Detailed information of TA system TA109183

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 1667552..1668609
• Replicon: chromosome
• Accession: NZ_CP031416
• Organism: Gallaecimonas mangrovi strain HK-28

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DW350_RS07950
• Protein ID: WP_115718352.1
• Coordinates: 1667902..1668609 (+)
• Length: 236 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DW350_RS07945
• Protein ID: WP_115718351.1
• Coordinates: 1667552..1667902 (+)
• Length: 117 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DW350_RS07925	1662599..1663729	-	1131	WP_115718347.1	N-acetylglucosamine-6-phosphate deacetylase	-
DW350_RS07930	1663810..1665468	+	1659	WP_115718348.1	glutamine--tRNA ligase	-
DW350_RS07935	1665607..1666161	+	555	WP_115718349.1	NAD(P)H nitroreductase	-
DW350_RS07940	1666364..1667500	+	1137	WP_115718350.1	MFS transporter	-
DW350_RS07945	1667552..1667902	+	351	WP_115718351.1	XRE family transcriptional regulator	Antitoxin
DW350_RS07950	1667902..1668609	+	708	WP_115718352.1	RES family NAD+ phosphorylase	Toxin
DW350_RS07955	1668632..1670368	-	1737	WP_115718353.1	M1 family metallopeptidase	-
DW350_RS07960	1670570..1671760	+	1191	WP_115718354.1	MFS transporter	-
DW350_RS07965	1671737..1672216	-	480	WP_115718355.1	putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase	-
DW350_RS07970	1672379..1673203	+	825	WP_115718356.1	DNA ligase	-
DW350_RS07975	1673255..1673464	-	210	WP_115718357.1	cold-shock protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (51-194)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (4-61)

Sequences

Toxin

Protein

• Length: 236 a.a.
• Molecular weight: 27021.69 Da
• Isoelectric Point: 6.1512

>T109183 WP_115718352.1 NZ_CP031416:1667902-1668609 [Gallaecimonas mangrovi]
MHAIQGMGWRLVESQEQVATSQLVDSLAEQQLLEDLLDYAKPPRLPGTESLHYLLATPFRYPPLRWGSRFGRPHEPSLFY
GGKTINVTLTEGAYYRLVFYHSMATPPPGELLRTQHSLFAFYYRTELGEKLQDRPEQEALTDPADYRYCQQLGSELRQLG
VEAFEYRSARCPDQELNVALFTPKALLSKRPRRQTRWLCEVGPHGVSFLGGEGNDLYLFPLEMFWHNGQLPMPAE

Nucleotide

• Length: 708 bp

>T109183 NZ_CP031416:1667902-1668609 [Gallaecimonas mangrovi]
ATGCACGCTATCCAAGGAATGGGCTGGCGTTTAGTGGAATCGCAAGAACAAGTTGCCACATCACAATTGGTTGATAGTCT
GGCCGAGCAGCAATTGCTGGAAGACTTACTCGATTACGCCAAGCCGCCACGACTACCCGGTACTGAAAGTCTGCATTACT
TACTGGCCACACCTTTTCGTTACCCGCCGCTGCGCTGGGGCTCCCGTTTTGGTCGCCCTCACGAACCTAGCCTGTTTTAT
GGTGGTAAAACCATCAATGTTACCCTGACCGAAGGGGCTTACTACCGGCTGGTTTTTTATCATTCCATGGCCACGCCGCC
ACCTGGTGAGCTGCTTCGCACCCAGCACAGCCTGTTTGCCTTTTATTACCGCACCGAGCTAGGTGAAAAGTTACAAGACC
GGCCTGAGCAAGAGGCGCTAACTGACCCTGCTGATTATCGCTATTGCCAGCAATTGGGTAGCGAGCTTCGCCAGCTAGGT
GTTGAGGCCTTTGAATACCGCTCAGCGCGTTGCCCCGACCAAGAGCTTAATGTGGCGCTGTTTACGCCAAAGGCGCTATT
AAGTAAAAGGCCGCGCCGACAAACGCGCTGGCTATGTGAAGTTGGCCCCCATGGCGTGAGCTTTCTTGGCGGTGAGGGCA
ATGACTTATATCTGTTCCCACTCGAGATGTTTTGGCACAACGGTCAGTTACCGATGCCAGCTGAATAA

Antitoxin

Protein

• Length: 117 a.a.
• Molecular weight: 12470.58 Da
• Isoelectric Point: 10.7722

>AT109183 WP_115718351.1 NZ_CP031416:1667552-1667902 [Gallaecimonas mangrovi]
MQAVAQLDPKSVLSKAVLNAGKDLGLTQVEIGTVIGRNRTRLRDGIEPASKEGELALLLVRLHRSLFALTGGQSADMKHF
MVTHNHLSQGVPKEQVASVQGLVKLVNLLDGLRGKI

Nucleotide

• Length: 351 bp

>AT109183 NZ_CP031416:1667552-1667902 [Gallaecimonas mangrovi]
ATGCAAGCGGTTGCTCAGCTCGACCCGAAAAGCGTACTTAGTAAAGCCGTATTGAATGCCGGTAAAGACTTGGGGTTAAC
CCAGGTTGAAATTGGCACTGTGATTGGCCGTAACCGAACGCGCTTGCGAGACGGTATTGAACCTGCCAGCAAAGAAGGCG
AACTGGCGCTGCTGTTAGTGCGCCTTCATCGCAGCCTGTTTGCACTTACCGGCGGCCAAAGTGCGGATATGAAGCACTTT
ATGGTGACCCATAATCATCTAAGCCAAGGGGTGCCGAAAGAGCAGGTTGCATCGGTGCAAGGTTTGGTAAAGTTGGTGAA
CTTGCTTGATGGCCTTAGGGGCAAAATTTAA