Detailed information of TA system TA108555

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pezAT/zeta-ParD
• Location: 3132041..3132981
• Replicon: chromosome
• Accession: NZ_CP031165
• Organism: Euzebya sp. DY32-46

Toxin (Protein)

• Gene name: pezT
• Uniprot ID: -
• Locus tag: DVS28_RS13355
• Protein ID: WP_114591888.1
• Coordinates: 3132041..3132619 (-)
• Length: 193 a.a.

Antitoxin (Protein)

• Gene name: pezA
• Uniprot ID: -
• Locus tag: DVS28_RS13360
• Protein ID: WP_114591889.1
• Coordinates: 3132616..3132981 (-)
• Length: 122 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DVS28_RS13335	3127488..3128456	-	969	WP_114591884.1	alpha/beta hydrolase	-
DVS28_RS13340	3128557..3129327	+	771	WP_114591885.1	type I methionyl aminopeptidase	-
DVS28_RS13345	3129528..3130769	+	1242	WP_114591886.1	ATP-binding protein	-
DVS28_RS13350	3130781..3131884	-	1104	WP_114591887.1	cell wall-binding repeat-containing protein	-
DVS28_RS13355	3132041..3132619	-	579	WP_114591888.1	zeta toxin family protein	Toxin
DVS28_RS13360	3132616..3132981	-	366	WP_114591889.1	hypothetical protein	Antitoxin
DVS28_RS13365	3133432..3134229	-	798	WP_114591890.1	hypothetical protein	-
DVS28_RS13370	3134409..3136004	+	1596	WP_164710491.1	CocE/NonD family hydrolase	-
DVS28_RS13375	3136029..3137267	-	1239	WP_114591892.1	phosphoglycerate mutase	-
DVS28_RS13380	3137338..3137979	-	642	WP_164710492.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (5-132)

Antitoxin

• ParD-like antitoxin of type II bacterial toxin-antitoxin system (4-101)

Sequences

Toxin

Protein

• Length: 193 a.a.
• Molecular weight: 21102.97 Da
• Isoelectric Point: 8.6790

>T108555 WP_114591888.1 NZ_CP031165:c3132619-3132041 [Euzebya sp. DY32-46]
VSRLDLVVGPNGAGKSTFVRFTLAPMRPGVPFVNADVIAAERWPDDQQAHAYEAAAMASRIRETLIARGQPFIAETVFSH
PSKLDLIERADAAGYDIRLHVVMVPPDLSVARVAHRVRAGGHDVPEDKIRQRHDRLWGLVAQAAHRVPIASFYANHRTGP
DLVAVFHHGRPASATEWPTWTHPDLISGLAQN

Nucleotide

• Length: 579 bp

>T108555 NZ_CP031165:c3132619-3132041 [Euzebya sp. DY32-46]
GTGAGTCGGCTCGACTTGGTCGTCGGCCCCAACGGCGCCGGCAAGAGCACGTTCGTGCGCTTCACGCTGGCGCCAATGCG
ACCAGGCGTCCCGTTCGTCAACGCTGACGTCATCGCCGCCGAGCGCTGGCCCGACGACCAGCAGGCCCATGCCTACGAGG
CTGCAGCCATGGCCAGTCGCATCCGCGAGACCCTCATCGCCCGAGGGCAGCCGTTCATCGCCGAGACCGTCTTCTCCCAC
CCCTCCAAGCTTGACCTCATCGAGCGGGCAGACGCGGCCGGCTACGACATCCGCCTCCACGTCGTCATGGTTCCACCGGA
TCTCTCCGTCGCCCGCGTCGCGCACCGCGTCCGCGCCGGCGGTCACGACGTCCCCGAGGACAAGATCCGGCAGCGACACG
ACCGTTTGTGGGGGCTCGTCGCACAGGCGGCACACCGTGTACCCATCGCGTCGTTCTACGCCAACCACCGCACGGGCCCA
GATCTCGTCGCGGTCTTCCACCACGGCAGACCGGCCAGCGCAACGGAATGGCCAACCTGGACCCACCCGGATCTCATCTC
CGGGCTGGCGCAGAACTGA

Antitoxin

Protein

• Length: 122 a.a.
• Molecular weight: 12727.22 Da
• Isoelectric Point: 4.4237

>AT108555 WP_114591889.1 NZ_CP031165:c3132981-3132616 [Euzebya sp. DY32-46]
MGTPVRIDDEVYAAARRVGAVASRSAAQQVDYWVRIGRAVSMAEAGVRNRIDDAIAGRTPLAGLTAEERLLANAEIDAAI
EQAAVSTDYADRLAAEGITTVVMDEAGHLVTRFPDGTSTPA

Nucleotide

• Length: 366 bp

>AT108555 NZ_CP031165:c3132981-3132616 [Euzebya sp. DY32-46]
ATGGGAACGCCGGTCCGCATCGACGACGAGGTCTACGCTGCCGCCCGTAGAGTCGGCGCGGTTGCCAGCCGCTCCGCTGC
GCAGCAGGTCGACTACTGGGTGCGCATCGGTCGTGCCGTCAGCATGGCCGAGGCCGGGGTACGCAACCGCATCGATGACG
CGATCGCCGGCCGGACGCCACTCGCAGGGCTGACTGCGGAGGAACGGCTGCTGGCCAATGCCGAAATCGACGCGGCGATC
GAGCAGGCTGCGGTCTCCACCGACTACGCCGACCGCCTCGCTGCGGAGGGCATCACCACCGTCGTGATGGACGAGGCGGG
CCACCTCGTCACCCGCTTCCCGGACGGCACCTCGACTCCGGCGTGA