Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 549101..549636 Replicon chromosome
Accession NZ_CP030980
Organism Yersinia enterocolitica subsp. palearctica strain Y1

Toxin (Protein)


Gene name relE Uniprot ID A0A7U7FI46
Locus tag YEY1_RS02575 Protein ID WP_005156226.1
Coordinates 549349..549636 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U7FI63
Locus tag YEY1_RS02570 Protein ID WP_005156229.1
Coordinates 549101..549352 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YEY1_RS02545 544318..545202 + 885 WP_005156239.1 sugar ABC transporter permease -
YEY1_RS02550 545221..546060 + 840 WP_005156238.1 carbohydrate ABC transporter permease -
YEY1_RS02555 546072..547187 + 1116 WP_005156237.1 ABC transporter ATP-binding protein -
YEY1_RS02560 547201..548367 + 1167 WP_005156235.1 alginate lyase family protein -
YEY1_RS02565 548441..548893 + 453 WP_005181269.1 YhbP family protein -
YEY1_RS02570 549101..549352 + 252 WP_005156229.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
YEY1_RS02575 549349..549636 + 288 WP_005156226.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
YEY1_RS02580 549712..550341 + 630 WP_005175332.1 hypothetical protein -
YEY1_RS02585 550342..551109 - 768 WP_005156220.1 phosphonate metabolism protein PhnP -
YEY1_RS02590 551100..551678 - 579 Protein_483 ribose 1,5-bisphosphokinase -
YEY1_RS02595 551678..552826 - 1149 WP_005156213.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
YEY1_RS02600 552823..553557 - 735 WP_005156211.1 phosphonate C-P lyase system protein PhnL -
YEY1_RS02605 553571..554377 - 807 WP_005156209.1 phosphonate C-P lyase system protein PhnK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11002.07 Da        Isoelectric Point: 10.3544

>T108273 WP_005156226.1 NZ_CP030980:549349-549636 [Yersinia enterocolitica subsp. palearctica]
MIYKVKFRSDALKEWGKIDKVIQQQFAKKLKKCCENPHIPSAKLRGLSDCYKIKLRASGFRLVYQVIEDCLVIAVVAVGK
RERSDVYNLASERLR

Download         Length: 288 bp

>T108273 NZ_CP030980:549349-549636 [Yersinia enterocolitica subsp. palearctica]
ATGATTTATAAAGTAAAATTTAGAAGTGATGCCCTAAAGGAATGGGGAAAGATAGACAAAGTTATTCAACAGCAGTTTGC
TAAAAAACTCAAAAAATGTTGTGAAAATCCTCATATTCCATCAGCAAAATTACGCGGATTATCAGACTGCTATAAAATAA
AATTACGGGCATCTGGTTTTAGGTTAGTTTATCAAGTTATTGAAGATTGTTTAGTTATCGCCGTGGTTGCCGTCGGCAAA
CGCGAACGCAGTGATGTTTATAACCTCGCCAGTGAACGGTTACGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9270.65 Da        Isoelectric Point: 4.2264

>AT108273 WP_005156229.1 NZ_CP030980:549101-549352 [Yersinia enterocolitica subsp. palearctica]
MANIILSDTSASVSELKKNPMATVKAGAGYPVAILNRNQPAFYCIPAELYERMLDALDDQELIRLVTERESQPLIDVDLD
KYL

Download         Length: 252 bp

>AT108273 NZ_CP030980:549101-549352 [Yersinia enterocolitica subsp. palearctica]
ATGGCTAACATAATTTTAAGTGATACGAGCGCAAGTGTCAGCGAGTTAAAGAAAAACCCTATGGCCACAGTCAAAGCGGG
GGCGGGCTATCCAGTGGCTATTTTGAATAGAAACCAACCGGCATTTTATTGTATCCCCGCAGAATTATACGAGAGAATGC
TAGATGCCCTTGATGATCAAGAGCTTATCAGATTAGTTACCGAACGAGAGAGTCAGCCACTCATTGATGTAGATCTGGAT
AAGTATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FI46

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FI63

References