Detailed information of TA system TA108294

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 550702..551266
• Replicon: chromosome
• Accession: NZ_CP031009
• Organism: Alcanivorax sp. ALC70

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ASALC70_RS02840
• Protein ID: WP_256245800.1
• Coordinates: 550702..550938 (-)
• Length: 79 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ASALC70_RS02845
• Protein ID: WP_161384787.1
• Coordinates: 550967..551266 (-)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ASALC70_RS02795 (ASALC70_00576)	545735..546070	+	336	WP_260549818.1	DUF3325 domain-containing protein	-
ASALC70_RS02800 (ASALC70_00577)	546187..546630	-	444	WP_260549819.1	gamma-glutamylcyclotransferase family protein	-
ASALC70_RS02805 (ASALC70_00578)	546830..547510	+	681	WP_194865873.1	hypothetical protein	-
ASALC70_RS02810 (ASALC70_00579)	547522..547899	-	378	WP_260549820.1	helix-turn-helix transcriptional regulator	-
ASALC70_RS02815 (ASALC70_00580)	547983..548297	-	315	WP_194865871.1	hypothetical protein	-
ASALC70_RS02820 (ASALC70_00581)	548445..548750	-	306	WP_260549821.1	DNA-binding transcriptional regulator	-
ASALC70_RS02825 (ASALC70_00582)	549069..549773	-	705	WP_194865870.1	NUDIX domain-containing protein	-
ASALC70_RS02830 (ASALC70_00583)	549863..550225	-	363	WP_260549822.1	transcriptional regulator	-
ASALC70_RS02835	550225..550524	-	300	WP_161384788.1	type II toxin-antitoxin system HigB family toxin	-
ASALC70_RS02840 (ASALC70_00584)	550702..550938	-	237	WP_256245800.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ASALC70_RS02845 (ASALC70_00585)	550967..551266	-	300	WP_161384787.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
ASALC70_RS02850 (ASALC70_00586)	551827..552540	+	714	WP_260549823.1	transposase	-
ASALC70_RS02855 (ASALC70_00587)	552537..553352	+	816	WP_260549824.1	type II secretion system protein N	-
ASALC70_RS02860 (ASALC70_00588)	553589..554263	+	675	WP_260549825.1	hypothetical protein	-
ASALC70_RS02865 (ASALC70_00589)	554335..554970	-	636	WP_260549826.1	DUF4351 domain-containing protein	-
ASALC70_RS02870 (ASALC70_00590)	555548..556207	+	660	WP_161384782.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-75)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (6-54)

Sequences

Toxin

Protein

• Length: 79 a.a.
• Molecular weight: 8903.29 Da
• Isoelectric Point: 4.3976

>T108294 WP_256245800.1 NZ_CP031009:c550938-550702 [Alcanivorax sp. ALC70]
MEILDYISDDNPLAAVALMDEIEEKVVRLLENPLIHRPGRVAGTRELVVRPNYIVVYACSEDHVEIIQILHAAQQWPL

Nucleotide

• Length: 237 bp

>T108294 NZ_CP031009:c550938-550702 [Alcanivorax sp. ALC70]
TTGGAGATACTGGATTACATCTCTGACGATAACCCTCTTGCCGCGGTGGCTTTGATGGATGAGATTGAAGAGAAAGTCGT
TCGCCTGCTGGAGAATCCGTTGATACATCGGCCTGGGCGTGTCGCAGGAACCCGGGAGTTGGTGGTGCGCCCGAACTACA
TCGTCGTCTACGCTTGTTCGGAGGACCACGTTGAGATCATCCAGATTTTGCATGCCGCTCAGCAGTGGCCGCTTTAG

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11149.78 Da
• Isoelectric Point: 7.2062

>AT108294 WP_161384787.1 NZ_CP031009:c551266-550967 [Alcanivorax sp. ALC70]
MAAETTMLHVRINEKLKGEAADTLAGLGLTVSDAVRILLTRVVRERGLPLGLTADPEFYDAWFKAKVREAMEDTRAAASH
DQVMDDARELIERKRQRKN

Nucleotide

• Length: 300 bp

>AT108294 NZ_CP031009:c551266-550967 [Alcanivorax sp. ALC70]
ATGGCCGCTGAAACGACGATGCTGCATGTGCGCATTAACGAGAAATTGAAAGGCGAAGCCGCCGATACTTTGGCCGGACT
GGGTTTGACGGTCTCGGATGCCGTACGGATCTTGCTGACTCGAGTGGTCAGGGAGCGTGGTTTGCCCCTCGGTCTGACCG
CTGATCCCGAGTTTTACGACGCTTGGTTCAAGGCAAAAGTCCGCGAGGCCATGGAAGACACCCGCGCGGCCGCTTCTCAT
GATCAGGTCATGGACGATGCAAGGGAGCTCATCGAAAGGAAACGACAGCGCAAGAATTAA