Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2695557..2695825 Replicon chromosome
Accession NZ_CP031256
Organism Escherichia coli strain M16807

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2695685..2695787 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2695557..2695825 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DV447_RS13370 2692109..2692771 - 663 WP_000944256.1 exodeoxyribonuclease X -
DV447_RS13375 2692795..2693451 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
DV447_RS13380 2693554..2693784 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DV447_RS13385 2693923..2694297 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DV447_RS13390 2694301..2695173 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
DV447_RS13395 2695186..2695527 + 342 WP_000984819.1 YebY family protein -
- 2695557..2695825 - 269 - - Antitoxin
- 2695685..2695787 + 103 - - Toxin
DV447_RS13400 2695922..2696578 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
DV447_RS13405 2696579..2696770 - 192 WP_001317886.1 YebW family protein -
DV447_RS13410 2696875..2697111 - 237 WP_001295499.1 DUF1480 family protein -
DV447_RS13415 2697229..2698668 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T108748 NZ_CP031256:2695685-2695787 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT108748 NZ_CP031256:c2695825-2695557 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References