Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1377628..1378201 Replicon chromosome
Accession NZ_CP030944
Organism Arcobacter aquimarinus strain W63

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AAQM_RS06840 Protein ID WP_129094558.1
Coordinates 1377899..1378201 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AAQM_RS06835 Protein ID WP_129094557.1
Coordinates 1377628..1377909 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAQM_RS06805 1372741..1374630 - 1890 WP_129094551.1 TonB-dependent receptor -
AAQM_RS06810 1374709..1375638 - 930 WP_129094552.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
AAQM_RS06815 1375747..1376349 + 603 WP_129094553.1 RraA family protein -
AAQM_RS06820 1376370..1376741 - 372 WP_129094554.1 DUF393 domain-containing protein -
AAQM_RS06825 1376731..1377108 - 378 WP_129094555.1 S24 family peptidase -
AAQM_RS06830 1377101..1377397 - 297 WP_129094556.1 nucleotidyltransferase domain-containing protein -
AAQM_RS06835 1377628..1377909 - 282 WP_129094557.1 putative addiction module antidote protein Antitoxin
AAQM_RS06840 1377899..1378201 - 303 WP_129094558.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AAQM_RS06845 1378337..1379827 - 1491 WP_129094559.1 DUF2075 domain-containing protein -
AAQM_RS06850 1379851..1382220 - 2370 WP_129094560.1 SMC family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1330235..1386335 56100


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11732.46 Da        Isoelectric Point: 10.0753

>T108269 WP_129094558.1 NZ_CP030944:c1378201-1377899 [Arcobacter aquimarinus]
MYQIRQTNQFSSWLSKLKDVKGKVSIFRRIDRIRKGNFGDYKSVGGNIFELRFTIGPAYRVYYTKVEDEIILLLIAGDKS
TQSEDIKKAKELEKEYSNEK

Download         Length: 303 bp

>T108269 NZ_CP030944:c1378201-1377899 [Arcobacter aquimarinus]
ATGTATCAGATAAGACAAACTAATCAATTTTCATCTTGGTTATCAAAACTAAAAGATGTTAAAGGAAAAGTTTCAATTTT
TAGAAGAATTGACAGAATCCGAAAAGGCAATTTTGGAGACTATAAATCTGTTGGCGGAAATATATTTGAGCTTAGATTTA
CTATTGGACCAGCTTATAGAGTTTATTATACAAAAGTTGAAGATGAAATAATTCTTTTATTAATTGCTGGAGATAAATCT
ACACAAAGTGAAGATATAAAAAAAGCAAAAGAACTTGAAAAGGAGTATTCAAATGAAAAATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10348.87 Da        Isoelectric Point: 5.1037

>AT108269 WP_129094557.1 NZ_CP030944:c1377909-1377628 [Arcobacter aquimarinus]
MKNELTDFDISQYLDNKEVIAEYLTQVLEDGDIDELMMAIGNIAKAKGLTQISKDSGLGRESLYKTFNKGAKPRFDTVVR
VLNSLGIHLKATV

Download         Length: 282 bp

>AT108269 NZ_CP030944:c1377909-1377628 [Arcobacter aquimarinus]
ATGAAAAATGAATTAACAGATTTTGATATATCACAATATTTAGACAATAAAGAAGTAATTGCAGAATACTTAACTCAAGT
TTTAGAAGATGGTGATATTGATGAATTGATGATGGCTATTGGAAATATTGCAAAAGCAAAAGGACTAACTCAAATATCAA
AAGATTCAGGACTTGGAAGAGAGAGTTTATATAAAACTTTTAATAAAGGTGCAAAACCAAGATTTGATACAGTTGTAAGA
GTTTTAAATTCATTAGGCATTCATTTAAAAGCAACTGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References