Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1908997..1909577 Replicon chromosome
Accession NZ_CP031009
Organism Alcanivorax sp. ALC70

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ASALC70_RS10045 Protein ID WP_203105608.1
Coordinates 1908997..1909299 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ASALC70_RS10050 Protein ID WP_161385729.1
Coordinates 1909296..1909577 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASALC70_RS10025 (ASALC70_02038) 1905204..1905599 - 396 WP_161385725.1 hypothetical protein -
ASALC70_RS10030 (ASALC70_02039) 1905803..1906264 + 462 WP_260550802.1 ion transporter -
ASALC70_RS10035 (ASALC70_02040) 1906264..1906641 + 378 WP_260550804.1 ion transporter -
ASALC70_RS10040 1906718..1908903 - 2186 Protein_1968 OsmC domain/YcaO domain-containing protein -
ASALC70_RS10045 (ASALC70_02043) 1908997..1909299 - 303 WP_203105608.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ASALC70_RS10050 (ASALC70_02044) 1909296..1909577 - 282 WP_161385729.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ASALC70_RS10055 (ASALC70_02045) 1909643..1909873 - 231 WP_161385730.1 DUF6429 family protein -
ASALC70_RS10060 (ASALC70_02046) 1909957..1910271 - 315 WP_260550805.1 hypothetical protein -
ASALC70_RS10065 (ASALC70_02047) 1910374..1910817 - 444 WP_260550807.1 GAF domain-containing protein -
ASALC70_RS10070 (ASALC70_02048) 1910886..1911167 - 282 WP_256245461.1 type II toxin-antitoxin system RelE/ParE family toxin -
ASALC70_RS10075 (ASALC70_02049) 1911164..1911436 - 273 WP_256245462.1 ribbon-helix-helix protein, CopG family -
ASALC70_RS10080 (ASALC70_02050) 1911507..1911923 - 417 WP_260550808.1 DUF1294 domain-containing protein -
ASALC70_RS10085 (ASALC70_02051) 1912132..1912710 + 579 WP_260550810.1 sigma-70 family RNA polymerase sigma factor -
ASALC70_RS10090 (ASALC70_02052) 1912698..1913615 + 918 WP_161385736.1 FecR domain-containing protein -
ASALC70_RS10095 (ASALC70_02053) 1913827..1914387 + 561 WP_260550811.1 STN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1908997..1925823 16826


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11246.76 Da        Isoelectric Point: 4.4237

>T108300 WP_203105608.1 NZ_CP031009:c1909299-1908997 [Alcanivorax sp. ALC70]
MNIVWSPLALERVEDIALYIAEDNPGAADGWVDDIFAAVERLAAFPESGRIVPEVGARRIREVIVGQYRIIYSVKDRIDV
LTVRRSSQLLRSDEIHDGDP

Download         Length: 303 bp

>T108300 NZ_CP031009:c1909299-1908997 [Alcanivorax sp. ALC70]
ATGAACATCGTCTGGTCGCCGCTGGCCCTTGAGCGTGTCGAGGACATTGCTCTGTACATCGCCGAGGATAACCCCGGTGC
GGCGGATGGCTGGGTGGATGACATCTTCGCCGCCGTGGAACGGCTTGCGGCTTTCCCTGAGAGTGGCCGAATCGTGCCCG
AGGTGGGAGCCCGGCGTATCCGTGAAGTGATCGTCGGCCAGTATCGAATCATTTATAGCGTGAAAGACCGCATCGATGTA
TTGACGGTGCGGCGGAGCAGCCAGCTTCTGCGCTCCGATGAAATCCACGACGGCGATCCGTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10799.40 Da        Isoelectric Point: 6.8832

>AT108300 WP_161385729.1 NZ_CP031009:c1909577-1909296 [Alcanivorax sp. ALC70]
MPRVRVDEDIRPLSEFRAGVATFVRHIHETRRPMVLTQRGRGVAVLVDVHEYERMQERLEVLEEVYKAEEQIAVGDGIPH
QDAKARIKGRLLE

Download         Length: 282 bp

>AT108300 NZ_CP031009:c1909577-1909296 [Alcanivorax sp. ALC70]
ATGCCGCGAGTTCGAGTTGATGAAGACATCCGCCCGCTGTCCGAATTCCGGGCTGGGGTGGCCACCTTCGTGAGACACAT
CCACGAGACCCGGCGCCCCATGGTGCTCACCCAGCGCGGGCGTGGCGTGGCGGTGTTGGTGGACGTTCATGAGTATGAGC
GAATGCAGGAACGCCTGGAGGTGCTGGAGGAGGTCTATAAGGCCGAGGAGCAGATCGCCGTGGGGGACGGGATTCCCCAT
CAGGATGCCAAGGCCAGGATCAAGGGCCGATTGTTGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References