Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 772326..773794 Replicon chromosome
Accession NZ_CP031058
Organism Stenotrophomonas maltophilia strain SM 866

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag DUW70_RS03590 Protein ID WP_189721202.1
Coordinates 772326..773192 (-) Length 289 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag DUW70_RS03595 Protein ID WP_088024269.1
Coordinates 773192..773794 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DUW70_RS03570 768340..769059 - 720 WP_189720570.1 metal-dependent hydrolase -
DUW70_RS03575 769194..769562 - 369 WP_041864472.1 YraN family protein -
DUW70_RS03580 769552..771273 - 1722 WP_094000431.1 penicillin-binding protein activator -
DUW70_RS03585 771355..772173 + 819 WP_189720571.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
DUW70_RS03590 772326..773192 - 867 WP_189721202.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DUW70_RS03595 773192..773794 - 603 WP_088024269.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
DUW70_RS03605 774498..774977 - 480 WP_107432417.1 DM13 domain-containing protein -
DUW70_RS03610 775339..776127 - 789 WP_149908781.1 NRDE family protein -
DUW70_RS03615 776451..776897 + 447 WP_004143635.1 division/cell wall cluster transcriptional repressor MraZ -
DUW70_RS03620 776912..777880 + 969 WP_189720572.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
DUW70_RS03625 777877..778140 + 264 WP_005412242.1 cell division protein FtsL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-267)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-53)


Sequences

Toxin        


Download         Length: 289 a.a.        Molecular weight: 32350.21 Da        Isoelectric Point: 7.0433

>T108358 WP_189721202.1 NZ_CP031058:c773192-772326 [Stenotrophomonas maltophilia]
IPSPTPPHRVASIRQRLLDLARKQGEDFQFVLDRFAVERLLYRLSASRYRNQFLLKGAMLFAVWFDAPHRPTRDADFLGS
GSAEPDRLLHIALSLCGMPGDDGLRFDPGSIVIEAIREEATYEGLRMRLIAHLGRARCHVQWDVGFGDAVITPPPEITYP
VILEGFPPACLRVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALIREDAMDRPHLVAAIGATFDRRRTPAPTPLPYGL
TQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTPVQS

Download         Length: 867 bp

>T108358 NZ_CP031058:c773192-772326 [Stenotrophomonas maltophilia]
ATCCCCTCTCCAACACCTCCCCACCGCGTTGCTTCCATCCGGCAACGGCTGCTCGATCTCGCACGCAAGCAGGGTGAGGA
CTTTCAGTTCGTGCTGGACAGGTTCGCCGTTGAGCGCCTGCTCTACCGGCTCTCCGCTTCTCGATACCGCAACCAGTTCC
TGCTGAAGGGTGCCATGCTGTTCGCAGTGTGGTTCGACGCGCCGCACCGCCCTACACGGGATGCCGATTTCCTGGGATCC
GGCAGCGCTGAGCCCGATCGCCTGCTACATATCGCACTTTCGCTCTGTGGAATGCCCGGGGACGACGGCCTGCGCTTCGA
TCCAGGCAGCATCGTCATCGAGGCCATACGTGAAGAAGCCACGTACGAGGGGCTGCGCATGCGCCTGATCGCACATCTGG
GCCGGGCACGCTGCCATGTGCAGTGGGACGTCGGGTTTGGCGACGCGGTGATCACCCCGCCGCCGGAAATCACCTATCCG
GTGATTCTGGAAGGATTCCCTCCAGCCTGCCTGCGCGTCTATCCACGCGAAACCGTGTTTGCCGAAAAGCTCGAGGCTAT
AGCGGCACTGGGCATCGCTAACAGCAGGATGAAGGACTTCTTCGACTTGCTGGCACTGATCCGCGAAGACGCCATGGATC
GCCCGCACCTTGTTGCGGCCATTGGCGCGACGTTTGATCGACGAAGGACCCCGGCGCCAACGCCCCTGCCCTACGGACTG
ACTCAGTCATTCGCCGCAGATACCCAGAAGCAGACCCAGTGGCGCGCCTTCCTGCGCAGGAATCGCCTGATCGCGCCGGA
CCTCTCTTCGGTGATTGCCGAGATTGCCGACTATCTGGACACCCTCGACACACCCGTACAGTCCTGA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22232.96 Da        Isoelectric Point: 11.2557

>AT108358 WP_088024269.1 NZ_CP031058:c773794-773192 [Stenotrophomonas maltophilia]
MGNAEAKARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERKSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSATTLNAGLEERRVGGRLIYVSNAAKTVVDCFKFRNLVGLDV
ALEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp

>AT108358 NZ_CP031058:c773794-773192 [Stenotrophomonas maltophilia]
ATGGGAAACGCCGAGGCCAAGGCACGAAAGCTATTGCGACGCGCAGGCACCCTGCGCGCCCGCGAACTGGTGACTGCCGG
GATCGCCCGCGCCCAACTGACCCGCCTGGTCGAGGCAGGCGCACTGATCCGGTTGTCCCGTGGCGTCTACGCGTTGGCGG
AAAGAAAGAGCGACGACACCGATGATGGACTGCGGATCATTGCAGAACGCCTGCCACACCCCCGTCTATGCCTGCTGAGT
GCCCTGCGCCTGCATGGCCTGACCACCCAGGCACCATTCGAACGCTGGGTCTCCATCGGCAACAGCGACCGCGTTCCGCG
GATCGACTGGCCGCCCCTCCGTGTGGTCCGCATGTCGGCAACGACCCTCAATGCGGGGCTGGAAGAACGTCGCGTAGGCG
GACGTCTCATATACGTCAGCAACGCTGCCAAAACCGTCGTCGATTGCTTCAAGTTCCGCAATCTCGTAGGGCTTGATGTC
GCACTTGAAGCCCTGCGTGACGCGCTTCACAGCCGTGCAACCACGCCGGATGCGTTGATGGAGTATGCGCGGATCTGCCG
CGTTGCCAGACTGATGAGACCGTACCTCGATGCCCTGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References