Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4615157..4615817 Replicon chromosome
Accession NZ_CP031104
Organism Leclercia sp. W6

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DVA43_RS22770 Protein ID WP_103822769.1
Coordinates 4615404..4615817 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag DVA43_RS22765 Protein ID WP_103176875.1
Coordinates 4615157..4615423 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVA43_RS22740 4610315..4611748 - 1434 WP_114316854.1 6-phospho-beta-glucosidase -
DVA43_RS22745 4611863..4612594 - 732 WP_114316855.1 MurR/RpiR family transcriptional regulator -
DVA43_RS22750 4612647..4612958 + 312 WP_114316856.1 N(4)-acetylcytidine aminohydrolase -
DVA43_RS22755 4613124..4613783 + 660 WP_114316857.1 hemolysin III family protein -
DVA43_RS22760 4613874..4614854 - 981 WP_114316858.1 tRNA-modifying protein YgfZ -
DVA43_RS22765 4615157..4615423 + 267 WP_103176875.1 FAD assembly factor SdhE Antitoxin
DVA43_RS22770 4615404..4615817 + 414 WP_103822769.1 protein YgfX Toxin
DVA43_RS22775 4615822..4616343 - 522 WP_103176873.1 flavodoxin FldB -
DVA43_RS22780 4616444..4617340 + 897 WP_103822768.1 site-specific tyrosine recombinase XerD -
DVA43_RS22785 4617362..4618075 + 714 WP_114316859.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DVA43_RS22790 4618081..4619814 + 1734 WP_114316860.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16236.11 Da        Isoelectric Point: 10.9455

>T108432 WP_103822769.1 NZ_CP031104:4615404-4615817 [Leclercia sp. W6]
VVLWQSDLRVSWRAQWMSLLLHGLVAAVILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWQDS
EWEIVGTPWMLKSGMMLRLRKGAGQRCHHLWLAADSMDEAEWRDLRRMMSHQPTQGR

Download         Length: 414 bp

>T108432 NZ_CP031104:4615404-4615817 [Leclercia sp. W6]
GTGGTCCTGTGGCAATCTGATCTACGCGTCTCATGGCGCGCCCAGTGGATGTCGCTTCTGCTCCACGGCCTGGTCGCGGC
TGTTATTCTTTTGATGCCGTGGCCGCTGAGCTACACCCCATTATGGCTGATGCTACTGTCGCTGGTGGTGTTTGATAGCG
TACGCAGTCAGCGGCGCATTAACGCCCGTCAGGGTGAAATCAAACTGTTTATGGATTCCCGTCTGCACTGGCAAGACAGC
GAGTGGGAAATTGTCGGCACGCCGTGGATGCTGAAATCCGGCATGATGCTCCGCTTACGCAAAGGCGCGGGTCAGCGCTG
CCATCATTTATGGCTGGCGGCAGACAGTATGGATGAAGCGGAGTGGCGGGATCTGCGTCGGATGATGTCGCACCAGCCGA
CGCAGGGGCGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.97 Da        Isoelectric Point: 4.8382

>AT108432 WP_103176875.1 NZ_CP031104:4615157-4615423 [Leclercia sp. W6]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKHLFVRLLENDDPDLFNWLMNHGKPADAELQRMVLLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT108432 NZ_CP031104:4615157-4615423 [Leclercia sp. W6]
ATGGACATTAATAACAAAGCCCGCATTCACTGGGCATGCCGTCGCGGCATGCGCGAACTCGATATCTCCATCATGCCGTT
CTTCGAATATGAATATGACAGCCTGAGCGATGAGGATAAGCATCTCTTCGTCCGCCTGCTGGAGAACGACGATCCCGATT
TATTTAACTGGTTGATGAATCACGGCAAACCTGCCGACGCCGAGCTGCAACGGATGGTGCTTTTAATTCAGACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References