Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1930793..1931346 Replicon chromosome
Accession NZ_CP031056
Organism Vibrio splendidus strain Vibrio sp

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DUN60_RS24145 Protein ID WP_114635711.1
Coordinates 1930793..1931086 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DUN60_RS24150 Protein ID WP_065206367.1
Coordinates 1931086..1931346 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DUN60_RS24120 1926253..1927587 + 1335 WP_114635707.1 guanine deaminase -
DUN60_RS24125 1927875..1928756 + 882 WP_114635708.1 AEC family transporter -
DUN60_RS24130 1928875..1929258 - 384 WP_114635709.1 carboxymuconolactone decarboxylase family protein -
DUN60_RS24135 1929319..1929675 - 357 WP_114635710.1 MerR family transcriptional regulator -
DUN60_RS24140 1929720..1930238 - 519 WP_065206365.1 hypothetical protein -
DUN60_RS24145 1930793..1931086 - 294 WP_114635711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DUN60_RS24150 1931086..1931346 - 261 WP_065206367.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DUN60_RS24155 1931589..1931912 + 324 WP_114635712.1 hypothetical protein -
DUN60_RS24165 1932252..1932683 - 432 WP_114635714.1 TetR family transcriptional regulator -
DUN60_RS24170 1932945..1934759 - 1815 WP_114635715.1 hypothetical protein -
DUN60_RS24175 1935211..1935768 - 558 WP_162808250.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
DUN60_RS24180 1935761..1935970 - 210 WP_114635717.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-50)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11355.11 Da        Isoelectric Point: 9.8774

>T108351 WP_114635711.1 NZ_CP031056:c1931086-1930793 [Vibrio splendidus]
MTHYKLSSAAQSDLIEIRRYTLERWGQTQWTAYFSELKQSMELLASNKLLGIAVSELGQDYFRFPLKHHVIYYTRKQEHI
IIAAVLGKHMSPAKHFS

Download         Length: 294 bp

>T108351 NZ_CP031056:c1931086-1930793 [Vibrio splendidus]
ATGACGCACTATAAGCTTTCTTCTGCAGCGCAATCTGATCTCATTGAGATTCGTCGCTATACATTAGAGCGATGGGGGCA
AACACAATGGACCGCTTACTTTTCAGAATTAAAGCAATCAATGGAATTACTGGCTAGCAATAAGTTGCTCGGCATAGCGG
TTTCAGAGTTGGGGCAAGATTACTTCCGTTTTCCTTTAAAGCACCATGTGATTTATTACACTCGAAAACAAGAGCACATC
ATTATTGCCGCGGTTCTTGGTAAGCACATGTCTCCGGCTAAGCACTTTTCATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9609.99 Da        Isoelectric Point: 4.3867

>AT108351 WP_065206367.1 NZ_CP031056:c1931346-1931086 [Vibrio splendidus]
MQSLTANTAKTKFGDLLMKVQREPIQINKNGSPVAVMMSCEEYEQLEAMKLMFVKSRFEQAEADALSGNLVDGNDFMNAL
DQGKFD

Download         Length: 261 bp

>AT108351 NZ_CP031056:c1931346-1931086 [Vibrio splendidus]
ATGCAATCACTTACAGCTAATACAGCTAAAACCAAATTTGGCGATTTGTTGATGAAAGTTCAACGTGAACCCATACAAAT
CAATAAGAACGGCTCGCCAGTTGCAGTGATGATGTCTTGTGAAGAGTATGAGCAACTTGAAGCCATGAAATTGATGTTCG
TTAAATCACGCTTCGAACAAGCAGAAGCCGATGCTTTATCAGGTAACCTAGTCGATGGTAACGACTTCATGAATGCACTG
GACCAAGGTAAGTTTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References