Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 6463290..6464545 Replicon chromosome
Accession NZ_CP031396
Organism Pseudomonas protegens strain FD6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DWF74_RS29445 Protein ID WP_115582311.1
Coordinates 6463973..6464545 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DWF74_RS29440 Protein ID WP_178116115.1
Coordinates 6463290..6463847 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWF74_RS29405 6458381..6458491 + 111 Protein_5742 AsnC family transcriptional regulator -
DWF74_RS29410 6458563..6458775 + 213 WP_115582307.1 DUF3079 domain-containing protein -
DWF74_RS29415 6458855..6459508 + 654 Protein_5744 DUF2239 family protein -
DWF74_RS29420 6459628..6460248 - 621 WP_102864513.1 LysE family translocator -
DWF74_RS29425 6460489..6461076 - 588 WP_102864514.1 inclusion body family protein -
DWF74_RS29430 6461436..6462632 + 1197 WP_115582308.1 PrpF protein -
DWF74_RS29435 6462759..6463100 - 342 WP_115582309.1 low molecular weight protein tyrosine phosphatase family protein -
DWF74_RS29440 6463290..6463847 + 558 WP_178116115.1 helix-turn-helix domain-containing protein Antitoxin
DWF74_RS29445 6463973..6464545 + 573 WP_115582311.1 HD domain-containing protein Toxin
DWF74_RS29450 6464803..6466983 + 2181 WP_115582312.1 catalase/peroxidase HPI -
DWF74_RS29455 6467199..6467627 - 429 WP_115582313.1 hypothetical protein -
DWF74_RS29460 6467850..6468113 + 264 WP_102864520.1 hypothetical protein -
DWF74_RS29465 6468110..6468304 + 195 WP_115582314.1 hypothetical protein -
DWF74_RS29470 6468351..6469019 - 669 WP_115582315.1 phytanoyl-CoA dioxygenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-47)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21513.07 Da        Isoelectric Point: 4.8382

>T109179 WP_115582311.1 NZ_CP031396:6463973-6464545 [Pseudomonas protegens]
MTPELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQYLARSLDAPARQRLLELWDEYEGAASTEARAVKALDKLETLLQHTQGQNPADFDYGFNLDY
GRRYTDASPLFQALRQQIDADTRRRLDAQG

Download         Length: 573 bp

>T109179 NZ_CP031396:6463973-6464545 [Pseudomonas protegens]
ATGACCCCCGAACTTCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTTTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGTTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAAGCCATCCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAACAGGAACGCGACGACCTGCAATACCTCGCCCGGTCCCTGGACGC
CCCGGCCCGCCAGCGCCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCACCGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGATTTCGACTACGGTTTCAACCTCGATTAC
GGCCGCCGCTACACCGATGCCAGCCCGTTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCGGCGCCGCCTCGA
CGCCCAGGGCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20358.33 Da        Isoelectric Point: 7.8013

>AT109179 WP_178116115.1 NZ_CP031396:6463290-6463847 [Pseudomonas protegens]
MSAALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEHLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAAQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWRAVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT109179 NZ_CP031396:6463290-6463847 [Pseudomonas protegens]
ATGTCCGCAGCCCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCTGCCGAGCTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAGGCCATGGAACCGGCGG
AGCGTGCGCGCCTGGAGCACCTGCTGGCGGCCAACCTCAGCGCCGCTGCCGATCAGGCCCTGGCGCGGCTGGTGAACGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGCGCAGTTCGG
CGTGCCCTTGAGCGAGCTGCTGGGCCAATCGCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGCAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCTCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References