Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3228905..3229701 Replicon chromosome
Accession NZ_CP031123
Organism Providencia huaxiensis strain WCHPr000369

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CYG50_RS16565 Protein ID WP_102138079.1
Coordinates 3228905..3229417 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CYG50_RS16570 Protein ID WP_102138080.1
Coordinates 3229414..3229701 (-) Length 96 a.a.

Genomic Context

CYG50_RS16555CYG50_RS16560CYG50_RS16550CYG50_RS16565CYG50_RS16570CYG50_RS16575CYG50_RS16580CYG50_RS16585CYG50_RS16590
Location: 3226145..3227482 (1338 bp)
Type: Others
Protein ID: WP_102138077.1
Location: 3227495..3228829 (1335 bp)
Type: Others
Protein ID: WP_102138078.1
Location: 3224957..3225928 (972 bp)
Type: Others
Protein ID: WP_102138076.1
Location: 3228905..3229417 (513 bp)
Type: Toxin
Protein ID: WP_102138079.1
Location: 3229414..3229701 (288 bp)
Type: Antitoxin
Protein ID: WP_102138080.1
Location: 3229950..3231005 (1056 bp)
Type: Others
Protein ID: WP_102138081.1
Location: 3231010..3231780 (771 bp)
Type: Others
Protein ID: WP_102138082.1
Location: 3231811..3232614 (804 bp)
Type: Others
Protein ID: WP_102138083.1
Location: 3232614..3234428 (1815 bp)
Type: Others
Protein ID: WP_102138084.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CYG50_RS165503224957..3225928-972WP_102138076.1DNA-binding transcriptional regulator DsdC-
CYG50_RS165553226145..3227482+1338WP_102138077.1D-serine transporter DsdX-
CYG50_RS165603227495..3228829+1335WP_102138078.1D-serine ammonia-lyase-
CYG50_RS165653228905..3229417-513WP_102138079.1GNAT family N-acetyltransferaseToxin
CYG50_RS165703229414..3229701-288WP_102138080.1DUF1778 domain-containing proteinAntitoxin
CYG50_RS165753229950..3231005-1056WP_102138081.1osmoprotectant NAGGN system M42 family peptidase-
CYG50_RS165803231010..3231780-771WP_102138082.1FadR family transcriptional regulator-
CYG50_RS165853231811..3232614-804WP_102138083.1ABC transporter ATP-binding protein-
CYG50_RS165903232614..3234428-1815WP_102138084.1dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(35-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18369.25 Da        Isoelectric Point: 9.8443

>T108495 WP_102138079.1 NZ_CP031123:c3229417-3228905 [Providencia huaxiensis]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKNRAMSYQNSGASRTFVTTSDNQVMGYYALSTGVVSTNQAAGRFRRNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGVVVHALTDNAKRFYEHIGFVPSPLDSMMLMITLAD
LQFALGIHPN

Download         Length: 513 bp

>T108495 NZ_CP031123:c3229417-3228905 [Providencia huaxiensis]
ATGACATTGAAGCTAACAGCGCCAGAACCACTAAAAACAGGCCATTTACTGGAAGGGTTTTCCTCTGGTGAAGAGGCATT
GGATCTCTGGTTAAAAAACCGGGCAATGAGTTATCAAAACTCAGGGGCCTCGCGCACTTTTGTGACCACTTCGGATAACC
AAGTAATGGGTTACTATGCCTTGTCCACCGGGGTTGTGAGCACCAATCAAGCCGCTGGGCGATTTCGCCGCAACATGCCC
TCTGACATTCCCGTCATCTTACTCGGCAGGCTAGCTGTAGATACAAGGGCGAAGGGTCTTGGAGTTGGTAGGGGGTTAGT
TAAAGATGCCTGTCATCGTGTTATTCAGGCTTCTGGGCTGGTGGGCATTCGAGGGGTTGTGGTTCACGCATTAACGGACA
ATGCTAAACGGTTCTATGAGCACATTGGTTTCGTCCCTTCACCACTTGACTCTATGATGTTGATGATAACGCTTGCCGAT
CTACAATTCGCATTGGGTATTCACCCGAACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10607.97 Da        Isoelectric Point: 4.8660

>AT108495 WP_102138080.1 NZ_CP031123:c3229701-3229414 [Providencia huaxiensis]
MSTQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSAEVYQEFISQLDAAPSSN
EALRKTMMSKSPWEE

Download         Length: 288 bp

>AT108495 NZ_CP031123:c3229701-3229414 [Providencia huaxiensis]
ATGTCGACTCAAAATGATGTTGCCGTGACTCGCTCATCTCTTAACCTGAGAATAAAACCGGAAGACAAAATCCTGATCGA
CCGTGCTGCGAATGCTGTGGGAAAAAACCGTACCGAATTTGTTCTGGAAGCAGCGCGGCGTGCAGCTGAAGAAACACTGG
CCGATCTGCGGGTGATTAACGTCAGCGCCGAGGTTTACCAAGAATTTATCAGCCAGCTTGATGCCGCGCCGAGTAGTAAT
GAGGCATTGAGGAAAACGATGATGTCTAAATCCCCTTGGGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References