Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1714..2183 Replicon plasmid pPla107-1
Accession NZ_CP031227
Organism Pseudomonas amygdali pv. lachrymans str. M301315

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag PLA107_RS39700 Protein ID WP_002556029.1
Coordinates 1714..1995 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag PLA107_RS39705 Protein ID WP_002556028.1
Coordinates 1995..2183 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PLA107_RS39695 153..1295 + 1143 WP_005746165.1 IQ calmodulin-binding motif-containing protein -
PLA107_RS39700 1714..1995 - 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PLA107_RS39705 1995..2183 - 189 WP_002556028.1 hypothetical protein Antitoxin
PLA107_RS39710 2372..3007 - 636 WP_054068142.1 recombinase family protein -
PLA107_RS39715 3322..3954 + 633 WP_003381804.1 ParA family protein -
PLA107_RS39720 3990..4244 + 255 WP_003381801.1 hypothetical protein -
PLA107_RS39725 4669..5334 - 666 WP_004667059.1 LexA family transcriptional regulator -
PLA107_RS39730 5422..5652 + 231 WP_032704469.1 helix-turn-helix domain-containing protein -
PLA107_RS39735 6002..6691 + 690 WP_005746161.1 lytic transglycosylase domain-containing protein -
PLA107_RS39740 6691..7026 + 336 WP_005746160.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..62136 62136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T108634 WP_002556029.1 NZ_CP031227:c1995-1714 [Pseudomonas amygdali pv. lachrymans str. M301315]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T108634 NZ_CP031227:c1995-1714 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACATCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCACCCAAACTACGTCCTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTGATCCACGCCAGACAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT108634 WP_002556028.1 NZ_CP031227:c2183-1995 [Pseudomonas amygdali pv. lachrymans str. M301315]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT108634 NZ_CP031227:c2183-1995 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCACGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References