Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4706410..4707002 Replicon chromosome
Accession NZ_CP031316
Organism Serratia marcescens strain N4-5

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag Smn45_RS22700 Protein ID WP_115436595.1
Coordinates 4706652..4707002 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag Smn45_RS22695 Protein ID WP_049300713.1
Coordinates 4706410..4706658 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Smn45_RS22675 4702230..4702568 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
Smn45_RS22680 4702565..4703872 + 1308 WP_115436594.1 6-phospho-beta-glucosidase -
Smn45_RS22685 4703943..4704923 + 981 WP_016930354.1 LacI family transcriptional regulator -
Smn45_RS22690 4705115..4706299 + 1185 WP_004930336.1 MFS transporter TsgA -
Smn45_RS22695 4706410..4706658 + 249 WP_049300713.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
Smn45_RS22700 4706652..4707002 + 351 WP_115436595.1 type II toxin-antitoxin system ChpB family toxin Toxin
Smn45_RS22705 4706999..4708282 - 1284 WP_060441380.1 cytosine deaminase -
Smn45_RS22715 4708571..4711120 + 2550 WP_033639222.1 nitrite reductase large subunit NirB -
Smn45_RS22720 4711117..4711443 + 327 WP_115436596.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-116)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12370.39 Da        Isoelectric Point: 11.5657

>T108902 WP_115436595.1 NZ_CP031316:4706652-4707002 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDLRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T108902 NZ_CP031316:4706652-4707002 [Serratia marcescens]
ATGGTGAAGCGCCCCGTTTTTCAGCGCGGAGATCTTATCCGGGTCAGCCTGAATCCCGTGGTTGGCCGTGAGCAGCAAGG
CGACCTTCGTCCGGCACTGGTGCTCTCTCCCCGCGAGTTTAATGCGTTGGGCATGGTGCTGGTCGCCCCTATTTCGCAAG
GGGCTAATTTTGCCCGTACAGCGGGTTTCACCGTCAGCCTGAGCGGGAGCGGCACCGCAACGCAGGGCGTCATCTTGATC
AACCAGGTTCGCATGATGGATCTGGCCGGGCGCAGCGCGCAATTCATTGAACGTGCCCCTGGCGAAGTCATCGCCGACGC
GCTGGCGCGGCTTCAGGCAATCATCGACTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9069.53 Da        Isoelectric Point: 4.5026

>AT108902 WP_049300713.1 NZ_CP031316:4706410-4706658 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT108902 NZ_CP031316:4706410-4706658 [Serratia marcescens]
ATGAAAGTCTTTATCAAAAAATGGGGCAACAGCGCGGGAATGCTGGTGCCCTCAGCGCTAATGAACGAGCTGGAACTACA
GGTAGGTCAGGAAATGGACATGCAGGTCATCGATGGAGCGTTGGTCATTAAACCGGTTAAGAAACGCTATTCACTGCAGC
AATTGCTCGATGGCTGCGACGGTGAAGCGCCGGCCGCCGCAGACGACAACTGGGAACACATGCCGCCGGCGGGGAAAGAA
GTATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References