Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5075653..5077370 Replicon chromosome
Accession NZ_CP031058
Organism Stenotrophomonas maltophilia strain SM 866

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag DUW70_RS23785 Protein ID WP_151608097.1
Coordinates 5075653..5076303 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag DUW70_RS23790 Protein ID WP_151608098.1
Coordinates 5076303..5077370 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DUW70_RS23775 5071217..5074432 + 3216 WP_151608095.1 type I restriction endonuclease subunit R -
DUW70_RS23780 5074425..5075660 + 1236 WP_189720288.1 SH3 domain-containing protein -
DUW70_RS23785 5075653..5076303 + 651 WP_151608097.1 DUF4433 domain-containing protein Toxin
DUW70_RS23790 5076303..5077370 + 1068 WP_151608098.1 macro domain-containing protein Antitoxin
DUW70_RS23795 5077528..5078733 - 1206 WP_189720289.1 tyrosine-type recombinase/integrase -
DUW70_RS23800 5078918..5080267 - 1350 WP_189720290.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 24956.40 Da        Isoelectric Point: 7.9769

>T108359 WP_151608097.1 NZ_CP031058:5075653-5076303 [Stenotrophomonas maltophilia]
MANHYPNLNPEKALIWRIVHRDNLSWILDNGLHCGNGGMQAPGWVSIGNPELIDKRANHPVPLPPGGFLNDYVPFYFTPF
SPMLRNIHTGWGGIQRRPNEEIVILVSSLHHVAAQGWPFLFTDSHAYYRWANFYSDLTGLNKIDWPLLQARDFRRDPEDP
AKFERYQAEALVQRHLPINGLLGIVCYTDNLRQAIERQVQARNLNLPVYARTGWYF

Download         Length: 651 bp

>T108359 NZ_CP031058:5075653-5076303 [Stenotrophomonas maltophilia]
ATGGCTAACCATTACCCGAATCTCAATCCAGAGAAGGCGCTGATCTGGCGCATCGTTCACCGCGACAACTTGTCGTGGAT
TCTGGACAATGGTCTGCACTGTGGCAACGGCGGTATGCAGGCTCCGGGCTGGGTGAGCATCGGCAACCCTGAACTGATCG
ACAAGCGCGCCAATCATCCTGTGCCACTGCCGCCCGGTGGTTTCCTGAACGACTACGTGCCGTTCTACTTCACCCCGTTT
TCGCCGATGCTGCGCAACATCCATACTGGTTGGGGCGGCATTCAGCGGAGGCCCAACGAGGAGATCGTAATCCTTGTTTC
CAGCCTGCATCACGTCGCAGCACAGGGGTGGCCGTTCCTGTTCACCGATAGCCACGCCTACTACCGGTGGGCAAACTTCT
ATTCCGATTTGACCGGTCTCAACAAGATCGACTGGCCGCTGCTTCAGGCGCGGGATTTCCGGCGCGATCCGGAAGACCCT
GCCAAGTTCGAGCGGTATCAGGCCGAGGCGCTGGTTCAGCGGCACCTTCCGATCAATGGCTTGCTCGGCATTGTGTGCTA
TACAGATAATCTGAGGCAGGCCATCGAGCGGCAGGTTCAGGCACGAAATCTGAACCTGCCGGTCTATGCCCGCACCGGGT
GGTACTTCTGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 39778.80 Da        Isoelectric Point: 6.3998

>AT108359 WP_151608098.1 NZ_CP031058:5076303-5077370 [Stenotrophomonas maltophilia]
MITFTQGNLLEARAEALVNTVNTVGVMGKGIALMFKERFADNFRRYAAACKAKEVCTGKMFVTEVRELDGPRWIVNFPTK
QHWRGDSKMEWITEGLQDLRRFLIDNKVKSIAIPPLGAGNGGLDWAEVRPHIEEALAGLDTDIIVFEPTQKYQNVAKRTG
VEKLTPTRALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERASLTPLDLRFVPHKYGPYADRLRHLLEGLDGSYLHCD
KRIGDADPLDVIWFDDGRKTFVQTYLKSEAKDYVPALEATAALIDGFESPYGMELLATVDWLLSQEGIAPTVPAVREGLH
HWGGGPGAAARKERLFDDRALSIALERLAPSAVAV

Download         Length: 1068 bp

>AT108359 NZ_CP031058:5076303-5077370 [Stenotrophomonas maltophilia]
ATGATCACATTTACTCAAGGCAACCTACTTGAAGCCCGCGCCGAAGCGCTGGTCAACACCGTCAACACCGTGGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTTGCCGACAACTTCCGTCGCTATGCCGCTGCTTGCAAAGCCAAGG
AAGTGTGCACCGGCAAGATGTTCGTCACTGAAGTGCGCGAACTGGACGGCCCGCGCTGGATCGTGAACTTTCCGACCAAG
CAGCACTGGCGCGGCGATTCCAAGATGGAATGGATCACCGAAGGGCTGCAAGATCTACGCCGTTTCCTGATCGACAACAA
GGTCAAGTCCATCGCCATCCCGCCTCTGGGTGCAGGCAATGGCGGGCTGGACTGGGCCGAGGTGCGCCCTCATATCGAGG
AAGCACTGGCTGGCCTCGACACCGACATCATTGTGTTCGAGCCGACCCAGAAATACCAAAACGTCGCCAAGCGCACGGGC
GTGGAGAAGCTGACTCCAACTCGCGCCCTGATCGCCGAACTGGTGCGCCGCTATTGGGTGCTGGGCATGGAGTGCAGCTT
GCTCGAAATCCAGAAGTTGGCGTGGTTCCTTGAACGCTCCATCGAGCGCGCGAGTCTGACGCCGCTGGATTTGCGCTTTG
TGCCGCACAAGTACGGCCCCTACGCCGACCGCTTGCGTCACCTGCTGGAAGGACTGGATGGCAGTTACCTCCACTGCGAC
AAGCGCATCGGCGACGCTGACCCGCTGGACGTGATCTGGTTCGACGACGGACGCAAGACCTTCGTTCAGACCTATCTCAA
GAGCGAAGCCAAGGACTATGTCCCAGCACTGGAAGCCACGGCAGCACTGATCGACGGCTTCGAGTCGCCCTACGGCATGG
AACTGCTAGCCACGGTGGACTGGCTGCTGTCGCAGGAAGGCATTGCCCCAACGGTGCCCGCCGTGCGCGAAGGGCTGCAT
CACTGGGGCGGCGGCCCGGGCGCGGCAGCCCGCAAGGAGCGGCTGTTTGACGACCGAGCACTAAGCATCGCGTTGGAGCG
GCTGGCACCGAGTGCGGTGGCGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References