Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2491470..2491923 Replicon chromosome
Accession NZ_CP031255
Organism Neisseria elongata strain M15910

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DV445_RS12655 Protein ID WP_114922582.1
Coordinates 2491470..2491742 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DV445_RS12660 Protein ID WP_114922739.1
Coordinates 2491732..2491923 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DV445_RS12640 2488165..2490390 - 2226 WP_114922579.1 type IV secretory system conjugative DNA transfer family protein -
DV445_RS12645 2490461..2490862 - 402 WP_114922580.1 single-stranded DNA-binding protein -
DV445_RS12650 2490895..2491212 + 318 WP_114922581.1 hypothetical protein -
DV445_RS13085 2491143..2491382 - 240 WP_162817681.1 hypothetical protein -
DV445_RS12655 2491470..2491742 - 273 WP_114922582.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DV445_RS12660 2491732..2491923 - 192 WP_114922739.1 hypothetical protein Antitoxin
DV445_RS12665 2492030..2493151 - 1122 WP_114922583.1 Flp pilus assembly complex ATPase component TadA -
DV445_RS12670 2493206..2494546 - 1341 WP_114922584.1 type IV secretion system protein VirB10 -
DV445_RS12675 2494559..2495407 - 849 WP_114922585.1 TrbG/VirB9 family P-type conjugative transfer protein -
DV445_RS12680 2495404..2496111 - 708 WP_114922586.1 type IV secretion system protein -
DV445_RS13285 2496108..2496263 - 156 WP_205277236.1 hypothetical protein -
DV445_RS13090 2496345..2496509 - 165 WP_162817682.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2470789..2502911 32122


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10092.48 Da        Isoelectric Point: 5.0210

>T108739 WP_114922582.1 NZ_CP031255:c2491742-2491470 [Neisseria elongata]
MQVNWTPEAQSDLDGIVEFIAADNPFAASNLAETLFETAEKLGQMPYIGRTGRVAGTREFVAHPNYILVYKVALDELRIL
RVLHGSRQYP

Download         Length: 273 bp

>T108739 NZ_CP031255:c2491742-2491470 [Neisseria elongata]
ATGCAGGTTAATTGGACACCAGAAGCGCAAAGCGATTTGGACGGCATTGTGGAATTCATTGCCGCCGACAATCCTTTTGC
TGCATCCAACCTTGCCGAAACCCTGTTCGAGACTGCCGAAAAACTCGGGCAGATGCCTTATATCGGCCGTACCGGTAGAG
TGGCGGGCACCCGTGAGTTTGTTGCCCATCCCAACTACATTCTGGTTTACAAAGTGGCTTTGGACGAATTGCGGATTCTG
CGTGTACTGCACGGCAGCAGACAATATCCGTAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7021.89 Da        Isoelectric Point: 4.7185

>AT108739 WP_114922739.1 NZ_CP031255:c2491923-2491732 [Neisseria elongata]
MNTVLKTDPLTYEFASEQEAAEYDAWFRAKVEEALNSGKPPIPHDEVAARIRAKLAEMTKNAG

Download         Length: 192 bp

>AT108739 NZ_CP031255:c2491923-2491732 [Neisseria elongata]
ATGAACACCGTACTGAAAACCGACCCCTTGACCTACGAATTTGCCAGCGAGCAGGAAGCCGCTGAATACGACGCATGGTT
CCGTGCCAAAGTGGAAGAAGCCCTAAACAGCGGCAAACCGCCGATTCCGCACGACGAAGTGGCTGCCCGTATACGTGCCA
AACTGGCGGAGATGACAAAAAATGCAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References