Detailed information of TA system TA108551

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): chpIK/MazF(toxin)
• Location: 766169..766761
• Replicon: chromosome
• Accession: NZ_CP031158
• Organism: Deinococcus wulumuqiensis strain NEB 479

Toxin (Protein)

• Gene name: chpK
• Uniprot ID: -
• Locus tag: DVJ83_RS03850
• Protein ID: WP_114672733.1
• Coordinates: 766423..766761 (+)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: chpI
• Uniprot ID: -
• Locus tag: DVJ83_RS03845
• Protein ID: WP_114671461.1
• Coordinates: 766169..766414 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DVJ83_RS03830	762211..763425	-	1215	WP_114671458.1	VWA domain-containing protein	-
DVJ83_RS03835	763422..763916	-	495	WP_114671459.1	DUF4274 domain-containing protein	-
DVJ83_RS03840	763913..766132	-	2220	WP_114671460.1	hypothetical protein	-
DVJ83_RS03845	766169..766414	+	246	WP_114671461.1	ChpI protein	Antitoxin
DVJ83_RS03850	766423..766761	+	339	WP_114672733.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
DVJ83_RS03860	766889..768010	-	1122	WP_114671462.1	AAA family ATPase	-
DVJ83_RS03865	768007..768774	-	768	WP_114671463.1	hypothetical protein	-
DVJ83_RS03870	768771..770111	-	1341	WP_114671464.1	hypothetical protein	-
DVJ83_RS03875	770108..771388	-	1281	WP_114671465.1	SWIM zinc finger family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	737928..768774	30846

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (2-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12119.94 Da
• Isoelectric Point: 4.4645

>T108551 WP_114672733.1 NZ_CP031158:766423-766761 [Deinococcus wulumuqiensis]
IERGQIWWADLGEPRGSRPAFARPVIILQIDSINVSQINTVIVVALTSNLNGSDLPGNTVLEPEQSGLQKTSLVNATQIQ
TINKTELLEYVGTLSLLDMRAVDAGLRLVLGL

Nucleotide

• Length: 339 bp

>T108551 NZ_CP031158:766423-766761 [Deinococcus wulumuqiensis]
ATTGAGCGTGGGCAAATCTGGTGGGCCGACCTCGGTGAGCCGCGTGGCAGCCGTCCTGCCTTTGCGCGTCCGGTCATCAT
CTTGCAAATCGATTCCATCAATGTCAGCCAAATCAATACGGTGATTGTGGTGGCCCTGACCAGTAACCTAAACGGCTCGG
ATTTGCCTGGAAATACCGTGCTGGAGCCTGAGCAATCGGGTTTACAGAAGACCAGTCTGGTCAATGCCACTCAGATTCAA
ACCATCAATAAGACAGAATTGTTGGAGTATGTCGGCACTTTAAGCCTCTTGGACATGCGGGCCGTAGATGCGGGTCTGCG
CCTCGTGCTGGGCCTCTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9314.38 Da
• Isoelectric Point: 4.5687

>AT108551 WP_114671461.1 NZ_CP031158:766169-766414 [Deinococcus wulumuqiensis]
MKTAISLTDELFEAVETNAKKLGVSRSQFFAMGAEKLIRQLEAEEITAAYNRVYSAEYGEDPETAEFRKEAARRSFERTE
W

Nucleotide

• Length: 246 bp

>AT108551 NZ_CP031158:766169-766414 [Deinococcus wulumuqiensis]
ATGAAAACGGCTATTTCCTTGACTGATGAGCTTTTTGAAGCGGTAGAAACCAATGCCAAAAAACTGGGCGTGAGCCGGAG
CCAATTTTTTGCGATGGGGGCGGAAAAGCTGATTCGGCAACTTGAGGCCGAGGAAATTACTGCCGCCTACAACCGTGTCT
ATTCGGCGGAATATGGCGAAGACCCGGAGACAGCGGAATTTCGCAAGGAAGCGGCGCGGCGCAGTTTTGAGCGGACAGAG
TGGTGA