108499

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 3781761..3783117 Replicon chromosome
Accession NZ_CP031123
Organism Providencia huaxiensis strain WCHPr000369

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag CYG50_RS19305 Protein ID WP_102140047.1
Coordinates 3782152..3783117 (+) Length 322 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag CYG50_RS19300 Protein ID WP_102140046.1
Coordinates 3781761..3782165 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG50_RS19290 3777547..3780594 - 3048 WP_102140044.1 formate dehydrogenase-N subunit alpha -
CYG50_RS19295 3780769..3781599 + 831 WP_102140045.1 formate dehydrogenase accessory sulfurtransferase FdhD -
CYG50_RS19300 3781761..3782165 + 405 WP_102140046.1 S-adenosylhomocysteine hydrolase Antitoxin
CYG50_RS19305 3782152..3783117 + 966 WP_102140047.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CYG50_RS19310 3783189..3784553 - 1365 WP_102140048.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
CYG50_RS19315 3784655..3786304 - 1650 WP_004906225.1 membrane protein insertase YidC -
CYG50_RS19320 3786307..3786567 - 261 WP_102140049.1 membrane protein insertion efficiency factor YidD -
CYG50_RS19325 3786531..3786890 - 360 WP_102140050.1 ribonuclease P protein component -
CYG50_RS19330 3786912..3787055 - 144 WP_042846776.1 50S ribosomal protein L34 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-300)

Antitoxin

Protein of unknown function DUF6088

(6-131)


Sequences

Toxin        


Download         Length: 322 a.a.        Molecular weight: 37124.16 Da        Isoelectric Point: 5.0044

>T108499 WP_102140047.1 NZ_CP031123:3782152-3783117 [Providencia huaxiensis]
MKLDSSLFIDVADAIGLGNPAIVEKDYYVVQLLKLLSNFQFTYHQAIFSGGTALAKSDIKTYRMSEDIDIKLIPNQRYSE
LASRNARKTARREIKNIIEEIINQNSIFSLDNAPSVKDEYRYFSFDIRYPQDHRQAPCLRPFIKLEFIETDLLSEPISRN
IQSIYSNVTESDIEIYNMICSAIIDTQAEKLLSMLRRTASVARNGQREDDETLIRHVYDTFHIQLSQPSNIEFLSQLLKK
ALDGDITRYGNQHTQLVDSPITELRYGLKLLVETPKFIERYNNYVSPMVYAEVPTQWDEAIIAFTSLAHQVLDYIEQELN
K

Download         Length: 966 bp

>T108499 NZ_CP031123:3782152-3783117 [Providencia huaxiensis]
ATGAAACTCGATAGCTCTTTATTTATTGATGTTGCCGATGCCATAGGGCTCGGCAACCCAGCGATAGTTGAAAAAGATTA
TTATGTTGTTCAATTACTTAAACTCCTATCTAACTTTCAGTTTACATATCACCAAGCTATCTTTTCAGGAGGAACAGCTC
TCGCCAAATCGGATATCAAAACTTATCGAATGTCTGAAGACATTGATATAAAACTAATTCCAAACCAAAGATATTCTGAA
TTAGCATCTCGAAATGCAAGAAAAACAGCCCGAAGAGAAATAAAAAACATTATTGAAGAAATAATTAACCAAAATTCTAT
TTTTTCTTTAGATAATGCGCCTTCTGTTAAAGATGAATACCGCTATTTTTCCTTTGATATCCGTTATCCTCAAGATCACA
GGCAAGCACCATGTTTACGTCCTTTTATAAAATTAGAATTTATAGAGACAGACCTTCTTAGTGAACCCATATCTAGGAAT
ATTCAATCTATTTATTCAAATGTTACAGAATCTGATATCGAAATTTATAACATGATTTGCTCGGCAATTATTGACACTCA
AGCTGAAAAGTTACTATCGATGCTACGAAGAACAGCGAGTGTCGCAAGAAATGGCCAACGTGAAGATGATGAGACACTTA
TTCGACATGTTTATGATACTTTTCATATACAGCTATCCCAACCATCTAATATTGAATTCTTAAGTCAATTACTGAAAAAA
GCACTTGATGGAGATATTACAAGATATGGAAATCAACATACACAACTGGTTGACTCGCCTATTACAGAACTTCGCTATGG
GCTAAAATTATTAGTAGAAACCCCAAAATTCATAGAGCGTTATAATAACTATGTAAGTCCTATGGTTTATGCAGAAGTTC
CTACTCAATGGGATGAAGCAATTATTGCTTTTACTAGCTTAGCTCATCAAGTATTGGATTATATAGAACAAGAACTTAAT
AAATAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15286.99 Da        Isoelectric Point: 11.0636

>AT108499 WP_102140046.1 NZ_CP031123:3781761-3782165 [Providencia huaxiensis]
MTIQDRIQKKVKRSKRSVFLRSDFSKIADYDQVGRILKKLTDNGLLMRIGYGVYVRARVNRITGKLMPDNPSGADGVIIE
VMKKLNVDYTFDKLSLMNLSGESTQIPSNIKIIPKNPKFTRKIKVGKQSINETR

Download         Length: 405 bp

>AT108499 NZ_CP031123:3781761-3782165 [Providencia huaxiensis]
ATGACAATACAAGACAGAATACAAAAAAAAGTAAAGCGTTCTAAACGTTCTGTTTTCCTACGCTCTGACTTTTCAAAAAT
AGCTGATTATGATCAAGTAGGCCGTATACTCAAAAAACTTACAGACAATGGTTTATTAATGAGAATTGGTTATGGTGTCT
ATGTAAGAGCCAGAGTGAATCGCATCACTGGTAAATTAATGCCAGATAACCCAAGTGGTGCTGATGGCGTTATTATCGAA
GTAATGAAAAAACTCAATGTTGATTATACTTTTGATAAGCTATCTCTGATGAATTTGTCTGGTGAGAGTACACAAATTCC
TTCTAATATTAAAATCATCCCTAAAAATCCTAAATTTACTCGTAAAATTAAGGTAGGGAAACAAAGTATCAATGAAACTC
GATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References