Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 70048..70595 Replicon chromosome
Accession NZ_CP031059
Organism Xanthomonas axonopodis pv. commiphoreae strain LMG26789

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2W0H9
Locus tag Xcom_RS00300 Protein ID WP_039418332.1
Coordinates 70293..70595 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag Xcom_RS00295 Protein ID WP_008574056.1
Coordinates 70048..70305 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Xcom_RS00280 65193..66650 - 1458 WP_071117536.1 ribonuclease H-like domain-containing protein -
Xcom_RS00285 66647..69142 - 2496 WP_162998369.1 DEAD/DEAH box helicase -
Xcom_RS00290 69320..69982 + 663 WP_011345814.1 hemolysin III family protein -
Xcom_RS00295 70048..70305 + 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Xcom_RS00300 70293..70595 + 303 WP_039418332.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Xcom_RS00310 70778..71677 - 900 WP_065628423.1 SDR family NAD(P)-dependent oxidoreductase -
Xcom_RS00315 71737..72474 - 738 WP_122272041.1 SDR family oxidoreductase -
Xcom_RS00320 72600..72743 + 144 Protein_60 LysR family transcriptional regulator -
Xcom_RS00325 73511..74616 + 1106 WP_122272042.1 IS3 family transposase -
Xcom_RS00335 75352..75540 - 189 WP_008575250.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11523.36 Da        Isoelectric Point: 9.0231

>T108360 WP_039418332.1 NZ_CP031059:70293-70595 [Xanthomonas axonopodis pv. commiphoreae]
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T108360 NZ_CP031059:70293-70595 [Xanthomonas axonopodis pv. commiphoreae]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCGGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTTGAGCAATTAATTGAACACCCCGACAGCGGAAGCCGGC
CACAGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCCCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT108360 WP_008574056.1 NZ_CP031059:70048-70305 [Xanthomonas axonopodis pv. commiphoreae]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp

>AT108360 NZ_CP031059:70048-70305 [Xanthomonas axonopodis pv. commiphoreae]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W0H9

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References