Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 606754..607349 Replicon chromosome
Accession NZ_CP031225
Organism Pseudomonas amygdali pv. lachrymans str. M301315

Toxin (Protein)


Gene name relE Uniprot ID A0A3M3ZKH5
Locus tag PLA107_RS08175 Protein ID WP_005746690.1
Coordinates 607047..607349 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9S822
Locus tag PLA107_RS08170 Protein ID WP_005746689.1
Coordinates 606754..607044 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PLA107_RS08155 604316..605689 - 1374 WP_005746685.1 PepSY domain-containing protein -
PLA107_RS08160 605774..606208 - 435 WP_005746686.1 DUF2946 domain-containing protein -
PLA107_RS08165 606222..606683 - 462 WP_005746687.1 copper chaperone PCu(A)C -
PLA107_RS08170 606754..607044 - 291 WP_005746689.1 putative addiction module antidote protein Antitoxin
PLA107_RS08175 607047..607349 - 303 WP_005746690.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PLA107_RS08180 607499..608239 - 741 WP_005746691.1 cobalt-precorrin-6A reductase -
PLA107_RS08185 608236..609348 - 1113 WP_005746694.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PLA107_RS08190 609348..610550 - 1203 WP_005746695.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
PLA107_RS08195 610676..612016 + 1341 WP_080164792.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-86)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11477.21 Da        Isoelectric Point: 10.6008

>T108630 WP_005746690.1 NZ_CP031225:c607349-607047 [Pseudomonas amygdali pv. lachrymans str. M301315]
MNRFEQTPAFAEWLRSLKDSIGRARILARIRAAELGNFGDCDALGQGVRELRIHHGPGYRVYFARRTGVVYLLLIAGDKS
SQKRDIKFARQLARELCERE

Download         Length: 303 bp

>T108630 NZ_CP031225:c607349-607047 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGAATCGCTTTGAACAGACGCCCGCTTTTGCGGAGTGGTTAAGGTCGTTGAAGGACTCCATTGGCAGAGCTCGAATTCT
GGCTCGAATAAGAGCAGCAGAGCTCGGTAACTTCGGGGACTGCGATGCTTTAGGTCAAGGCGTCAGAGAGCTACGAATAC
ACCATGGACCAGGTTATCGGGTGTATTTTGCCCGACGCACGGGTGTGGTTTACCTGCTCTTGATCGCTGGTGACAAATCG
TCTCAAAAGCGCGACATAAAATTTGCCAGACAGCTGGCGAGAGAGCTCTGTGAGAGGGAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10500.87 Da        Isoelectric Point: 4.5720

>AT108630 WP_005746689.1 NZ_CP031225:c607044-606754 [Pseudomonas amygdali pv. lachrymans str. M301315]
MNNETTPFDTVDYLKTPEDMANYLDACLEEDSGDGLLVRAALNDIARAYGMTQIARDTGLGRESLYKALGANGNPEFTTI
MKVVRAMGIKLHASTR

Download         Length: 291 bp

>AT108630 NZ_CP031225:c607044-606754 [Pseudomonas amygdali pv. lachrymans str. M301315]
ATGAACAACGAGACGACACCGTTCGATACCGTCGACTATTTGAAGACACCTGAAGATATGGCCAATTATCTGGATGCGTG
TCTTGAAGAGGATTCAGGAGACGGGCTGCTCGTAAGGGCCGCGCTGAACGACATAGCAAGGGCTTATGGCATGACACAAA
TCGCACGTGATACAGGTCTTGGTCGTGAGAGCCTCTACAAAGCGCTGGGTGCAAACGGTAATCCAGAGTTCACGACCATC
ATGAAAGTCGTGAGGGCGATGGGGATCAAACTACACGCAAGTACGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M3ZKH5

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9S822

References