Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3043132..3043696 Replicon chromosome
Accession NZ_CP031104
Organism Leclercia sp. W6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DVA43_RS14865 Protein ID WP_114315981.1
Coordinates 3043132..3043437 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DVA43_RS14870 Protein ID WP_114315982.1
Coordinates 3043424..3043696 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVA43_RS14845 3038566..3039453 + 888 WP_114315978.1 WYL domain-containing protein -
DVA43_RS14850 3039671..3041824 + 2154 WP_114315979.1 carbon starvation protein A -
DVA43_RS14855 3041891..3042094 + 204 WP_032616354.1 YbdD/YjiX family protein -
DVA43_RS14860 3042105..3043058 + 954 WP_114315980.1 GTPase -
DVA43_RS14865 3043132..3043437 - 306 WP_114315981.1 type II toxin-antitoxin system YafQ family toxin Toxin
DVA43_RS14870 3043424..3043696 - 273 WP_114315982.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DVA43_RS14875 3044124..3044669 + 546 WP_114315983.1 porin -
DVA43_RS14880 3044769..3046139 - 1371 WP_114315984.1 NAD-dependent succinate-semialdehyde dehydrogenase -
DVA43_RS14890 3046707..3046838 - 132 Protein_2865 toxin-antitoxin system, antitoxin component -
DVA43_RS14895 3046889..3047311 - 423 WP_114315986.1 hypothetical protein -
DVA43_RS14900 3047289..3047681 - 393 WP_103178111.1 Rhs-Related protein -
DVA43_RS14905 3047865..3048608 + 744 WP_114315987.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(13-101)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-69)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11530.14 Da        Isoelectric Point: 7.4643

>T108427 WP_114315981.1 NZ_CP031104:c3043437-3043132 [Leclercia sp. W6]
MGKSKRAPLPFRSDYTKTFVKAWERYNKAGRRDMHDTAAIMSLVLSGNPIPAEYSDHALTGDMQGFRELHIGGDYLLIYR
VDDKKHLVVFTDLGTHAELFE

Download         Length: 306 bp

>T108427 NZ_CP031104:c3043437-3043132 [Leclercia sp. W6]
ATGGGAAAGAGTAAACGCGCCCCGCTACCATTCCGATCTGATTACACCAAAACCTTTGTTAAGGCATGGGAACGCTACAA
CAAAGCAGGCCGGAGAGATATGCACGATACAGCAGCGATCATGTCGTTAGTGCTTTCCGGCAATCCCATTCCCGCCGAAT
ACAGCGACCACGCCCTGACTGGTGATATGCAAGGATTTCGGGAACTGCATATTGGGGGTGATTATCTTCTCATTTATCGC
GTCGATGATAAAAAGCATTTGGTGGTGTTTACCGACCTGGGGACACATGCGGAGCTGTTTGAGTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10206.54 Da        Isoelectric Point: 5.8874

>AT108427 WP_114315982.1 NZ_CP031104:c3043696-3043424 [Leclercia sp. W6]
MDSVIRSRIDSELKARAGDVLESCGLNWSTAIRLFAEQIVKNEGIPFEVTRKPTTRLRNAMREAEEISTHQNGRFDGVEQ
LMESLKNGKE

Download         Length: 273 bp

>AT108427 NZ_CP031104:c3043696-3043424 [Leclercia sp. W6]
ATGGATTCCGTTATTCGATCACGTATTGACAGTGAACTAAAAGCTCGCGCGGGCGATGTGCTTGAAAGCTGTGGCCTTAA
CTGGAGCACGGCGATACGCCTGTTTGCAGAACAGATTGTTAAAAATGAAGGGATTCCTTTTGAGGTAACCCGCAAACCTA
CTACACGGTTACGCAATGCGATGCGCGAAGCCGAAGAGATTTCCACACACCAGAATGGACGCTTCGATGGTGTTGAACAG
CTCATGGAGAGCTTAAAAAATGGGAAAGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References