Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4445822..4446360 Replicon chromosome
Accession NZ_CP031153
Organism Kordia sp. SMS9

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KORDIASMS9_RS18830 Protein ID WP_114904336.1
Coordinates 4446061..4446360 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KORDIASMS9_RS18825 Protein ID WP_114904335.1
Coordinates 4445822..4446064 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KORDIASMS9_RS18805 4442462..4443400 + 939 WP_114904331.1 IS1595 family transposase -
KORDIASMS9_RS18810 4443791..4444261 - 471 WP_114904332.1 hypothetical protein -
KORDIASMS9_RS18815 4444533..4444973 + 441 WP_162820050.1 hypothetical protein -
KORDIASMS9_RS18820 4444909..4445700 + 792 WP_205318011.1 hypothetical protein -
KORDIASMS9_RS18825 4445822..4446064 + 243 WP_114904335.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
KORDIASMS9_RS18830 4446061..4446360 + 300 WP_114904336.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KORDIASMS9_RS18835 4446499..4448424 + 1926 WP_114904337.1 BatA domain-containing protein -
KORDIASMS9_RS18840 4448421..4449674 + 1254 WP_114904338.1 dihydroorotase -
KORDIASMS9_RS18845 4449674..4450000 + 327 WP_114904339.1 hypothetical protein -
KORDIASMS9_RS18850 4450012..4450665 + 654 WP_114904340.1 dienelactone hydrolase family protein -
KORDIASMS9_RS18855 4450737..4451075 - 339 WP_114904341.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11917.67 Da        Isoelectric Point: 10.1830

>T108549 WP_114904336.1 NZ_CP031153:4446061-4446360 [Kordia sp. SMS9]
MSSSNYRISKEAIKDLNSIWTYTFQKWSKAQADSYYQTIISEFQYISDNFLIGKSVENTRKNYRVLKVKSHLIFYRKIDD
NIVEIVRILHQQMDSKKRL

Download         Length: 300 bp

>T108549 NZ_CP031153:4446061-4446360 [Kordia sp. SMS9]
ATGAGTTCCTCTAATTATCGCATCAGTAAAGAAGCTATTAAAGATTTGAACTCTATTTGGACGTACACCTTTCAAAAATG
GTCTAAAGCGCAAGCAGATTCTTATTATCAAACTATTATTAGTGAATTTCAATATATCTCAGATAATTTCTTGATTGGGA
AATCGGTTGAAAATACTAGAAAAAATTATCGTGTATTAAAAGTTAAATCACACCTCATATTCTATAGAAAAATAGATGAT
AATATTGTTGAGATCGTTAGAATTTTACATCAACAAATGGATAGTAAAAAAAGATTATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9144.29 Da        Isoelectric Point: 5.6588

>AT108549 WP_114904335.1 NZ_CP031153:4445822-4446064 [Kordia sp. SMS9]
MGKNTSISLGNHFEEFINEEVKSGRYTSVSEVIRSALRLLESEEKKERALIKALEIGEQSGFVEDFNPDENLKALHRKHL

Download         Length: 243 bp

>AT108549 NZ_CP031153:4445822-4446064 [Kordia sp. SMS9]
ATGGGGAAAAACACATCTATATCACTAGGAAATCATTTTGAAGAATTTATTAACGAAGAAGTGAAGTCTGGCAGATACAC
TTCTGTGAGTGAAGTGATTCGCTCAGCTTTACGCTTACTTGAAAGTGAAGAAAAAAAAGAACGTGCTTTGATTAAGGCCT
TGGAGATTGGAGAACAAAGTGGATTTGTTGAAGATTTTAATCCTGATGAAAATTTAAAAGCACTGCATCGTAAACACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References