Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-DnaT |
Location | 27971..28493 | Replicon | plasmid p2 |
Accession | NZ_CP031361 | ||
Organism | Salmonella enterica subsp. enterica serovar Heidelberg strain 5 |
Toxin (Protein)
Gene name | relE | Uniprot ID | G3CAN5 |
Locus tag | DXF95_RS23760 | Protein ID | WP_000220560.1 |
Coordinates | 28212..28493 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | G3CAG1 |
Locus tag | DXF95_RS23755 | Protein ID | WP_000121743.1 |
Coordinates | 27971..28222 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DXF95_RS23725 | 23642..23923 | + | 282 | WP_001185482.1 | hypothetical protein | - |
DXF95_RS23730 | 23948..24925 | + | 978 | WP_001269910.1 | hypothetical protein | - |
DXF95_RS23735 | 24922..25347 | - | 426 | WP_000202944.1 | hypothetical protein | - |
DXF95_RS23740 | 25415..25861 | - | 447 | WP_001074386.1 | hypothetical protein | - |
DXF95_RS23745 | 25901..26737 | - | 837 | WP_001050931.1 | replication initiation protein | - |
DXF95_RS23755 | 27971..28222 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin |
DXF95_RS23760 | 28212..28493 | + | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
DXF95_RS23765 | 28639..28962 | + | 324 | WP_001181903.1 | hypothetical protein | - |
DXF95_RS23770 | 29007..29252 | + | 246 | WP_000356547.1 | hypothetical protein | - |
DXF95_RS23775 | 29242..29457 | + | 216 | WP_001180116.1 | hypothetical protein | - |
DXF95_RS23780 | 29550..29879 | + | 330 | WP_000866646.1 | hypothetical protein | - |
DXF95_RS23785 | 29922..30101 | + | 180 | WP_000439078.1 | hypothetical protein | - |
DXF95_RS23790 | 30171..30320 | + | 150 | WP_000003880.1 | hypothetical protein | - |
DXF95_RS23795 | 30333..30605 | + | 273 | WP_000160399.1 | hypothetical protein | - |
DXF95_RS25155 | 30862..30936 | + | 75 | Protein_37 | DNA distortion polypeptide 3 | - |
DXF95_RS23800 | 30931..31476 | + | 546 | WP_000757693.1 | hypothetical protein | - |
DXF95_RS23805 | 31479..32645 | + | 1167 | WP_000539532.1 | relaxase/mobilization nuclease domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..37697 | 37697 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 12066.38 Da Isoelectric Point: 12.7685
>T109144 WP_000220560.1 NZ_CP031361:28212-28493 [Salmonella enterica subsp. enterica serovar Heidelberg]
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Download Length: 282 bp
>T109144 NZ_CP031361:28212-28493 [Salmonella enterica subsp. enterica serovar Heidelberg]
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Antitoxin
Download Length: 84 a.a. Molecular weight: 10784.64 Da Isoelectric Point: 12.7191
>AT109144 WP_000121743.1 NZ_CP031361:27971-28222 [Salmonella enterica subsp. enterica serovar Heidelberg]
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KKKK
Download Length: 252 bp
>AT109144 NZ_CP031361:27971-28222 [Salmonella enterica subsp. enterica serovar Heidelberg]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
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AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
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Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | G3CAN5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5I301 |