Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 3752303..3752957 Replicon chromosome
Accession NZ_CP031223
Organism Psychrobacillus glaciei strain PB01

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PB01_RS17680 Protein ID WP_151701386.1
Coordinates 3752303..3752653 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PB01_RS17685 Protein ID WP_151701387.1
Coordinates 3752658..3752957 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PB01_RS17645 3747807..3748592 - 786 WP_151701379.1 RNA polymerase sigma factor SigB -
PB01_RS17650 3748570..3749040 - 471 WP_151701380.1 anti-sigma B factor RsbW -
PB01_RS17655 3749027..3749371 - 345 WP_151701381.1 anti-sigma factor antagonist -
PB01_RS17660 3749558..3750556 - 999 WP_151701382.1 PP2C family protein-serine/threonine phosphatase -
PB01_RS17665 3750572..3750973 - 402 WP_151701383.1 anti-sigma regulatory factor -
PB01_RS17670 3750980..3751342 - 363 WP_151701384.1 STAS domain-containing protein -
PB01_RS17675 3751339..3752169 - 831 WP_151701385.1 STAS domain-containing protein -
PB01_RS17680 3752303..3752653 - 351 WP_151701386.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PB01_RS17685 3752658..3752957 - 300 WP_151701387.1 transcriptional regulator Antitoxin
PB01_RS17690 3753070..3754176 - 1107 WP_151701388.1 alanine racemase -
PB01_RS17695 3754246..3755265 - 1020 WP_151701389.1 outer membrane lipoprotein carrier protein LolA -
PB01_RS17700 3755324..3755677 - 354 WP_151701390.1 holo-ACP synthase -
PB01_RS17705 3755745..3756365 + 621 WP_151701391.1 rhomboid family intramembrane serine protease -
PB01_RS17710 3756381..3757889 - 1509 WP_151702109.1 PH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12911.90 Da        Isoelectric Point: 5.6262

>T108628 WP_151701386.1 NZ_CP031223:c3752653-3752303 [Psychrobacillus glaciei]
MIVKRGDVFFADLSPVIGSEQGGTRPVLVIQNDIGNRFSPTVIIAAITAQIQKAKLPTHVEINAKQYDFERDSVILLEQL
RTIDKSRLTDKITHLDEDVMQEVDHALGISLGIVKF

Download         Length: 351 bp

>T108628 NZ_CP031223:c3752653-3752303 [Psychrobacillus glaciei]
TTGATCGTAAAACGTGGGGACGTTTTTTTCGCAGATTTATCACCTGTAATCGGGTCTGAGCAAGGGGGAACCAGGCCCGT
TTTGGTGATTCAGAATGATATTGGTAATCGATTTAGTCCTACTGTTATTATTGCAGCTATTACTGCTCAAATACAAAAAG
CAAAGTTGCCAACACATGTTGAAATAAACGCTAAACAGTATGACTTCGAACGCGATTCTGTTATCTTATTAGAACAATTG
CGAACGATAGATAAATCGCGACTAACCGATAAAATTACACACCTTGATGAGGATGTAATGCAAGAAGTAGATCATGCATT
AGGAATTAGTTTAGGAATTGTCAAATTTTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11190.91 Da        Isoelectric Point: 7.8796

>AT108628 WP_151701387.1 NZ_CP031223:c3752957-3752658 [Psychrobacillus glaciei]
MSEVFAVVSDKKKKEAIIRLPKQMVNEGVKTVKQSLTGSESIVRVQANEYFKKEQSNLIREAMMKGYVEMSHINLSICTE
CLHAEYEAQHTTERLVSGG

Download         Length: 300 bp

>AT108628 NZ_CP031223:c3752957-3752658 [Psychrobacillus glaciei]
TTGTCGGAGGTGTTTGCTGTGGTAAGTGATAAGAAGAAAAAGGAAGCTATTATAAGGCTTCCAAAGCAAATGGTTAATGA
AGGAGTAAAGACCGTAAAACAGTCATTAACTGGTAGTGAAAGTATCGTCCGTGTCCAAGCAAATGAATATTTTAAGAAAG
AACAGTCAAATCTTATAAGAGAAGCGATGATGAAAGGCTATGTTGAAATGTCTCATATAAACTTATCCATTTGTACGGAA
TGTTTACATGCAGAGTATGAAGCGCAACATACGACTGAGCGACTCGTAAGTGGAGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References