Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 649826..650369 Replicon plasmid pDrdI
Accession NZ_CP031163
Organism Deinococcus wulumuqiensis strain NEB 479

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DVJ83_RS18800 Protein ID WP_205413571.1
Coordinates 649826..650071 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DVJ83_RS18805 Protein ID WP_114673751.1
Coordinates 650097..650369 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVJ83_RS18770 644923..646296 + 1374 WP_114673749.1 replication initiator protein A -
DVJ83_RS18775 646603..646761 - 159 Protein_686 IS6 family transposase -
DVJ83_RS18780 646788..647831 - 1044 WP_162865694.1 hypothetical protein -
DVJ83_RS18785 647896..648327 - 432 Protein_688 IS6 family transposase -
DVJ83_RS18790 648329..649312 - 984 WP_114673815.1 IS4 family transposase -
DVJ83_RS18795 649525..649674 - 150 Protein_690 IS6 family transposase -
DVJ83_RS18800 649826..650071 - 246 WP_205413571.1 Txe/YoeB family addiction module toxin Toxin
DVJ83_RS18805 650097..650369 - 273 WP_114673751.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DVJ83_RS19810 650507..651604 - 1098 WP_205413565.1 IS1 family transposase -
DVJ83_RS18815 651731..652906 - 1176 WP_114673816.1 VanW family protein -
DVJ83_RS18820 653022..653501 - 480 WP_114673752.1 fasciclin domain-containing protein -
DVJ83_RS19685 653724..653975 - 252 WP_162865886.1 hypothetical protein -
DVJ83_RS19815 654032..654175 - 144 Protein_697 IS5/IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..668667 668667


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9858.44 Da        Isoelectric Point: 9.8325

>T108554 WP_205413571.1 NZ_CP031163:c650071-649826 [Deinococcus wulumuqiensis]
IFQPEFLEDLTYWVDTDRKTALRLLRMVKEVLKSPFEGIGKPEPLKHLAADTWSRRITQEHRLVYLVRKDRIDFLQARYH
Y

Download         Length: 246 bp

>T108554 NZ_CP031163:c650071-649826 [Deinococcus wulumuqiensis]
ATTTTTCAGCCAGAGTTTCTTGAAGATTTGACCTACTGGGTAGACACTGACCGCAAGACTGCTTTGCGTCTACTCCGGAT
GGTCAAGGAAGTGCTGAAAAGCCCATTTGAGGGCATCGGAAAACCTGAACCACTCAAGCACTTGGCTGCTGATACCTGGT
CACGGCGTATTACGCAAGAACACCGACTGGTTTATCTGGTACGCAAAGACCGAATCGACTTTTTGCAGGCTCGCTACCAC
TACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9942.26 Da        Isoelectric Point: 5.6244

>AT108554 WP_114673751.1 NZ_CP031163:c650369-650097 [Deinococcus wulumuqiensis]
MIERSYTQARAELSELMHRATEDRETVIIERRGHPPVALIAADELSSLQETAHLLRSPVNAQRLLTALNRALAGEGQALS
LSELEQRAGL

Download         Length: 273 bp

>AT108554 NZ_CP031163:c650369-650097 [Deinococcus wulumuqiensis]
ATGATTGAACGAAGCTATACACAGGCCCGCGCTGAACTCTCTGAACTTATGCACCGCGCGACTGAAGACCGAGAAACGGT
CATCATTGAACGTCGTGGGCACCCGCCGGTGGCCTTGATTGCTGCCGACGAGCTCAGCAGCCTGCAAGAAACCGCCCATC
TACTCCGCTCCCCTGTCAATGCCCAGCGCTTGCTAACGGCCCTCAACCGCGCTCTGGCGGGTGAAGGTCAGGCACTCTCT
CTCAGCGAGCTGGAGCAGCGTGCCGGACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References