Detailed information of TA system TA108631

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 1488077..1488590
• Replicon: chromosome
• Accession: NZ_CP031225
• Organism: Pseudomonas amygdali pv. lachrymans str. M301315

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PLA107_RS12280
• Protein ID: WP_004658391.1
• Coordinates: 1488077..1488361 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0N8T2X1
• Locus tag: PLA107_RS12285
• Protein ID: WP_029241049.1
• Coordinates: 1488351..1488590 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PLA107_RS12265	1484220..1486148	+	1929	WP_010198401.1	methyl-accepting chemotaxis protein	-
PLA107_RS12270	1486179..1487111	-	933	WP_039847441.1	DMT family transporter	-
PLA107_RS12275	1487186..1488040	+	855	WP_004658390.1	LysR family transcriptional regulator	-
PLA107_RS12280	1488077..1488361	-	285	WP_004658391.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PLA107_RS12285	1488351..1488590	-	240	WP_029241049.1	CopG family ribbon-helix-helix protein	Antitoxin
PLA107_RS12290	1488750..1489766	-	1017	WP_002552793.1	1-aminocyclopropane-1-carboxylate deaminase	-
PLA107_RS12295	1489953..1490459	+	507	WP_004658394.1	Lrp/AsnC family transcriptional regulator	-
PLA107_RS12300	1490609..1491517	+	909	WP_005744311.1	DUF808 domain-containing protein	-
PLA107_RS12310	1491696..1492481	-	786	WP_002552796.1	membrane protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10647.31 Da
• Isoelectric Point: 10.4249

>T108631 WP_004658391.1 NZ_CP031225:c1488361-1488077 [Pseudomonas amygdali pv. lachrymans str. M301315]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T108631 NZ_CP031225:c1488361-1488077 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGCAGGTTGAGTGGCTTAAAACGGCGCTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACAGGACAATCCAGCTGC
TGCCGCAGCTTTCGTGAAAGCAATTCAATCAAGCGTGACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGGCTACAGGTT
CTAAGGATTTTCCACACCAGAAGACAATCGCCCCCCGTGTGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8715.80 Da
• Isoelectric Point: 4.4354

>AT108631 WP_029241049.1 NZ_CP031225:c1488590-1488351 [Pseudomonas amygdali pv. lachrymans str. M301315]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFANTEDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT108631 NZ_CP031225:c1488590-1488351 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCGGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACTCGCGAGGCATGGCAGATTGCCGAAATTCAGCGCGCGATTG
AAGAAGCCGACGCTGGCGAGTTCGCCAATACAGAGGACGTAAAAGCTGTCATGGACAAATGGTCTGGCAATGCAGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A0N8T2X1