Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1948831..1948975 Replicon chromosome
Accession NZ_CP031061
Organism Klebsiella variicola strain GN02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1948867..1948969 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1948831..1948975 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DUZ89_RS09380 1943961..1946021 + 2061 WP_185185875.1 oligopeptidase B -
DUZ89_RS09385 1946025..1946684 - 660 WP_012541259.1 exodeoxyribonuclease X -
DUZ89_RS09390 1946763..1946993 - 231 WP_012541260.1 DNA polymerase III subunit theta -
DUZ89_RS09395 1947107..1947481 + 375 WP_008804269.1 CopC domain-containing protein YobA -
DUZ89_RS09400 1947485..1948354 + 870 WP_185185876.1 copper homeostasis membrane protein CopD -
DUZ89_RS09405 1948371..1948709 + 339 WP_008804271.1 YebY family protein -
- 1948831..1948975 - 145 - - Antitoxin
- 1948867..1948969 + 103 - - Toxin
DUZ89_RS09410 1949354..1949497 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
DUZ89_RS09415 1949601..1950569 - 969 WP_162493241.1 VirK/YbjX family protein -
DUZ89_RS09420 1950725..1951378 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
DUZ89_RS09425 1951375..1951566 - 192 WP_002911395.1 YebW family protein -
DUZ89_RS09430 1951664..1951903 - 240 WP_002911393.1 YebV family protein -
DUZ89_RS09435 1952019..1953452 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T108368 NZ_CP031061:1948867-1948969 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT108368 NZ_CP031061:c1948975-1948831 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References