Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3228905..3229701 Replicon chromosome
Accession NZ_CP031123
Organism Providencia huaxiensis strain WCHPr000369

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CYG50_RS16565 Protein ID WP_102138079.1
Coordinates 3228905..3229417 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CYG50_RS16570 Protein ID WP_102138080.1
Coordinates 3229414..3229701 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG50_RS16550 3224957..3225928 - 972 WP_102138076.1 DNA-binding transcriptional regulator DsdC -
CYG50_RS16555 3226145..3227482 + 1338 WP_102138077.1 D-serine transporter DsdX -
CYG50_RS16560 3227495..3228829 + 1335 WP_102138078.1 D-serine ammonia-lyase -
CYG50_RS16565 3228905..3229417 - 513 WP_102138079.1 GNAT family N-acetyltransferase Toxin
CYG50_RS16570 3229414..3229701 - 288 WP_102138080.1 DUF1778 domain-containing protein Antitoxin
CYG50_RS16575 3229950..3231005 - 1056 WP_102138081.1 osmoprotectant NAGGN system M42 family peptidase -
CYG50_RS16580 3231010..3231780 - 771 WP_102138082.1 FadR family transcriptional regulator -
CYG50_RS16585 3231811..3232614 - 804 WP_102138083.1 ABC transporter ATP-binding protein -
CYG50_RS16590 3232614..3234428 - 1815 WP_102138084.1 dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(35-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18369.25 Da        Isoelectric Point: 9.8443

>T108495 WP_102138079.1 NZ_CP031123:c3229417-3228905 [Providencia huaxiensis]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKNRAMSYQNSGASRTFVTTSDNQVMGYYALSTGVVSTNQAAGRFRRNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGVVVHALTDNAKRFYEHIGFVPSPLDSMMLMITLAD
LQFALGIHPN

Download         Length: 513 bp

>T108495 NZ_CP031123:c3229417-3228905 [Providencia huaxiensis]
ATGACATTGAAGCTAACAGCGCCAGAACCACTAAAAACAGGCCATTTACTGGAAGGGTTTTCCTCTGGTGAAGAGGCATT
GGATCTCTGGTTAAAAAACCGGGCAATGAGTTATCAAAACTCAGGGGCCTCGCGCACTTTTGTGACCACTTCGGATAACC
AAGTAATGGGTTACTATGCCTTGTCCACCGGGGTTGTGAGCACCAATCAAGCCGCTGGGCGATTTCGCCGCAACATGCCC
TCTGACATTCCCGTCATCTTACTCGGCAGGCTAGCTGTAGATACAAGGGCGAAGGGTCTTGGAGTTGGTAGGGGGTTAGT
TAAAGATGCCTGTCATCGTGTTATTCAGGCTTCTGGGCTGGTGGGCATTCGAGGGGTTGTGGTTCACGCATTAACGGACA
ATGCTAAACGGTTCTATGAGCACATTGGTTTCGTCCCTTCACCACTTGACTCTATGATGTTGATGATAACGCTTGCCGAT
CTACAATTCGCATTGGGTATTCACCCGAACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10607.97 Da        Isoelectric Point: 4.8660

>AT108495 WP_102138080.1 NZ_CP031123:c3229701-3229414 [Providencia huaxiensis]
MSTQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSAEVYQEFISQLDAAPSSN
EALRKTMMSKSPWEE

Download         Length: 288 bp

>AT108495 NZ_CP031123:c3229701-3229414 [Providencia huaxiensis]
ATGTCGACTCAAAATGATGTTGCCGTGACTCGCTCATCTCTTAACCTGAGAATAAAACCGGAAGACAAAATCCTGATCGA
CCGTGCTGCGAATGCTGTGGGAAAAAACCGTACCGAATTTGTTCTGGAAGCAGCGCGGCGTGCAGCTGAAGAAACACTGG
CCGATCTGCGGGTGATTAACGTCAGCGCCGAGGTTTACCAAGAATTTATCAGCCAGCTTGATGCCGCGCCGAGTAGTAAT
GAGGCATTGAGGAAAACGATGATGTCTAAATCCCCTTGGGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References