Detailed information of TA system TA108362

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4689436..4691102
• Replicon: chromosome
• Accession: NZ_CP031059
• Organism: Xanthomonas axonopodis pv. commiphoreae strain LMG26789

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: Xcom_RS20945
• Protein ID: WP_122273444.1
• Coordinates: 4689436..4690788 (+)
• Length: 451 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: A0A3G2WC15
• Locus tag: Xcom_RS20950
• Protein ID: WP_033837358.1
• Coordinates: 4690806..4691102 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Xcom_RS20930	4685318..4686868	+	1551	WP_206212883.1	hypothetical protein	-
Xcom_RS20935	4687221..4688072	+	852	WP_080721286.1	hypothetical protein	-
Xcom_RS20940	4688539..4689375	+	837	WP_029820580.1	restriction endonuclease	-
Xcom_RS20945	4689436..4690788	+	1353	WP_122273444.1	zeta toxin family protein	Toxin
Xcom_RS20950	4690806..4691102	+	297	WP_033837358.1	hypothetical protein	Antitoxin
Xcom_RS20955	4691617..4692050	+	434	Protein_3884	hypothetical protein	-
Xcom_RS20960	4692220..4692696	-	477	WP_011349170.1	nuclear transport factor 2 family protein	-
Xcom_RS20965	4692760..4693329	-	570	WP_011349171.1	TetR/AcrR family transcriptional regulator	-
Xcom_RS20970	4693446..4694018	-	573	WP_057682233.1	TetR/AcrR family transcriptional regulator	-
Xcom_RS20975	4694102..4694845	+	744	WP_122273445.1	glucose 1-dehydrogenase	-
Xcom_RS20980	4695211..4695729	-	519	WP_122273610.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (180-320)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 451 a.a.
• Molecular weight: 48383.32 Da
• Isoelectric Point: 6.3533

>T108362 WP_122273444.1 NZ_CP031059:4689436-4690788 [Xanthomonas axonopodis pv. commiphoreae]
VGVRVAVRIATNVAESVGLYFLGLWTFFNMKNKIGIAGTAGLFTSHVPFDDAESKGVQAESSQAAPEYKFQTQLDNLPAR
PASSKSSNTTHAYVHASPPHSVPIAGASTAAVTHQQATQLKGTDELYGLGNLPSSGPGRWEYLANPENWHPERRKLHEKL
LDEARSSALTLAESLERDGCQPTLFALRGNTATGKTRIATKKIPALAAALEKTGGKGCINPDVFKSSLAKSEAGAKIFSS
AQVHNESCFLADHFEDGLRSQRTGSGAIASIVVDKRLARAYEIDSYIELAKETGRKVELCDIDAPLENSLTGVLQRKPEG
EDPRPPYPVVSSGFVAVRSNRMSVIDRFIADPSLGNYRLFGTAEDGKKVMVASVMGGELSVEDADLYEKITSPQSSVTGD
LADKIIDNELIDRLTNNIDDPERAANTRAALEKYNGKSWSAALAAHSELI

Nucleotide

• Length: 1353 bp

>T108362 NZ_CP031059:4689436-4690788 [Xanthomonas axonopodis pv. commiphoreae]
GTGGGTGTGCGAGTCGCGGTTCGAATCGCGACTAATGTTGCAGAGTCAGTCGGACTGTATTTTCTTGGACTCTGGACATT
TTTTAACATGAAAAACAAGATAGGCATTGCTGGCACAGCCGGGCTTTTTACTTCTCATGTTCCTTTCGATGACGCAGAAT
CCAAAGGCGTCCAAGCTGAGTCATCACAAGCGGCGCCGGAGTATAAATTCCAGACCCAGCTTGATAATTTGCCAGCTAGA
CCCGCTAGTTCGAAGAGCAGCAACACCACTCATGCTTATGTTCATGCATCGCCGCCGCATTCGGTGCCGATCGCAGGTGC
ATCGACCGCCGCGGTGACACATCAACAGGCTACTCAGCTTAAAGGCACCGATGAGTTATATGGTTTGGGCAACCTCCCAT
CTTCTGGTCCGGGGCGATGGGAGTATCTGGCGAATCCGGAGAACTGGCATCCGGAGCGCCGTAAGTTGCACGAAAAGCTA
TTAGATGAAGCACGATCTTCGGCCTTGACCCTGGCAGAATCTCTTGAGCGCGATGGCTGCCAACCGACATTGTTTGCGTT
GCGCGGAAACACTGCCACGGGTAAGACGCGGATAGCCACAAAAAAAATTCCAGCTCTCGCCGCAGCTCTGGAGAAGACTG
GTGGAAAAGGTTGCATCAATCCAGATGTATTCAAGAGTTCGCTTGCGAAGTCGGAGGCCGGCGCCAAGATATTTAGCTCG
GCGCAAGTTCATAACGAATCATGTTTTCTTGCTGACCATTTTGAAGACGGGCTTCGCTCTCAAAGGACGGGCAGCGGTGC
AATCGCTAGCATTGTTGTCGACAAGCGCTTGGCAAGGGCGTACGAAATCGACAGCTATATAGAACTAGCCAAAGAAACAG
GTCGAAAAGTTGAATTGTGCGATATCGATGCACCCCTTGAGAATTCTTTGACGGGAGTTTTGCAACGGAAACCTGAAGGT
GAAGATCCTAGGCCTCCTTACCCTGTAGTCTCGAGTGGATTTGTGGCCGTACGAAGCAATAGAATGAGTGTGATAGACAG
GTTCATCGCCGATCCGAGCCTGGGAAACTATCGACTATTCGGAACAGCCGAGGATGGTAAGAAGGTCATGGTTGCTAGCG
TCATGGGCGGTGAGTTGAGTGTAGAGGATGCTGATTTATATGAAAAGATAACGTCCCCGCAGTCCTCGGTTACCGGTGAT
TTGGCTGATAAGATAATCGACAATGAATTGATTGATCGTCTGACAAATAATATAGATGATCCCGAGCGCGCGGCGAATAC
GCGAGCCGCGCTGGAAAAATATAACGGCAAGTCGTGGTCGGCCGCGCTAGCTGCTCATAGCGAGCTAATTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11371.03 Da
• Isoelectric Point: 6.4773

>AT108362 WP_033837358.1 NZ_CP031059:4690806-4691102 [Xanthomonas axonopodis pv. commiphoreae]
MKTLKGAEALEFHKKLKERNEALHASDIASALVRADAVGKERFDLEELEKLCDTSSAGRLTDVKERRDIYERMYYVEYPK
IMTLKEFARIVETLSSWS

Nucleotide

• Length: 297 bp

>AT108362 NZ_CP031059:4690806-4691102 [Xanthomonas axonopodis pv. commiphoreae]
ATGAAAACTTTGAAAGGCGCAGAGGCGCTCGAATTCCATAAGAAGCTTAAGGAACGCAATGAAGCCTTACATGCTTCCGA
TATCGCGTCAGCATTAGTACGCGCCGATGCCGTCGGCAAGGAACGGTTTGATCTCGAGGAACTGGAAAAACTTTGCGATA
CCAGTAGTGCGGGGCGCCTTACTGATGTGAAAGAGCGCCGCGACATATATGAGCGGATGTACTACGTCGAGTATCCTAAA
ATTATGACGTTAAAGGAATTTGCTCGTATCGTTGAGACACTTTCCTCTTGGTCATGA

Structures

Antitoxin

• AlphaFold DB: A0A3G2WC15