Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2391381..2392038 Replicon chromosome
Accession NZ_CP031123
Organism Providencia huaxiensis strain WCHPr000369

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CYG50_RS12720 Protein ID WP_102137433.1
Coordinates 2391381..2391791 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4C097
Locus tag CYG50_RS12725 Protein ID WP_004261864.1
Coordinates 2391772..2392038 (-) Length 89 a.a.

Genomic Context

CYG50_RS12715CYG50_RS12730CYG50_RS12735CYG50_RS12740CYG50_RS12700CYG50_RS12705CYG50_RS12710CYG50_RS12720CYG50_RS12725
Location: 2390752..2391270 (519 bp)
Type: Others
Protein ID: WP_102137434.1
Location: 2392286..2393269 (984 bp)
Type: Others
Protein ID: WP_102137432.1
Location: 2393281..2393901 (621 bp)
Type: Others
Protein ID: WP_102137431.1
Location: 2394142..2395038 (897 bp)
Type: Others
Protein ID: WP_168222855.1
Location: 2387263..2388996 (1734 bp)
Type: Others
Protein ID: WP_102137436.1
Location: 2389006..2389710 (705 bp)
Type: Others
Protein ID: WP_102137788.1
Location: 2389732..2390634 (903 bp)
Type: Others
Protein ID: WP_102137435.1
Location: 2391381..2391791 (411 bp)
Type: Toxin
Protein ID: WP_102137433.1
Location: 2391772..2392038 (267 bp)
Type: Antitoxin
Protein ID: WP_004261864.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CYG50_RS127002387263..2388996-1734WP_102137436.1single-stranded-DNA-specific exonuclease RecJ-
CYG50_RS127052389006..2389710-705WP_102137788.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
CYG50_RS127102389732..2390634-903WP_102137435.1site-specific tyrosine recombinase XerD-
CYG50_RS127152390752..2391270+519WP_102137434.1flavodoxin FldB-
CYG50_RS127202391381..2391791-411WP_102137433.1protein YgfXToxin
CYG50_RS127252391772..2392038-267WP_004261864.1FAD assembly factor SdhEAntitoxin
CYG50_RS127302392286..2393269+984WP_102137432.1tRNA-modifying protein YgfZ-
CYG50_RS127352393281..2393901+621WP_102137431.1HD domain-containing protein-
CYG50_RS127402394142..2395038+897WP_168222855.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15570.46 Da        Isoelectric Point: 10.6521

>T108494 WP_102137433.1 NZ_CP031123:c2391791-2391381 [Providencia huaxiensis]
VVLWKSNLSISWKTQLFSTCVHGVVGMFLLLAPWSPDNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWRILKAPWLSRYGVLLTLEALQGKPQKVHLWIAKDAVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T108494 NZ_CP031123:c2391791-2391381 [Providencia huaxiensis]
GTGGTCCTGTGGAAATCTAATCTCTCCATTTCATGGAAAACTCAATTGTTCTCAACCTGTGTTCATGGGGTTGTTGGGAT
GTTTTTACTATTGGCTCCATGGTCCCCTGATAACTCAATGATATGGTTGCCGCTATTAGTGGTTGTCGTTGCGAGTTGGG
CAAAGAGCCAGAAAAATATCAGTAAAATAAAAGGGGTTGCTGTACTGGTTAATGGCAATAAGGTTCAATGGAAGAAAAAT
GAGTGGAGAATACTGAAAGCGCCTTGGCTTAGCCGTTATGGGGTATTGCTGACACTAGAAGCTTTGCAAGGTAAACCGCA
AAAGGTTCATTTATGGATAGCGAAAGATGCTGTGTCAGAAGAGAATTGGCGTAATTTAAACCAGTTATTACTGCAATACC
CTGATATCTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10684.24 Da        Isoelectric Point: 4.8942

>AT108494 WP_004261864.1 NZ_CP031123:c2392038-2391772 [Providencia huaxiensis]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDDLTTHDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp

>AT108494 NZ_CP031123:c2392038-2391772 [Providencia huaxiensis]
ATGGATATTGAGAATAAAGCGCGAATTCATTGGGCATGCCGTCGTGGTATGCGTGAATTAGATATTTCAATCATGCCGTT
TTTTGAGTATGAATATGATGACCTAACAACTCACGATAAGCAGGTATTTGTCCGTTTATTAGAATGTGCGGACCCTGATT
TATTCAATTGGTTAATGAATCATGGTCGCCCAGATGATGACGAACTTTTTCGTATGATTAAACTGATTCAGGAAAAAAAT
AAAAATCGTGGTCCTGTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A345M2Q5

References