Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 150176..150720 Replicon chromosome
Accession NZ_CP031415
Organism Saccharospirillum mangrovi strain HK-33

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DW349_RS00765 Protein ID WP_108125776.1
Coordinates 150421..150720 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DW349_RS00760 Protein ID WP_108125775.1
Coordinates 150176..150433 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DW349_RS00730 145943..146425 - 483 WP_157954357.1 oxidoreductase -
DW349_RS00735 146493..147008 - 516 WP_108125771.1 DNA-deoxyinosine glycosylase -
DW349_RS00740 147175..148674 + 1500 WP_108125772.1 carboxypeptidase M32 -
DW349_RS00745 148671..149162 + 492 WP_198650497.1 GNAT family N-acetyltransferase -
DW349_RS00750 149175..149612 + 438 WP_108125773.1 GNAT family N-acetyltransferase -
DW349_RS00755 149655..150104 + 450 WP_108125774.1 GNAT family N-acetyltransferase -
DW349_RS00760 150176..150433 + 258 WP_108125775.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DW349_RS00765 150421..150720 + 300 WP_108125776.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DW349_RS00770 150746..150964 - 219 WP_108125777.1 hypothetical protein -
DW349_RS00775 150978..151406 + 429 WP_108125778.1 DUF4440 domain-containing protein -
DW349_RS00780 151409..153574 - 2166 WP_108125779.1 DNA helicase II -
DW349_RS00785 153654..154196 - 543 WP_108125780.1 hypothetical protein -
DW349_RS00790 154356..154628 + 273 WP_108125894.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11259.05 Da        Isoelectric Point: 4.2472

>T109181 WP_108125776.1 NZ_CP031415:150421-150720 [Saccharospirillum mangrovi]
MAEIVWTEPALQQLDDIAEYIALDKPNAAGQLVASVFEEVERLAGFPQSGRIPPELPGSVYREVVVPPCRVFYRIEATTV
IILLVIREEQLFRRFMLDN

Download         Length: 300 bp

>T109181 NZ_CP031415:150421-150720 [Saccharospirillum mangrovi]
ATGGCTGAAATAGTCTGGACGGAACCCGCGCTTCAACAATTGGACGACATCGCAGAATACATCGCACTGGATAAACCTAA
CGCGGCCGGCCAATTGGTTGCCTCAGTTTTTGAAGAAGTGGAACGCCTGGCAGGTTTCCCACAATCGGGCCGAATACCGC
CCGAGCTGCCGGGTTCGGTATATAGGGAAGTGGTTGTGCCGCCTTGTCGTGTGTTTTATCGAATTGAAGCTACAACGGTT
ATTATTCTGTTGGTGATCAGGGAGGAGCAGTTATTTCGTCGATTCATGCTCGACAATTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9720.27 Da        Isoelectric Point: 9.6561

>AT109181 WP_108125775.1 NZ_CP031415:150176-150433 [Saccharospirillum mangrovi]
MKVELVTNLKRQATKILADLHSSKEPVLITEHGQPSAYLVDVQDYELMQRRLALLDGLSRGERAAMEGRTLNQTEAREKM
AKWLK

Download         Length: 258 bp

>AT109181 NZ_CP031415:150176-150433 [Saccharospirillum mangrovi]
ATGAAAGTCGAACTGGTCACCAACCTCAAACGCCAGGCCACCAAGATCCTGGCGGATCTCCATTCATCTAAAGAGCCGGT
GTTGATCACTGAACATGGCCAGCCCTCCGCCTATCTGGTTGACGTTCAGGATTATGAATTGATGCAGCGCCGCTTGGCGC
TTTTGGATGGATTATCTCGTGGCGAACGTGCCGCTATGGAAGGCCGCACACTGAACCAAACAGAAGCCAGGGAGAAAATG
GCTAAATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References