Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 841990..842650 Replicon chromosome
Accession NZ_CP031101
Organism Leclercia sp. W17

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DVA44_RS04235 Protein ID WP_103822769.1
Coordinates 842237..842650 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag DVA44_RS04230 Protein ID WP_103176875.1
Coordinates 841990..842256 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVA44_RS04200 837153..838586 - 1434 WP_114385802.1 6-phospho-beta-glucosidase -
DVA44_RS04205 838701..839432 - 732 WP_114385803.1 MurR/RpiR family transcriptional regulator -
DVA44_RS04210 839485..839796 + 312 WP_114316856.1 N(4)-acetylcytidine aminohydrolase -
DVA44_RS04215 839962..840621 + 660 WP_114316857.1 hemolysin III family protein -
DVA44_RS04225 840707..841687 - 981 WP_114385804.1 tRNA-modifying protein YgfZ -
DVA44_RS04230 841990..842256 + 267 WP_103176875.1 FAD assembly factor SdhE Antitoxin
DVA44_RS04235 842237..842650 + 414 WP_103822769.1 protein YgfX Toxin
DVA44_RS04240 842655..843176 - 522 WP_103176873.1 flavodoxin FldB -
DVA44_RS04245 843277..844173 + 897 WP_103822768.1 site-specific tyrosine recombinase XerD -
DVA44_RS04250 844195..844908 + 714 WP_114316859.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DVA44_RS04255 844914..846647 + 1734 WP_114385805.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16236.11 Da        Isoelectric Point: 10.9455

>T108400 WP_103822769.1 NZ_CP031101:842237-842650 [Leclercia sp. W17]
VVLWQSDLRVSWRAQWMSLLLHGLVAAVILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWQDS
EWEIVGTPWMLKSGMMLRLRKGAGQRCHHLWLAADSMDEAEWRDLRRMMSHQPTQGR

Download         Length: 414 bp

>T108400 NZ_CP031101:842237-842650 [Leclercia sp. W17]
GTGGTCCTGTGGCAATCTGATCTACGCGTCTCATGGCGCGCCCAGTGGATGTCGCTTCTGCTCCACGGCCTGGTCGCGGC
TGTTATTCTTTTGATGCCGTGGCCGCTGAGCTACACCCCATTATGGCTGATGCTACTGTCGCTGGTGGTGTTTGATAGCG
TACGCAGTCAGCGGCGCATTAACGCCCGTCAGGGTGAAATCAAACTGTTTATGGATTCCCGTCTGCACTGGCAAGACAGC
GAGTGGGAAATTGTCGGCACGCCGTGGATGCTGAAATCCGGCATGATGCTCCGCTTACGCAAAGGCGCGGGTCAGCGCTG
CCATCATTTATGGCTGGCGGCAGACAGTATGGATGAAGCGGAGTGGCGGGATCTGCGTCGGATGATGTCGCACCAGCCGA
CGCAGGGGCGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.97 Da        Isoelectric Point: 4.8382

>AT108400 WP_103176875.1 NZ_CP031101:841990-842256 [Leclercia sp. W17]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKHLFVRLLENDDPDLFNWLMNHGKPADAELQRMVLLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT108400 NZ_CP031101:841990-842256 [Leclercia sp. W17]
ATGGACATTAATAACAAAGCCCGCATTCACTGGGCATGCCGTCGCGGCATGCGCGAACTCGATATCTCCATCATGCCGTT
CTTCGAATATGAATATGACAGCCTGAGCGATGAGGATAAGCATCTCTTCGTCCGCCTGCTGGAGAACGACGATCCCGATT
TATTTAACTGGTTGATGAATCACGGCAAACCTGCCGACGCCGAGCTGCAACGGATGGTGCTTTTAATTCAGACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References