Detailed information of TA system TA108306

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 1473510..1474159
• Replicon: chromosome
• Accession: NZ_CP031011
• Organism: Acinetobacter johnsonii strain LXL_C1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: DT536_RS07145
• Protein ID: WP_058870345.1
• Coordinates: 1473773..1474159 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9CU98
• Locus tag: DT536_RS07140
• Protein ID: WP_004977895.1
• Coordinates: 1473510..1473767 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DT536_RS07120	1469128..1469493	+	366	WP_004691290.1	50S ribosomal protein L17	-
DT536_RS07125	1469689..1471179	+	1491	WP_058870348.1	NAD(P)/FAD-dependent oxidoreductase	-
DT536_RS07130	1471318..1472109	+	792	WP_114392663.1	alpha/beta hydrolase	-
DT536_RS07135	1472145..1473317	-	1173	WP_058870346.1	acyl-CoA dehydrogenase family protein	-
DT536_RS07140	1473510..1473767	+	258	WP_004977895.1	succinate dehydrogenase assembly factor 2	Antitoxin
DT536_RS07145	1473773..1474159	+	387	WP_058870345.1	hypothetical protein	Toxin
DT536_RS07150	1474680..1475717	+	1038	WP_004977889.1	hypothetical protein	-
DT536_RS07155	1475789..1476361	+	573	WP_058870344.1	rhombosortase	-
DT536_RS07160	1476544..1478826	+	2283	WP_058870343.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-127)

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15293.27 Da
• Isoelectric Point: 10.4418

>T108306 WP_058870345.1 NZ_CP031011:1473773-1474159 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPLGLWLIALVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQNFRAKPMLVWCDQLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T108306 NZ_CP031011:1473773-1474159 [Acinetobacter johnsonii]
ATGGAACATCGTCATTTTCAACTTAAACCCAGCCGTCTGGCTTATGTGTTTCAGTTGTCGATTTATGCCGTTCTGATGCT
GGTCTTGTATCAGCTACTTCCTTTAGGACTGTGGCTGATCGCTTTGGTTGCAGGCTTTGTGCTGTATTTGTTTTTTCTAC
GTGGGCCGCAACATTTTCAGCTTCAGCATTTAGATGGCCGTGATTGGTCTTTGTCACTTCAGAAACAAACCAATGTGCAA
CGAGTGCAAATCAGCCATATTGTTGATCATCGTGCTTATATTGTGATTTATTTTCAAAACTTTAGAGCAAAACCGATGTT
GGTTTGGTGTGATCAGTTGCCCATCACGCAATGGAAAGCCCTGAAAATACTCACTAAAATGCAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10181.71 Da
• Isoelectric Point: 4.7119

>AT108306 WP_004977895.1 NZ_CP031011:1473510-1473767 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT108306 NZ_CP031011:1473510-1473767 [Acinetobacter johnsonii]
ATGACTGAAGAAATGAGCCTAGAAGAGCGTAAAGTAATTTATCGTGCACGTCGTGGTTTAAAAGAAATTGATGTGTACTT
TGATCCTTATGTGAAAAATTATTATCTTCAGGCAGATCCTGCGGAAAAGGCCATGTTTGCGGCCTTGGTTGAACAAGAAG
ATCCAGATTTGTTGGATTGGTTTATGGAAGTTTCTGAGCCGCCACGCCCTGAAATGAAAACCTTGATTCAAAAATTAAAG
CATTATGTACACGGATAA

Structures

Antitoxin

• AlphaFold DB: N9CU98