Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 36829..37390 Replicon plasmid pYEE5
Accession NZ_CP031083
Organism Paracoccus yeei strain CCUG 32053

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PY32053_RS22535 Protein ID WP_120445305.1
Coordinates 36829..37104 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PY32053_RS22540 Protein ID WP_080623172.1
Coordinates 37097..37390 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY32053_RS23400 31855..32022 + 168 WP_158595053.1 hypothetical protein -
PY32053_RS23110 32303..32959 - 657 WP_147405621.1 hypothetical protein -
PY32053_RS22520 32959..33678 - 720 WP_080623169.1 hypothetical protein -
PY32053_RS22525 34443..34991 + 549 WP_158595054.1 plasmid mobilization relaxosome protein MobC -
PY32053_RS22530 34984..36783 + 1800 WP_147405623.1 relaxase/mobilization nuclease domain-containing protein -
PY32053_RS22535 36829..37104 - 276 WP_120445305.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PY32053_RS22540 37097..37390 - 294 WP_080623172.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PY32053_RS22545 37503..39614 - 2112 WP_147405624.1 type IV secretory system conjugative DNA transfer family protein -
PY32053_RS22550 39562..40551 - 990 WP_120445260.1 Flp pilus assembly complex ATPase component TadA -
PY32053_RS22555 40551..41852 - 1302 WP_158595055.1 TrbI/VirB10 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..74143 74143


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10204.87 Da        Isoelectric Point: 6.4575

>T108392 WP_120445305.1 NZ_CP031083:c37104-36829 [Paracoccus yeei]
VPEIEWREPAVADLMAIVDYISDDNPRAALALMDEIQTKVAQLADHPKRCRPGRVAGTRELIVRPNYLVVYAETAAKVTV
LRVLHAAQMWP

Download         Length: 276 bp

>T108392 NZ_CP031083:c37104-36829 [Paracoccus yeei]
GTGCCTGAAATCGAATGGAGAGAACCGGCGGTTGCGGACCTGATGGCGATTGTCGATTACATCTCGGATGACAATCCCCG
CGCAGCCTTGGCCTTGATGGATGAGATCCAGACTAAGGTCGCGCAACTGGCGGACCATCCGAAACGCTGCCGCCCCGGCA
GGGTGGCAGGCACGCGGGAGCTGATCGTCAGGCCGAACTACCTTGTTGTCTATGCCGAAACTGCGGCTAAGGTCACCGTT
CTGCGTGTTCTTCACGCCGCACAGATGTGGCCGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10310.88 Da        Isoelectric Point: 9.9916

>AT108392 WP_080623172.1 NZ_CP031083:c37390-37097 [Paracoccus yeei]
MPARTAMLHVRVDSQLKTQATDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTAAPDAYDAWFRAKVQEALSDPRPGKPH
DQVVLEARALIDAKRRA

Download         Length: 294 bp

>AT108392 NZ_CP031083:c37390-37097 [Paracoccus yeei]
ATGCCGGCACGGACCGCGATGCTCCACGTTCGCGTGGACAGCCAGCTCAAGACACAAGCGACAGACGCCCTGGCCGGGGT
GGGATTAACGCTGTCCGATGCCGTACGCATTCTGCTGACCCGGGTTGCCGCTGAAGGCGGGCTGCCAGCGGGCCTCACCG
CGGCGCCAGACGCCTATGACGCCTGGTTTCGGGCCAAGGTGCAGGAAGCGCTGAGCGATCCACGCCCCGGAAAGCCGCAT
GATCAGGTTGTCTTGGAAGCGCGCGCGCTGATCGATGCAAAACGCCGTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References