Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 902482..902995 Replicon chromosome
Accession NZ_CP031271
Organism Staphylococcus caprae strain 26D

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag DWB96_RS04225 Protein ID WP_172594642.1
Coordinates 902843..902995 (+) Length 51 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID A0A1S1GSV6
Locus tag DWB96_RS04220 Protein ID WP_037541856.1
Coordinates 902482..902775 (+) Length 98 a.a.

Genomic Context

DWB96_RS04195DWB96_RS04200DWB96_RS04205DWB96_RS04220DWB96_RS04225DWB96_RS04230DWB96_RS04240DWB96_RS04245DWB96_RS04210DWB96_RS04215DWB96_RS04235
Location: 897658..898452 (795 bp)
Type: Others
Protein ID: WP_002445553.1
Location: 898453..899091 (639 bp)
Type: Others
Protein ID: WP_002445552.1
Location: 899180..900049 (870 bp)
Type: Others
Protein ID: WP_044466357.1
Location: 902482..902775 (294 bp)
Type: Antitoxin
Protein ID: WP_037541856.1
Location: 902843..902995 (153 bp)
Type: Toxin
Protein ID: WP_172594642.1
Location: 903131..903268 (138 bp)
Type: Others
Protein ID: WP_002445543.1
Location: 905183..906253 (1071 bp)
Type: Others
Protein ID: WP_037541855.1
Location: 906269..907624 (1356 bp)
Type: Others
Protein ID: WP_002445538.1
Location: 900116..900766 (651 bp)
Type: Others
Protein ID: WP_044466356.1
Location: 900826..902310 (1485 bp)
Type: Others
Protein ID: WP_002445546.1
Location: 903325..904536 (1212 bp)
Type: Others
Protein ID: WP_002445542.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DWB96_RS04195897658..898452+795WP_002445553.1hydroxyethylthiazole kinase-
DWB96_RS04200898453..899091+639WP_002445552.1thiamine phosphate synthase-
DWB96_RS04205899180..900049+870WP_044466357.1membrane protein insertase YidC-
DWB96_RS04210900116..900766-651WP_044466356.1HD domain-containing protein-
DWB96_RS04215900826..902310-1485WP_002445546.1cardiolipin synthase-
DWB96_RS04220902482..902775+294WP_037541856.1copper-sensing transcriptional repressor CsoRAntitoxin
DWB96_RS04225902843..902995+153WP_172594642.1heavy-metal-associated domain-containing proteinToxin
DWB96_RS04230903131..903268+138WP_002445543.1hypothetical protein-
DWB96_RS04235903325..904536-1212WP_002445542.1rod shape-determining protein RodA-
DWB96_RS04240905183..906253+1071WP_037541855.1D-alanine--D-alanine ligase-
DWB96_RS04245906269..907624+1356WP_002445538.1UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(3-95)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5770.63 Da        Isoelectric Point: 4.2898

>T108809 WP_172594642.1 NZ_CP031271:902843-902995 [Staphylococcus caprae]
MLMERLQNMIGVYNVAIDSKVGEIKVEFDTPANLNSIEKEVYDSGYRILY

Download         Length: 153 bp

>T108809 NZ_CP031271:902843-902995 [Staphylococcus caprae]
ATGCTAATGGAACGTTTACAAAACATGATTGGCGTTTATAATGTGGCAATTGATAGTAAAGTAGGAGAAATAAAAGTCGA
GTTTGATACGCCTGCGAATTTAAATAGTATCGAAAAAGAGGTATATGATTCAGGTTATCGAATATTATATTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11078.60 Da        Isoelectric Point: 6.8620

>AT108809 WP_037541856.1 NZ_CP031271:902482-902775 [Staphylococcus caprae]
VTENEKAHHSDQTKANLKSRLNRIEGQVRAINRMIEDDVYCDDVLTQIRATRSALNSVATKLLDHHMKSCIMNKVNNGAQ
EEAMEELLVTFQKLIKD

Download         Length: 294 bp

>AT108809 NZ_CP031271:902482-902775 [Staphylococcus caprae]
GTGACTGAAAATGAAAAAGCACATCATTCAGATCAAACAAAAGCAAATTTAAAATCACGTTTAAACCGAATAGAAGGGCA
AGTTAGAGCAATTAATCGCATGATTGAAGACGACGTTTATTGTGATGATGTTTTAACTCAAATAAGAGCAACACGTTCAG
CACTCAATAGTGTAGCAACCAAGTTACTCGATCATCATATGAAAAGTTGTATCATGAACAAAGTGAACAATGGTGCACAA
GAAGAAGCAATGGAAGAATTATTAGTTACCTTTCAAAAATTAATTAAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1S1GSV6

References