Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 746016..746563 Replicon chromosome
Accession NZ_CP031009
Organism Alcanivorax sp. ALC70

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ASALC70_RS03850 Protein ID WP_260550958.1
Coordinates 746324..746563 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ASALC70_RS03845 Protein ID WP_260549948.1
Coordinates 746016..746288 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASALC70_RS03815 742366..742788 - 423 WP_260550957.1 anti-phage ZorAB system protein ZorA -
ASALC70_RS03820 (ASALC70_00773) 742877..743101 - 225 WP_260549938.1 hypothetical protein -
ASALC70_RS03825 (ASALC70_00774) 743182..743550 - 369 WP_260549940.1 HEPN domain-containing protein -
ASALC70_RS03830 (ASALC70_00776) 743696..744628 - 933 WP_260549942.1 metallophosphoesterase -
ASALC70_RS03835 (ASALC70_00777) 744807..745712 + 906 WP_260549946.1 WYL domain-containing protein -
ASALC70_RS03845 (ASALC70_00778) 746016..746288 + 273 WP_260549948.1 ribbon-helix-helix domain-containing protein Antitoxin
ASALC70_RS03850 (ASALC70_00779) 746324..746563 + 240 WP_260550958.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ASALC70_RS03855 746735..749275 + 2541 Protein_761 DNA mismatch repair protein MutS -
ASALC70_RS03860 (ASALC70_00783) 749505..749834 + 330 WP_161384470.1 ferredoxin family protein -
ASALC70_RS03865 (ASALC70_00784) 750476..750829 - 354 WP_256245166.1 Hpt domain-containing protein -
ASALC70_RS03870 (ASALC70_00785) 750998..751300 - 303 WP_260550959.1 DUF2064 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 706403..747073 40670


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-78)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9253.67 Da        Isoelectric Point: 9.6197

>T108299 WP_260550958.1 NZ_CP031009:746324-746563 [Alcanivorax sp. ALC70]
MVRLYEFLAVVNQPAAARTVQQLTAAPTSLLANPRIGERLDEFQPRSVRRILIGHYEMRYEVAGDTLYILRLWHTREDR

Download         Length: 240 bp

>T108299 NZ_CP031009:746324-746563 [Alcanivorax sp. ALC70]
ATGGTCAGGCTCTATGAGTTCCTGGCCGTGGTGAATCAGCCCGCCGCAGCCCGAACCGTCCAACAACTGACGGCCGCACC
GACGTCCTTATTAGCGAACCCGCGTATCGGAGAGCGGCTAGACGAATTCCAACCCAGAAGTGTGCGGCGAATTCTCATCG
GCCACTATGAGATGCGATATGAGGTTGCAGGCGATACGCTGTATATCCTCCGCCTGTGGCACACCCGCGAAGATCGGTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10117.13 Da        Isoelectric Point: 4.3998

>AT108299 WP_260549948.1 NZ_CP031009:746016-746288 [Alcanivorax sp. ALC70]
MSATTNTRSVTAHVPVDLADRIDEIATRLERSKNWIIRQALADWLDQEEERDRLTREALADVDAGHVIDHQAISDWADSL
STDSPLPAPR

Download         Length: 273 bp

>AT108299 NZ_CP031009:746016-746288 [Alcanivorax sp. ALC70]
ATGTCCGCAACCACCAACACCCGCTCCGTAACGGCCCATGTGCCTGTGGATCTAGCGGACCGGATCGATGAAATCGCCAC
GCGCTTGGAGCGATCCAAGAACTGGATCATCCGGCAAGCCCTGGCTGACTGGCTTGATCAGGAAGAAGAGCGCGACAGGC
TGACCCGCGAAGCGCTGGCCGATGTGGATGCCGGGCACGTGATCGACCATCAGGCCATTAGTGATTGGGCCGACAGCCTG
AGCACGGATTCACCGCTGCCCGCGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References