Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1099755..1101484 Replicon chromosome
Accession NZ_CP031396
Organism Pseudomonas protegens strain FD6

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag DWF74_RS04620 Protein ID WP_115580471.1
Coordinates 1099755..1100399 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag DWF74_RS04625 Protein ID WP_115580472.1
Coordinates 1100396..1101484 (+) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWF74_RS04600 1095877..1096857 + 981 Protein_914 type I restriction endonuclease subunit R -
DWF74_RS04605 1097113..1097559 + 447 Protein_915 winged helix-turn-helix domain-containing protein -
DWF74_RS04610 1097919..1098806 - 888 WP_162884073.1 helix-turn-helix domain-containing protein -
DWF74_RS04615 1099186..1099758 + 573 WP_115580470.1 DUF4433 domain-containing protein -
DWF74_RS04620 1099755..1100399 + 645 WP_115580471.1 DUF4433 domain-containing protein Toxin
DWF74_RS04625 1100396..1101484 + 1089 WP_115580472.1 macro domain-containing protein Antitoxin
DWF74_RS04630 1101568..1103601 - 2034 WP_115580473.1 sulfatase-like hydrolase/transferase -
DWF74_RS04635 1103651..1104262 - 612 WP_115580474.1 hypothetical protein -
DWF74_RS04640 1104262..1105557 - 1296 WP_115580475.1 exo-alpha-sialidase -
DWF74_RS04645 1105601..1106146 - 546 WP_115580476.1 cytochrome b/b6 domain-containing protein -
DWF74_RS04650 1106146..1106412 - 267 WP_060840094.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24870.51 Da        Isoelectric Point: 8.4285

>T109171 WP_115580471.1 NZ_CP031396:1099755-1100399 [Pseudomonas protegens]
MNYSRLNPEKALIWRIVHRDNLPWILDNGLHCASSEIQAPQYVNIGNVDLIDKRRARHVPITPGGVLADYVPFYFTPFSV
MMKNIHSGRSVQQRTNDEIVILVSSLYRVEQLGLPFVFTNAHAYPYWTDYYSDLANLSQVDWAILQRRDFKRDPDDPRKM
ERYQAEALIHNHLPITGLLGIMCYSDAMKKRIEQDLATRGLALPVHARPGWYFQ

Download         Length: 645 bp

>T109171 NZ_CP031396:1099755-1100399 [Pseudomonas protegens]
ATGAATTACAGCAGACTGAATCCAGAGAAGGCTCTGATTTGGCGTATCGTCCATCGCGACAACCTGCCTTGGATTCTGGA
CAACGGTCTGCATTGTGCGAGCTCCGAAATACAGGCCCCCCAGTACGTAAACATCGGCAACGTAGACCTGATCGACAAGC
GCCGGGCACGTCATGTACCCATTACTCCTGGTGGTGTGCTAGCTGATTATGTGCCCTTCTATTTCACTCCTTTCTCTGTG
ATGATGAAAAACATTCACTCAGGCCGGAGTGTTCAACAACGCACCAATGATGAGATTGTGATTCTGGTATCGAGCTTGTA
CCGCGTCGAACAGCTAGGACTACCGTTCGTCTTCACAAACGCACACGCCTATCCGTATTGGACAGACTATTACAGCGATC
TGGCGAATCTCAGCCAGGTCGACTGGGCTATCCTTCAGCGACGCGACTTCAAACGCGACCCCGATGACCCTAGAAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACAATCACCTACCGATTACAGGACTCCTCGGCATCATGTGCTACAGCGATGC
AATGAAGAAACGCATAGAACAAGACTTGGCCACCAGAGGTTTGGCCTTGCCTGTTCATGCGCGTCCGGGATGGTATTTCC
AATGA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40804.96 Da        Isoelectric Point: 7.0357

>AT109171 WP_115580472.1 NZ_CP031396:1100396-1101484 [Pseudomonas protegens]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFSENYRLYSAACKAGAVETGKMHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENQVKSVAVPPLGAGNGGLKWPEVREQIVSILSDLDVDILVFEPSKQYLNVAKRNG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPDTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CNKRISDADISDVIWFDDVRKTFLQTYLKTEAKEYAQALERTAELIDGFESPFGMELLATVDWLLNREGVSPTVPAVREA
LKQWDGGAGSAARKNRLFDDQALDIALKRLTSSSFSPELAVC

Download         Length: 1089 bp

>AT109171 NZ_CP031396:1100396-1101484 [Pseudomonas protegens]
ATGATCCGTTTTACCCAAGGCAACCTTCTGGAAGCCAAAACCGAAGCCCTGGTCAACACGGTGAATACCGTAGGCGTGAT
GGGCAAAGGAATCGCTCTGATGTTTAAAGAGCGTTTTAGCGAGAATTACCGTCTGTACTCGGCAGCCTGCAAAGCTGGCG
CGGTGGAGACTGGCAAAATGCACGTCACCGCCGTCAACGAGTTGGATGGACCACGTTGGATCGTGAACTTCCCTACCAAG
CGTCACTGGCGATCACCCTCGCAGATGGCTTGGATAACAGAAGGTTTGCATGACCTGCGTCGTTTTTTGCTTGAAAACCA
GGTGAAGTCCGTCGCAGTGCCTCCGCTAGGTGCCGGTAACGGTGGCTTGAAATGGCCTGAAGTTCGGGAGCAGATCGTTT
CGATACTCAGCGATCTGGATGTCGATATTTTGGTGTTTGAGCCTTCTAAACAGTATCTGAACGTCGCCAAACGAAACGGA
GTGGAGAAACTCACGCCCGCTCGCGCGCTGATTGCAGAACTGGTTAGGCGTTACTGGGTTTTAGGCATGGAGTGCAGTCT
GCTAGAAATTCAGAAACTCGCTTGGTTCCTTGAGCGAGCAATAGAAAAACTGCCAGACACCGAGAACCCTTTAAACCTTA
AATTTGTTGCTCACAAATTTGGGCCATATGCCAACCGCTTGGAGCATTTGCTGAATAATCTGGATGGCAGCTATCTGCAC
TGCAACAAGCGAATCAGTGACGCCGATATTAGCGATGTGATCTGGTTCGACGATGTGCGTAAGACTTTTCTACAGACCTA
TCTCAAAACCGAAGCAAAAGAGTACGCCCAAGCATTGGAGCGCACCGCTGAGCTGATTGACGGTTTTGAATCTCCCTTTG
GCATGGAGCTGTTGGCGACGGTCGATTGGTTACTAAACCGAGAAGGGGTTTCTCCAACTGTTCCCGCAGTGCGCGAGGCA
TTGAAGCAGTGGGACGGAGGGGCCGGCTCTGCTGCTCGCAAGAACAGGCTGTTCGACGATCAGGCGCTTGATATAGCGCT
CAAACGCCTGACGTCCAGTAGCTTCAGTCCTGAACTGGCTGTCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References