Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 697124..697755 Replicon chromosome
Accession NZ_CP031009
Organism Alcanivorax sp. ALC70

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ASALC70_RS03545 Protein ID WP_194297693.1
Coordinates 697124..697522 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ASALC70_RS03550 Protein ID WP_161384996.1
Coordinates 697522..697755 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASALC70_RS03535 (ASALC70_00726) 695398..696501 + 1104 WP_260549911.1 DUF2220 domain-containing protein -
ASALC70_RS03540 (ASALC70_00727) 696512..697111 + 600 WP_260549912.1 VTT domain-containing protein -
ASALC70_RS03545 (ASALC70_00728) 697124..697522 - 399 WP_194297693.1 type II toxin-antitoxin system VapC family toxin Toxin
ASALC70_RS03550 (ASALC70_00729) 697522..697755 - 234 WP_161384996.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
ASALC70_RS03555 (ASALC70_00730) 697855..699237 - 1383 WP_260549913.1 MFS transporter -
ASALC70_RS03560 699405..699668 + 264 WP_260550953.1 AraC family ligand binding domain-containing protein -
ASALC70_RS03565 (ASALC70_00731) 699644..700102 + 459 WP_260549914.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(9-56)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15176.36 Da        Isoelectric Point: 7.0758

>T108295 WP_194297693.1 NZ_CP031009:c697522-697124 [Alcanivorax sp. ALC70]
MLRYLLDTNIVIYVIKRRPMEVLEVFNRRAGEMAISTITEAELVHGAEKSQHREHNLRQVEDFTSRLEVLDYGRKAAAHY
GDIRADLERKGTPIGVNDLHLAAHARGEGLILVTNNMREFERVAGLRVENWL

Download         Length: 399 bp

>T108295 NZ_CP031009:c697522-697124 [Alcanivorax sp. ALC70]
ATGCTGCGCTATCTGCTTGATACCAACATCGTTATCTATGTGATCAAGCGGCGCCCGATGGAAGTCCTGGAGGTGTTCAA
TCGCCGCGCGGGGGAGATGGCCATCAGTACCATCACCGAAGCGGAGCTTGTTCACGGTGCCGAAAAAAGCCAGCACCGCG
AACATAACCTGCGTCAGGTCGAGGATTTCACGTCCCGCCTTGAGGTGCTGGATTACGGCCGCAAGGCGGCGGCTCACTAC
GGTGACATCCGCGCGGACCTGGAGCGCAAAGGGACGCCCATCGGCGTTAACGACCTGCACCTTGCCGCCCACGCACGCGG
TGAAGGGCTGATCCTGGTCACCAACAATATGCGCGAATTCGAGCGGGTGGCCGGGCTGCGCGTGGAGAATTGGCTTTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8878.86 Da        Isoelectric Point: 5.1231

>AT108295 WP_161384996.1 NZ_CP031009:c697755-697522 [Alcanivorax sp. ALC70]
MSTGSVFENNRTQAVRLPADSRFPNGVKRVRVRKVGRDRILSPVENTWDSFFLSEESVTDDFLPERASQEQPEREPL

Download         Length: 234 bp

>AT108295 NZ_CP031009:c697755-697522 [Alcanivorax sp. ALC70]
ATGAGTACGGGTTCCGTGTTTGAAAACAATCGCACCCAGGCTGTCCGTTTGCCGGCGGACTCCCGCTTTCCGAATGGCGT
TAAGCGGGTGCGGGTACGCAAGGTCGGCAGGGACCGGATTCTGTCACCGGTGGAGAACACCTGGGACAGTTTTTTCCTGT
CCGAGGAGAGTGTCACCGACGACTTTCTGCCCGAACGGGCCTCCCAGGAGCAGCCCGAACGGGAACCCTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References