Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2896027..2896591 Replicon chromosome
Accession NZ_CP031229
Organism Ornithinimicrobium sp. AMA3305

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DV701_RS13180 Protein ID WP_114928882.1
Coordinates 2896244..2896591 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DV701_RS13175 Protein ID WP_114928881.1
Coordinates 2896027..2896257 (+) Length 77 a.a.

Genomic Context

DV701_RS13140DV701_RS13150DV701_RS13160DV701_RS13165DV701_RS13175DV701_RS13180DV701_RS13185DV701_RS13195DV701_RS13200DV701_RS13135DV701_RS13145DV701_RS13155DV701_RS13170DV701_RS13190
Location: 2891695..2891997 (303 bp)
Type: Others
Protein ID: WP_114928877.1
Location: 2892477..2892785 (309 bp)
Type: Others
Protein ID: WP_022920209.1
Location: 2893601..2894632 (1032 bp)
Type: Others
Protein ID: WP_114928878.1
Location: 2894930..2895202 (273 bp)
Type: Others
Protein ID: WP_114928879.1
Location: 2896027..2896257 (231 bp)
Type: Antitoxin
Protein ID: WP_114928881.1
Location: 2896244..2896591 (348 bp)
Type: Toxin
Protein ID: WP_114928882.1
Location: 2896866..2898044 (1179 bp)
Type: Others
Protein ID: WP_114928883.1
Location: 2899113..2899376 (264 bp)
Type: Others
Protein ID: WP_114931136.1
Location: 2899376..2899633 (258 bp)
Type: Others
Protein ID: WP_114928885.1
Location: 2891063..2891503 (441 bp)
Type: Others
Protein ID: WP_162803026.1
Location: 2892040..2892324 (285 bp)
Type: Others
Protein ID: WP_022920210.1
Location: 2892997..2893602 (606 bp)
Type: Others
Protein ID: WP_084617068.1
Location: 2895266..2895970 (705 bp)
Type: Others
Protein ID: WP_114928880.1
Location: 2898077..2898646 (570 bp)
Type: Others
Protein ID: WP_114928884.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DV701_RS131352891063..2891503-441WP_162803026.1hypothetical protein-
DV701_RS131402891695..2891997+303WP_114928877.1hypothetical protein-
DV701_RS131452892040..2892324-285WP_022920210.1hypothetical protein-
DV701_RS131502892477..2892785+309WP_022920209.1LysR family transcriptional regulator substrate-binding protein-
DV701_RS131552892997..2893602-606WP_084617068.1Lrp/AsnC family transcriptional regulator-
DV701_RS131602893601..2894632+1032WP_114928878.1pyridoxal-phosphate dependent enzyme-
DV701_RS131652894930..2895202+273WP_114928879.1hypothetical protein-
DV701_RS131702895266..2895970-705WP_114928880.1hypothetical protein-
DV701_RS131752896027..2896257+231WP_114928881.1ribbon-helix-helix domain-containing proteinAntitoxin
DV701_RS131802896244..2896591+348WP_114928882.1type II toxin-antitoxin system PemK/MazF family toxinToxin
DV701_RS131852896866..2898044+1179WP_114928883.1IS110 family transposase-
DV701_RS131902898077..2898646-570WP_114928884.1hypothetical protein-
DV701_RS131952899113..2899376+264WP_114931136.1type II toxin-antitoxin system Phd/YefM family antitoxin-
DV701_RS132002899376..2899633+258WP_114928885.1type II toxin-antitoxin system RelE/ParE family toxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--2889940..291985529915


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-38)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12561.53 Da        Isoelectric Point: 10.6350

>T108640 WP_114928882.1 NZ_CP031229:2896244-2896591 [Ornithinimicrobium sp. AMA3305]
MLRGEILLVDLDPVRGSEANKRRPAVLVSNDRANTMAERLGRGVVTVVPVTSNVERIFPFQVLLPADETGLRVDSKAQAE
QVRSVAVERVGSAVGRVSHRLMAAVDEALRIHLQL

Download         Length: 348 bp

>T108640 NZ_CP031229:2896244-2896591 [Ornithinimicrobium sp. AMA3305]
ATGCTGCGCGGTGAGATCCTTCTCGTCGATCTGGATCCGGTGCGCGGCAGCGAGGCCAACAAGCGGCGGCCCGCGGTGCT
CGTCAGCAATGATCGGGCGAACACCATGGCTGAACGACTCGGTCGTGGAGTAGTCACCGTCGTGCCCGTGACCAGCAACG
TGGAGCGGATCTTCCCGTTCCAGGTGTTGCTGCCAGCCGACGAGACAGGACTGCGGGTGGACTCCAAGGCCCAGGCGGAG
CAGGTGCGCTCCGTCGCAGTCGAGCGGGTCGGTTCTGCGGTAGGCCGGGTGTCGCACCGCCTTATGGCCGCGGTCGACGA
AGCGTTGCGAATCCATCTGCAACTGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8182.90 Da        Isoelectric Point: 3.8705

>AT108640 WP_114928881.1 NZ_CP031229:2896027-2896257 [Ornithinimicrobium sp. AMA3305]
MKVSVSLSEQDLAALDRYVEEAGLESRSAAVQQAIRRLQDPQLEAAYAAAWEEWAVAGDEDAWASTSADGLTDAAR

Download         Length: 231 bp

>AT108640 NZ_CP031229:2896027-2896257 [Ornithinimicrobium sp. AMA3305]
ATGAAGGTGAGTGTGAGTCTGAGCGAGCAAGACCTCGCGGCCCTCGACCGTTACGTGGAAGAAGCTGGCCTCGAGTCGAG
GTCCGCTGCCGTCCAGCAGGCCATCCGCCGTCTGCAAGACCCGCAGCTGGAGGCGGCCTATGCCGCCGCCTGGGAGGAGT
GGGCCGTCGCAGGGGACGAAGACGCGTGGGCGTCAACGTCCGCGGACGGGCTGACCGATGCTGCGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References