108361

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3636906..3637267 Replicon chromosome
Accession NZ_CP031059
Organism Xanthomonas axonopodis pv. commiphoreae strain LMG26789

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag Xcom_RS15995 Protein ID WP_005914328.1
Coordinates 3636906..3637040 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q3BN31
Locus tag Xcom_RS16000 Protein ID WP_011348912.1
Coordinates 3637115..3637267 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Xcom_RS15980 3633939..3634961 - 1023 WP_014091330.1 MBL fold metallo-hydrolase -
Xcom_RS15985 3635012..3636301 - 1290 WP_122273167.1 tryptophan--tRNA ligase -
Xcom_RS15990 3636468..3636677 - 210 WP_003486601.1 CsbD family protein -
Xcom_RS15995 3636906..3637040 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
Xcom_RS16000 3637115..3637267 - 153 WP_011348912.1 entericidin A/B family lipoprotein Antitoxin
Xcom_RS16005 3637374..3638297 - 924 WP_008576436.1 arginase -
Xcom_RS16010 3638618..3639070 + 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
Xcom_RS16015 3639134..3639493 + 360 WP_003486613.1 hypothetical protein -
Xcom_RS16020 3639590..3640507 + 918 WP_008576439.1 hypothetical protein -
Xcom_RS16025 3640504..3641046 + 543 WP_003486615.1 GTPase -
Xcom_RS16035 3641517..3642197 + 681 WP_014091332.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T108361 WP_005914328.1 NZ_CP031059:c3637040-3636906 [Xanthomonas axonopodis pv. commiphoreae]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T108361 NZ_CP031059:c3637040-3636906 [Xanthomonas axonopodis pv. commiphoreae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5123.06 Da        Isoelectric Point: 8.2782

>AT108361 WP_011348912.1 NZ_CP031059:c3637267-3637115 [Xanthomonas axonopodis pv. commiphoreae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT108361 NZ_CP031059:c3637267-3637115 [Xanthomonas axonopodis pv. commiphoreae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2W7I0

References