Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2196812..2197350 Replicon chromosome
Accession NZ_CP031357
Organism Erythrobacter aureus strain YH-07

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DVR09_RS10730 Protein ID WP_115416921.1
Coordinates 2197060..2197350 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DVR09_RS10725 Protein ID WP_115416920.1
Coordinates 2196812..2197063 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVR09_RS10690 2192187..2192831 + 645 WP_115416914.1 peptidylprolyl isomerase -
DVR09_RS10695 2192839..2193114 - 276 WP_115416915.1 DUF1971 domain-containing protein -
DVR09_RS10700 2193111..2193560 - 450 WP_115416916.1 hypothetical protein -
DVR09_RS10705 2193553..2194032 - 480 WP_115416917.1 group III truncated hemoglobin -
DVR09_RS10710 2194116..2194550 + 435 WP_115417908.1 Rrf2 family transcriptional regulator -
DVR09_RS10715 2194557..2195420 - 864 WP_115416918.1 glycoside hydrolase -
DVR09_RS10720 2195429..2196736 - 1308 WP_115416919.1 M20/M25/M40 family metallo-hydrolase -
DVR09_RS10725 2196812..2197063 + 252 WP_115416920.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
DVR09_RS10730 2197060..2197350 + 291 WP_115416921.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DVR09_RS10735 2197430..2199274 - 1845 WP_115416922.1 succinate dehydrogenase flavoprotein subunit -
DVR09_RS10740 2199274..2199660 - 387 WP_115416923.1 succinate dehydrogenase, hydrophobic membrane anchor protein -
DVR09_RS10745 2199670..2200050 - 381 WP_115416924.1 succinate dehydrogenase, cytochrome b556 subunit -
DVR09_RS10750 2200256..2200966 + 711 WP_115416925.1 SDR family oxidoreductase -
DVR09_RS10755 2200956..2201867 + 912 WP_115416926.1 subclass B3 metallo-beta-lactamase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(3-81)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11274.86 Da        Isoelectric Point: 5.1181

>T109143 WP_115416921.1 NZ_CP031357:2197060-2197350 [Erythrobacter aureus]
MMQFRLRDAARRDLAEIWLTTAERWGIDQADDYVRALEDCLLRICDFPASYPNYEGCHGTFRKALSGEHLIFYRVGQQVI
DVARILHNRMDVEDIL

Download         Length: 291 bp

>T109143 NZ_CP031357:2197060-2197350 [Erythrobacter aureus]
ATGATGCAATTCCGCCTGCGCGACGCGGCGAGGCGCGACCTTGCGGAAATCTGGCTAACCACCGCCGAACGCTGGGGCAT
CGATCAGGCCGACGACTATGTTCGGGCTCTTGAGGATTGCCTCCTACGCATCTGCGATTTCCCAGCGAGCTATCCGAACT
ACGAGGGTTGCCACGGAACCTTTCGCAAGGCCCTGAGCGGAGAGCACCTGATCTTCTATCGGGTTGGCCAGCAGGTGATC
GACGTCGCCCGCATCCTGCACAACCGCATGGATGTAGAGGATATCCTCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9350.53 Da        Isoelectric Point: 8.4589

>AT109143 WP_115416920.1 NZ_CP031357:2196812-2197063 [Erythrobacter aureus]
MAAKNTSIALGKPYTDFARKKVESGEFATTSEVVREAMRQYIAQDTKREALDRALKEGLDSGPARPFDFDGFLRDMRANY
KAE

Download         Length: 252 bp

>AT109143 NZ_CP031357:2196812-2197063 [Erythrobacter aureus]
ATGGCCGCCAAGAATACCTCTATCGCCTTGGGTAAACCCTATACCGATTTCGCTCGCAAAAAGGTCGAAAGCGGCGAGTT
CGCCACCACCAGCGAAGTGGTGCGCGAAGCGATGCGGCAGTACATCGCGCAGGATACCAAACGCGAAGCGCTGGACCGCG
CGCTGAAAGAAGGGCTCGACAGCGGGCCTGCCCGGCCATTCGATTTCGACGGCTTCCTCCGCGATATGCGGGCGAACTAC
AAAGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References