Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4152-relB/RHH(antitoxin)
Location 706403..707355 Replicon chromosome
Accession NZ_CP031009
Organism Alcanivorax sp. ALC70

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag ASALC70_RS03600 Protein ID WP_161385002.1
Coordinates 706792..707355 (-) Length 188 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ASALC70_RS03595 Protein ID WP_194297700.1
Coordinates 706403..706672 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASALC70_RS03575 (ASALC70_00733) 703510..704637 - 1128 WP_194297697.1 restriction endonuclease subunit S -
ASALC70_RS03580 (ASALC70_00734) 704634..706118 - 1485 WP_260549915.1 class I SAM-dependent DNA methyltransferase -
ASALC70_RS03585 (ASALC70_00735) 706129..706263 - 135 WP_256245169.1 hypothetical protein -
ASALC70_RS03590 (ASALC70_00736) 706260..706400 - 141 WP_194297699.1 hypothetical protein -
ASALC70_RS03595 (ASALC70_00737) 706403..706672 - 270 WP_194297700.1 CopG family ribbon-helix-helix protein Antitoxin
ASALC70_RS03600 (ASALC70_00738) 706792..707355 - 564 WP_161385002.1 PIN domain-containing protein Toxin
ASALC70_RS03605 (ASALC70_00739) 707355..707807 - 453 WP_194297702.1 helix-turn-helix domain-containing protein -
ASALC70_RS03610 708156..708395 + 240 WP_161385003.1 hypothetical protein -
ASALC70_RS03615 (ASALC70_00740) 708659..708862 - 204 WP_022990665.1 hypothetical protein -
ASALC70_RS03620 708904..709326 - 423 WP_022990666.1 cytochrome c -
ASALC70_RS03625 (ASALC70_00741) 709323..709988 - 666 WP_094625999.1 isoprenylcysteine carboxylmethyltransferase family protein -
ASALC70_RS03630 709981..710217 - 237 WP_260550954.1 DUF2933 domain-containing protein -
ASALC70_RS03635 (ASALC70_00742) 710289..710999 - 711 WP_260549916.1 hypothetical protein -
ASALC70_RS03640 710993..711358 - 366 WP_260549917.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 706403..747073 40670


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 188 a.a.        Molecular weight: 21027.06 Da        Isoelectric Point: 4.6720

>T108297 WP_161385002.1 NZ_CP031009:c707355-706792 [Alcanivorax sp. ALC70]
MRFSVIYDACVLYPAPLRDFLIRLALSGLFAARWSDDIQNEWSRNLLEDRPELAGQLPRTIELMNQAVPDCRVTGYENLI
AGLTLPDPDDRHVLAAAVVAGAQLIVTFNLRDFPEAVLARFGIEAVHPDDFVVQQFDLHEARVIETAKNHRGSLKKPPKG
VEEYLETLAAQGLVVTVDRLREYEGFI

Download         Length: 564 bp

>T108297 NZ_CP031009:c707355-706792 [Alcanivorax sp. ALC70]
ATGCGCTTTTCGGTCATCTACGACGCCTGCGTTTTGTACCCGGCTCCGCTCCGCGATTTTCTAATCCGGCTGGCGCTATC
GGGTTTGTTCGCAGCGAGATGGTCGGACGATATTCAGAACGAATGGTCCCGGAATCTGCTGGAGGACCGACCGGAACTCG
CCGGACAGCTGCCTCGCACCATCGAATTGATGAACCAGGCCGTGCCGGACTGCCGGGTTACCGGCTACGAAAACCTGATC
GCGGGGCTGACATTGCCAGACCCCGACGACAGACATGTGCTCGCGGCGGCCGTTGTGGCCGGTGCTCAACTGATCGTTAC
CTTTAACCTAAGAGATTTTCCAGAGGCCGTGCTGGCGAGGTTCGGAATAGAGGCAGTTCATCCGGATGATTTTGTTGTTC
AGCAGTTCGATCTTCACGAAGCAAGGGTTATTGAAACGGCGAAAAACCATAGGGGTTCGTTGAAAAAACCTCCGAAAGGG
GTGGAAGAGTATCTTGAGACGCTGGCGGCTCAGGGCCTGGTCGTGACCGTCGATAGGTTGCGGGAATATGAGGGCTTTAT
CTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10537.83 Da        Isoelectric Point: 9.0678

>AT108297 WP_194297700.1 NZ_CP031009:c706672-706403 [Alcanivorax sp. ALC70]
MATSIKIDDELKGRVRALASQRRRSPHWIMLEAIRQYVAREEAHESFKREALASWRSYRETGRRLTVQETNEWLESWGRD
DKAPPGCHE

Download         Length: 270 bp

>AT108297 NZ_CP031009:c706672-706403 [Alcanivorax sp. ALC70]
ATGGCAACCTCCATCAAAATTGACGACGAGCTGAAAGGCCGCGTCCGGGCACTGGCCAGCCAGCGCCGCCGCTCACCGCA
CTGGATCATGCTGGAAGCCATCAGGCAATATGTGGCCCGCGAAGAGGCCCATGAGAGTTTCAAGCGGGAAGCCCTGGCGT
CCTGGCGGTCCTACCGCGAGACCGGGCGTCGCCTCACGGTCCAGGAAACCAATGAGTGGCTGGAGTCCTGGGGCCGTGAC
GATAAGGCACCACCCGGGTGTCACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References