Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 3407643..3409351 Replicon chromosome
Accession NZ_CP031396
Organism Pseudomonas protegens strain FD6

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag DWF74_RS15385 Protein ID WP_102862339.1
Coordinates 3407643..3408521 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag DWF74_RS15390 Protein ID WP_102862340.1
Coordinates 3408518..3409351 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWF74_RS15360 3403627..3404478 + 852 WP_102862336.1 ABC transporter ATP-binding protein -
DWF74_RS15365 3404518..3405519 + 1002 WP_115581235.1 ABC transporter substrate-binding protein -
DWF74_RS15370 3405549..3406325 + 777 WP_115581236.1 ABC transporter permease -
DWF74_RS15375 3406325..3407089 + 765 WP_102862533.1 SDR family oxidoreductase -
DWF74_RS15380 3407102..3407638 + 537 WP_060845001.1 cupin domain-containing protein -
DWF74_RS15385 3407643..3408521 + 879 WP_102862339.1 alpha/beta hydrolase Toxin
DWF74_RS15390 3408518..3409351 + 834 WP_102862340.1 IclR family transcriptional regulator Antitoxin
DWF74_RS15395 3409353..3410150 + 798 WP_102862341.1 SDR family oxidoreductase -
DWF74_RS15400 3410143..3411825 + 1683 WP_115581237.1 thiamine pyrophosphate-binding protein -
DWF74_RS15405 3411836..3412639 + 804 WP_115581238.1 aspartate dehydrogenase -
DWF74_RS15410 3412746..3414242 + 1497 WP_115581239.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30747.46 Da        Isoelectric Point: 8.7608

>T109173 WP_102862339.1 NZ_CP031396:3407643-3408521 [Pseudomonas protegens]
MFPGLSQPAATADLKAQLARDFPQRLVTASGGRQALREGGAGPALVLLHGIGSGAASWLEVAQHLAPKARVIAWDAPGYG
DSSPLEPPAPKAEHYAARLLQMLDALQIEQCVLVGHSLGALPALALARSTQARRVSRLLLISPARGYGAPALAEQGRQVR
QQRLDTLERLGIAGLAEQRSAQMLSPSATPQALAWVRWNMARLNPAGYRQAIELLCGDDLLRHGPPGMPCEVHCGAADRI
TPAEGCRTLAKALGARFNLIADAGHASPVEQPLVVAGRLACAIEESLTGRPL

Download         Length: 879 bp

>T109173 NZ_CP031396:3407643-3408521 [Pseudomonas protegens]
ATGTTCCCAGGCCTCTCTCAACCGGCAGCGACGGCGGACCTGAAAGCCCAGCTGGCCCGGGACTTTCCCCAGCGCCTGGT
GACGGCCAGCGGTGGCCGCCAGGCCCTGCGTGAAGGCGGCGCGGGGCCGGCGCTGGTGCTGCTGCACGGCATCGGCTCCG
GGGCGGCCTCCTGGCTGGAAGTCGCACAGCACCTGGCGCCCAAGGCCCGGGTCATTGCCTGGGACGCGCCCGGCTACGGT
GACTCCAGCCCGCTGGAACCCCCCGCGCCGAAAGCCGAGCACTACGCCGCCCGGCTGCTGCAGATGCTCGATGCGCTGCA
GATCGAGCAATGCGTGCTGGTGGGGCACTCCCTGGGCGCGTTGCCGGCCCTGGCCCTGGCTCGCAGCACCCAGGCCCGGC
GGGTCAGCCGCTTGCTGCTGATCAGCCCGGCCCGGGGCTACGGCGCGCCAGCGCTGGCCGAGCAGGGCCGGCAGGTGCGT
CAACAACGCCTGGACACGCTAGAGCGCCTGGGCATCGCCGGCCTGGCCGAACAGCGCAGCGCCCAGATGCTCTCGCCCTC
CGCCACGCCCCAGGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTGAACCCTGCCGGGTATCGCCAGGCCATCGAGC
TGCTGTGCGGCGACGATCTGCTGCGCCATGGCCCACCCGGCATGCCCTGCGAAGTGCATTGCGGCGCAGCCGACCGCATC
ACCCCGGCCGAGGGTTGCCGGACCCTGGCCAAGGCGCTGGGCGCGCGCTTCAACCTGATCGCCGACGCGGGCCACGCCAG
CCCCGTCGAACAACCGCTGGTGGTGGCGGGCCGCCTGGCCTGCGCCATCGAAGAATCCCTGACAGGTAGACCCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30446.93 Da        Isoelectric Point: 6.9725

>AT109173 WP_102862340.1 NZ_CP031396:3408518-3409351 [Pseudomonas protegens]
MNDADPLKDPQDKYIVPGLERGLLLLCEFSRSNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVSVGTRLPAHATVLGRVLLGDLSLA
ELRELYPEEHLEQHSPSTPNTVMALFDMVQADRQRGFVSGEGFFEPSISTVAAPVRDQSGSIVAALGVTIATAQVGHINY
NELLLQVRRSADELSRLLNYNSAAHNGLPRVTALMRD

Download         Length: 834 bp

>AT109173 NZ_CP031396:3408518-3409351 [Pseudomonas protegens]
ATGAACGACGCCGATCCGCTGAAGGACCCTCAGGACAAATACATAGTCCCGGGCCTGGAACGGGGCCTGTTGCTGCTGTG
CGAGTTCAGCCGCAGCAACCGCACCCTCACTGCCCCGGAGCTGGCCCGGCGCCTGGCCCTGCCGCGCTCGACCATCTTCC
GTCTGCTGACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTGCTGCGC
CTGGGCTTCGAATACCTGGCGTCGCTGGAGCTCACCGAGCTGGGCCAGCCACTGCTGGCGCGGCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTCTACGTGGCCAAGGTTTCGCCACCTTCGGTGTTCTCCA
GCGCGGTCAGTGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTCGGCCGCGTGCTGCTGGGGGATTTGTCCCTGGCC
GAGCTGCGCGAGCTGTACCCGGAGGAACACCTGGAACAGCACTCCCCCAGCACGCCAAACACCGTGATGGCGCTGTTCGA
CATGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGCGGCGAAGGGTTCTTCGAGCCGAGCATTTCCACGGTGGCGGCCC
CGGTGCGTGATCAGAGCGGCAGCATCGTCGCCGCCTTAGGAGTGACCATCGCCACCGCCCAGGTCGGCCACATCAACTAC
AACGAACTGCTGCTGCAGGTACGCCGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACAACAGCGCCGCCCACAACGG
GCTGCCGCGGGTCACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References