS00310 (DX980_00310)62520..62705+186WP_160292569.1hypothetical protein-
DX980_RS00315 (DX980_00315)62846..63091+246WP_160292666.1type II toxin-antitoxin system ParD family antitoxin-
DX980_RS00320 (DX980_00320)63081..63380+300WP_160292570.1type II toxin-antitoxin system RelE/ParE family toxin-
DX980_RS00325 (DX980_00325)63400..63651+252WP_160292571.1hypothetical protein-
DX980_RS00330 (DX980_00330)64058..64315+258WP_160292572.1hypothetical protein-
DX980_RS00335 (DX980_00335)64974..65429+456WP_160292573.1hypothetical protein-
DX980_RS00340 (DX980_00340)65433..65714+282WP_160292574.1type II toxin-antitoxin system RelE/ParE family toxin-
DX980_RS00345 (DX980_00345)65901..66314+414WP_160292575.1DUF2384 domain-containing protein-
DX980_RS00350 (DX980_00350)66542..66811+270WP_160292576.1DUF1778 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..191503191503


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(12-48)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14799.27 Da        Isoelectric Point: 7.1076

>T109210 WP_160292568.1 NZ_CP031451:61692-62102 [Burkholderia gladioli]
MTMYLLDTSILSNVMRDPRGACATRIGLTPPEHLCTSIVVAAELRFGVLKRGSSMLAQRVEQLLASLPVLPLQADADRCY
GRLRAELEKQGQLIGANDMLIAAHALAVEAVLVTDNTAEFARVAGLRVENWLRPTT

Download         Length: 411 bp

>T109210 NZ_CP031451:61692-62102 [Burkholderia gladioli]
ATGACGATGTACCTGCTGGACACCAGCATCTTGTCCAATGTGATGCGAGACCCGCGCGGCGCCTGCGCCACCCGAATCGG
ACTGACGCCGCCTGAGCACCTTTGCACCTCGATCGTCGTGGCGGCAGAGCTGCGCTTTGGCGTCTTGAAACGCGGTTCGT
CGATGCTCGCGCAGCGCGTCGAGCAACTTCTCGCGAGCTTGCCCGTGCTGCCGTTGCAGGCCGACGCCGACCGGTGCTAC
GGCCGATTGCGGGCCGAGCTCGAGAAGCAAGGCCAGTTGATCGGCGCCAACGACATGCTGATCGCCGCGCACGCGCTGGC
GGTCGAGGCCGTTCTGGTGACGGACAACACGGCCGAATTTGCCCGAGTTGCTGGGCTGCGGGTCGAAAACTGGTTGCGGC
CGACGACGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9261.53 Da        Isoelectric Point: 4.6234

>AT109210 WP_160292567.1 NZ_CP031451:61453-61695 [Burkholderia gladioli]
MPTHDIRHARLFRNGRSQAVRIPREFELAVSEVTIYREGQRLIIEPVPAAPLRELFAQWPPLDETFPDIENLSAEPVDIE

Download         Length: 243 bp

>AT109210 NZ_CP031451:61453-61695 [Burkholderia gladioli]
ATGCCCACTCACGATATTCGCCATGCCCGGTTGTTTCGCAACGGACGCAGCCAGGCCGTGCGGATTCCGCGCGAGTTCGA
ACTCGCTGTCTCCGAGGTCACCATCTACCGGGAAGGCCAGCGCCTGATCATCGAGCCCGTCCCGGCCGCGCCCTTGCGTG
AGCTGTTTGCCCAATGGCCCCCCCTGGATGAAACGTTTCCCGACATCGAGAACCTGTCGGCCGAACCGGTCGACATCGAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References