Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 468513..469015 Replicon chromosome
Accession NZ_CP031093
Organism Hydrocarboniclastica marina strain soil36-7

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag soil367_RS02095 Protein ID WP_136546453.1
Coordinates 468513..468767 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag soil367_RS02100 Protein ID WP_136546455.1
Coordinates 468764..469015 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
soil367_RS02050 464379..464780 - 402 WP_136546439.1 PIN domain nuclease -
soil367_RS02055 464777..464971 - 195 WP_061334038.1 type II toxin-antitoxin system VapB family antitoxin -
soil367_RS02060 465122..465436 + 315 WP_136546441.1 carboxymuconolactone decarboxylase family protein -
soil367_RS02065 465678..466352 + 675 WP_136546443.1 hypothetical protein -
soil367_RS02070 466438..466662 + 225 WP_136546445.1 addiction module protein -
soil367_RS02075 466659..466952 + 294 WP_136546447.1 type II toxin-antitoxin system RelE/ParE family toxin -
soil367_RS02080 467036..467332 - 297 Protein_412 CcdB family protein -
soil367_RS02085 467332..467577 - 246 WP_136546449.1 type II toxin-antitoxin system CcdA family antitoxin -
soil367_RS02090 467761..468501 + 741 WP_136546451.1 sulfite exporter TauE/SafE family protein -
soil367_RS02095 468513..468767 - 255 WP_136546453.1 Txe/YoeB family addiction module toxin Toxin
soil367_RS02100 468764..469015 - 252 WP_136546455.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
soil367_RS02105 469044..469559 + 516 WP_136546457.1 hypothetical protein -
soil367_RS02110 469704..469922 - 219 WP_136550477.1 DUF2798 domain-containing protein -
soil367_RS02115 469987..470478 - 492 WP_136546459.1 DUF2938 domain-containing protein -
soil367_RS02120 470558..471016 + 459 WP_136546461.1 helix-turn-helix domain-containing protein -
soil367_RS02125 471030..471156 - 127 Protein_421 Txe/YoeB family addiction module toxin -
soil367_RS02130 471242..471601 + 360 WP_136546463.1 VOC family protein -
soil367_RS02135 471683..472000 + 318 WP_136546465.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 460003..469559 9556


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10165.72 Da        Isoelectric Point: 9.8161

>T108396 WP_136546453.1 NZ_CP031093:c468767-468513 [Hydrocarboniclastica marina]
VKLIFSEHAWEDYLYWQKTDKKLVNRINKLIKETKREPFEGVGKPEPLKHSLAGYWARRINDEQRIVYKVTDDALLIAQL
RYQY

Download         Length: 255 bp

>T108396 NZ_CP031093:c468767-468513 [Hydrocarboniclastica marina]
GTGAAACTCATCTTCTCTGAGCATGCCTGGGAGGACTATCTGTACTGGCAGAAAACCGACAAAAAGCTTGTTAATCGAAT
CAACAAGCTGATCAAAGAGACCAAGCGCGAACCGTTCGAAGGTGTTGGCAAACCCGAGCCCCTCAAACACAGCCTCGCCG
GGTACTGGGCTCGCCGGATCAACGACGAACAGCGAATAGTTTACAAAGTCACGGATGACGCGTTGCTTATCGCCCAGCTC
CGGTATCAGTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9222.48 Da        Isoelectric Point: 4.4750

>AT108396 WP_136546455.1 NZ_CP031093:c469015-468764 [Hydrocarboniclastica marina]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKSPSVVMISLEDYEALQETAYLLRAPKNARRLLEAVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT108396 NZ_CP031093:c469015-468764 [Hydrocarboniclastica marina]
ATGGATGCCATTAGCTACACAGCCGCTAGAACCAATCTGGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCCCCCGT
GATCATCACCCGGAGCAAGTCGCCGTCCGTGGTGATGATCTCCCTGGAGGACTACGAGGCGCTGCAAGAAACCGCATACC
TCCTGCGCGCGCCGAAAAACGCCCGGCGTCTGCTGGAAGCCGTTGCCGAGCTGGAGCAAGGCGGTGGCCAAGAAAAGGAA
CTTCTTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References