109187

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 413851..414371 Replicon chromosome
Accession NZ_CP031422
Organism Microbacterium oxydans strain HG3

Toxin (Protein)


Gene name relE Uniprot ID A0A0M3DA52
Locus tag CVS54_RS02035 Protein ID WP_046746899.1
Coordinates 414108..414371 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0M3DCF4
Locus tag CVS54_RS02030 Protein ID WP_046746900.1
Coordinates 413851..414111 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS54_RS02005 409874..410545 - 672 WP_046746904.1 response regulator transcription factor -
CVS54_RS02010 410633..411295 + 663 WP_046746903.1 M15 family metallopeptidase -
CVS54_RS02015 411292..412416 + 1125 WP_127011645.1 alanine racemase -
CVS54_RS02020 412413..413360 + 948 WP_127011646.1 D-alanine--D-alanine ligase -
CVS54_RS02025 413414..413803 + 390 WP_046746974.1 VOC family protein -
CVS54_RS02030 413851..414111 + 261 WP_046746900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CVS54_RS02035 414108..414371 + 264 WP_046746899.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CVS54_RS02040 414464..415480 - 1017 WP_046746898.1 ABC transporter substrate-binding protein -
CVS54_RS02045 415491..416273 - 783 WP_127011647.1 ABC transporter ATP-binding protein -
CVS54_RS02050 416270..417415 - 1146 WP_197077665.1 iron ABC transporter permease -
CVS54_RS02055 417412..419202 - 1791 WP_127011648.1 prolyl oligopeptidase family serine peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-66)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10112.62 Da        Isoelectric Point: 9.8116

>T109187 WP_046746899.1 NZ_CP031422:414108-414371 [Microbacterium oxydans]
VTSYRVEFTTAAAKEIRKLDAQIRRRILVGIAELESDPRPPGVRKLSGYDNAWRVRIGDYRVLYEVIDDQVLVTVVRVAH
RRDVYEI

Download         Length: 264 bp

>T109187 NZ_CP031422:414108-414371 [Microbacterium oxydans]
GTGACGAGCTATCGGGTCGAATTCACCACAGCGGCCGCGAAAGAGATACGCAAACTCGACGCGCAGATCCGTCGACGGAT
TCTCGTCGGCATCGCTGAGTTGGAAAGCGATCCCCGCCCTCCCGGCGTCCGGAAGCTCTCCGGCTACGACAATGCCTGGC
GGGTGCGCATCGGCGACTACCGCGTTCTCTACGAGGTGATCGACGACCAGGTGCTCGTGACCGTGGTGCGTGTCGCCCAC
CGTCGAGACGTCTACGAGATCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9096.20 Da        Isoelectric Point: 4.3646

>AT109187 WP_046746900.1 NZ_CP031422:413851-414111 [Microbacterium oxydans]
MNTISRNVPSKDLRDSLADVLGGVAYGSERVGVTRHGKLTAVVISVADLELLEELEAARDAAEFATAKAADDGRRVSLDE
LVTEVA

Download         Length: 261 bp

>AT109187 NZ_CP031422:413851-414111 [Microbacterium oxydans]
ATGAACACGATCAGCCGCAACGTCCCGTCGAAGGATCTTCGCGACAGCTTGGCCGACGTTCTCGGAGGTGTCGCCTACGG
TTCCGAGCGCGTGGGCGTCACCCGCCACGGGAAGCTCACGGCCGTCGTGATCAGCGTGGCTGATCTGGAACTGCTCGAAG
AGCTCGAGGCCGCGCGCGATGCGGCCGAGTTCGCGACAGCCAAAGCTGCCGACGATGGCCGGCGGGTGTCGCTCGATGAG
CTCGTCACGGAAGTTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M3DA52

Antitoxin

Source ID Structure
AlphaFold DB A0A0M3DCF4

References