Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 4279136..4279732 Replicon chromosome
Accession NZ_CP031396
Organism Pseudomonas protegens strain FD6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DWF74_RS19285 Protein ID WP_115581506.1
Coordinates 4279430..4279732 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DWF74_RS19280 Protein ID WP_115581505.1
Coordinates 4279136..4279426 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWF74_RS19260 4275408..4277540 - 2133 WP_115581502.1 TonB-dependent copper receptor -
DWF74_RS19265 4277629..4278075 - 447 WP_102862975.1 DUF2946 domain-containing protein -
DWF74_RS19270 4278094..4278573 - 480 WP_205413510.1 copper chaperone PCu(A)C -
DWF74_RS19275 4278638..4279036 - 399 WP_115581504.1 DUF2946 domain-containing protein -
DWF74_RS19280 4279136..4279426 - 291 WP_115581505.1 putative addiction module antidote protein Antitoxin
DWF74_RS19285 4279430..4279732 - 303 WP_115581506.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DWF74_RS19290 4279906..4280634 - 729 WP_115581507.1 cobalt-precorrin-6A reductase -
DWF74_RS19295 4280631..4281728 - 1098 WP_102862980.1 cobalt-precorrin-5B (C(1))-methyltransferase -
DWF74_RS19300 4281822..4283036 - 1215 WP_115581508.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
DWF74_RS19305 4283168..4284481 + 1314 WP_115581509.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-97)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11644.38 Da        Isoelectric Point: 10.2805

>T109176 WP_115581506.1 NZ_CP031396:c4279732-4279430 [Pseudomonas protegens]
MYVFEQTLEFSRWLLHLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVYEMHIHRGPGYRVYFSRRGTVIYLLLIGGDKN
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T109176 NZ_CP031396:c4279732-4279430 [Pseudomonas protegens]
ATGTACGTCTTCGAGCAGACCCTGGAGTTCAGCCGCTGGCTCCTGCACCTGAAGGATCCGCAAGGCAAAACCCGTGTACT
GGCCAGGATCCGCGCCGCCCAACTGGGCCGATTCGGCGACTGCGAACCGGTGGGCGAAGGTGTCTATGAAATGCACATCC
ATCGCGGCCCCGGCTATCGGGTGTACTTCTCGCGCCGGGGCACGGTGATCTACCTGTTGTTGATCGGCGGTGACAAGAAC
ACCCAGAGACGCGATATCCAACGCGCCAGGCAACTGGCCCACGACCTCAAGAGCGAGGGTTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10467.01 Da        Isoelectric Point: 6.4594

>AT109176 WP_115581505.1 NZ_CP031396:c4279426-4279136 [Pseudomonas protegens]
MHTPVTRFDAAEYLKNPEDMVAYLDACFEEDTGDGKLIRAALNDIARARGMTQIARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLHVSPA

Download         Length: 291 bp

>AT109176 NZ_CP031396:c4279426-4279136 [Pseudomonas protegens]
ATGCACACCCCAGTCACCCGCTTCGACGCGGCGGAGTACCTCAAGAACCCTGAAGACATGGTGGCCTACCTCGACGCCTG
CTTCGAGGAAGACACCGGCGATGGCAAGCTGATCCGCGCCGCCCTCAACGACATCGCCCGCGCCCGCGGCATGACCCAGA
TCGCCCGCGATACCGGCCTGGGTCGCGAGAGCCTGTACAAGGCCCTGGGCAGCCAGGGCAATCCCGAGTTCGCGACTATC
ATCAAGGTCATGAAGGCACTGGGACTCAAGCTCCACGTCAGCCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References