Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1999180..1999451 Replicon chromosome
Accession NZ_CP031214
Organism Escherichia coli strain C600

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1999310..1999413 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1999180..1999451 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DK885_RS10185 1995735..1996397 - 663 WP_000944256.1 exodeoxyribonuclease X -
DK885_RS10190 1996421..1997077 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DK885_RS10195 1997179..1997409 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DK885_RS10200 1997548..1997922 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DK885_RS10205 1997926..1998798 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
DK885_RS10210 1998811..1999152 + 342 WP_000976476.1 YebY family protein -
- 1999180..1999451 - 272 - - Antitoxin
- 1999310..1999413 + 104 - - Toxin
DK885_RS10215 1999548..2000204 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
DK885_RS10220 2000205..2000396 - 192 WP_000457842.1 YebW family protein -
DK885_RS10225 2000501..2000737 - 237 WP_001295499.1 DUF1480 family protein -
DK885_RS10230 2000855..2002294 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T108575 NZ_CP031214:1999310-1999413 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT108575 NZ_CP031214:c1999451-1999180 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References