Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1742251..1742519 Replicon chromosome
Accession NZ_CP031355
Organism Escherichia coli O145 strain RM8995-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1742289..1742392 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1742251..1742519 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE49_RS08880 1739408..1740847 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DXE49_RS08885 1740965..1741201 + 237 WP_001295499.1 DUF1480 family protein -
DXE49_RS08890 1741306..1741497 + 192 WP_001313035.1 YebW family protein -
DXE49_RS08895 1741498..1742154 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 1742251..1742519 + 269 - - Antitoxin
- 1742289..1742392 - 104 - - Toxin
DXE49_RS08900 1742549..1742890 - 342 WP_000976475.1 YebY family protein -
DXE49_RS08905 1742903..1743775 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
DXE49_RS08910 1743779..1744153 - 375 WP_000168738.1 CopC domain-containing protein YobA -
DXE49_RS08915 1744292..1744522 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DXE49_RS08920 1744624..1745280 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
DXE49_RS08925 1745304..1745966 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T109122 NZ_CP031355:c1742392-1742289 [Escherichia coli O145]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT109122 NZ_CP031355:1742251-1742519 [Escherichia coli O145]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References